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Senior Scientist (Small Molecule, Synthetics)

Amgen Inc

This senior scientist role focuses on small molecule drug product development within a cross-functional team. The successful candidate will design experiments, execute design-of-experiments studies, and provide technical chemistry expertise to support pivotal and commercial programs while collaborating across multiple departments including regulatory, quality, and clinical functions.

Responsibilities

  • Develop creative functional strategies and execute design-of-experiments for pivotal drug development programs
  • Apply organic chemistry expertise to innovate drug product development approaches within cross-functional teams
  • Design and execute experiments supporting drug product development objectives
  • Provide technical expertise on structure, reactivity, and physicochemical properties of drug substances and excipients
  • Summarize experimental results in technical documents, regulatory filings, and presentations

Requirements

  • PhD in organic chemistry, physical chemistry, chemical engineering, materials science, or pharmaceutical sciences
  • Deep understanding of organic molecules, their assemblies, and physicochemical properties
  • Expertise in solid-state chemistry and characterization techniques (XRPD, DSC, TGA, SEM)
  • Prior pharmaceutical industry experience with oral solid dosage forms
  • Proficiency in designing and conducting independent formulation research
  • Exceptional technical writing and cross-functional collaboration skills
Vacancy posted 5 days ago
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