Senior Research Associate
Meet Life Sciences
Research Associate / Senior Research Associate – Process Sciences (xRNA) We are seeking a highly motivated Research Associate / Senior Research Associate to support xRNA manufacturing and process development activities. This role will focus on in vitro transcription (IVT) production processes, downstream purification, process optimization, and analytical characterization to support xRNA drug substance manufacturing and scale-up activities. The successful candidate will have hands‑on experience with RNA process development, purification technologies, and analytical methods within a pharmaceutical or biotechnology environment. This is a laboratory and office‑based position reporting to Process Sciences Leadership. Key Responsibilities Perform and support in vitro transcription (IVT) reactions at small and intermediate scales. Support process development, troubleshooting, and optimization of IVT and downstream purification processes. Execute IVT reactions using stirred tank and wave bioreactor systems. Perform analytical testing to assess RNA purity and concentration using techniques such as Fragment Analyzer and NanoDrop. Support chromatography purification processes, including operation and optimization of purification workflows. Assist with process scale‑up, technology transfer, and manufacturing support activities. Maintain accurate documentation in accordance with GMP/GDP and internal/client requirements. Adhere to Good Laboratory Practices (GLP), biosafety standards, and safe laboratory procedures. Collaborate cross‑functionally with Process Sciences, Manufacturing, and Analytical teams to support development and production goals. Perform additional duties and project support activities as assigned. Qualifications & Requirements Education & Experience Bachelor’s degree in Pharmaceutical Sciences, Biotechnology, Engineering, or a related scientific discipline with 1–2 years of relevant industry experience; or a Master’s degree with relevant hands‑on experience. Experience supporting mRNA/xRNA drug substance process development and manufacturing activities. Hands‑on experience with IVT process development, optimization, and scale‑up activities. Experience operating AKTA chromatography systems and supporting purification process development. Knowledge and hands‑on experience with Tangential Flow Filtration (TFF) processes. Experience supporting technology transfer and/or scale‑up activities within process development environments. Technical Skills Experience with analytical characterization methods including: Fragment Analyzer / Capillary Electrophoresis (CE) Bioanalyzer / Gel Electrophoresis NanoDrop analysis Understanding of pharmaceutical and biotechnology manufacturing processes. Knowledge of biosafety and laboratory safety requirements (BSL standards). Strong documentation practices and attention to detail. #J-18808-Ljbffr Meet Life Sciences
$95k - $115k
Sana Biotechnology, Inc. is hiring a Senior Research Associate for its Cambridge location. You will lead media preparation for differentiating pluripotent stem cells into beta islet cells and execute various characterization assays. Strong hands-on expertise in histology...Senior$91.98k - $120k
Merida Biosciences in Cambridge, MA is seeking a Senior Research Associate to join their drug discovery team. The role demands a skilled lab-based biologist with an immunology background to contribute to preclinical drug discovery efforts. Responsibilities include executing...Senior- Monte Rosa Therapeutics, Inc is seeking a motivated High-Throughput Cellular Assay expert in Boston, Massachusetts. The role involves developing and optimizing cellular assays to evaluate target engagement and pathway modulation, using automation for cell-based screening...Senior
$74k - $100k
A pioneering biopharmaceutical firm is seeking a highly motivated Senior Research Associate/Associate Scientist in Biology to drive preclinical discovery efforts. The role requires expertise in preclinical oncology, including in vivo and in vitro studies. Candidates must...Senior- BioSpace is looking for a self-motivated individual to support in vivo experiments in the Infectious Disease Department. The role requires expertise working with murine models and experience in laboratory animal procedures. Responsibilities include conducting dosing and...Senior
- Initial Therapeutics, Inc. is seeking a talented scientist to join our Genome Sciences team. In this role, you will develop and execute cell-based and molecular assays, focusing on rigorous execution and collaborative efforts. The ideal candidate will have strong experience...SeniorFull time
- A pioneering neuroscience company in Cambridge, MA is looking for a Senior Research Associate to support neuronal production and characterization. This six-month contract position involves executing production and quality control of neuronal cultures, maintaining human...SeniorContract work
- ...of experiments on ELN. Qualifications MS or Ph.D. with inMolecular Biology, Biochemistry, Biology, orrelatedfield. The Senior Research Associate II level will have 4-6 years of relevent industrial experience and a Scientist wiill pocess 1-2 years industrial exerience...Senior
- About the Opportunity Senior Research Associate - laboratory-based role. The successful candidate will conduct cellular assays, develop novel cellular models, and elucidate complex mechanisms-of-action to support pharmacology strategy and drug discovery. Responsibilities...Senior
- Liberty Mutual Insurance in Boston, MA is looking for a Senior Associate Consultant to join their Corporate Strategy & Research team. The role involves providing strategic advice to senior executives on projects related to growth strategy and business transformation. Candidates...SeniorWork at office
- ...is well capitalized and has announced a $100M Series A nancing which supports the company into 2029. About the Role The Senior Research Associate, Cancer Biology role at Stipple Bio is a BS/MS level scientist position within the Research department, reporting to the Director...Senior
$91.98k - $120k
...passionate individuals to join our mission to transform treatment paradigms across the spectrum of antibody-driven diseases. Senior Research Associate (Merida Biosciences, Inc.; Cambridge, MA): The Senior Research Associate will be a skilled lab-based in vitro biologist...SeniorLocal area- Seeking a hands-on Senior Research Associate to advance, optimize, and execute molecular biology assays within a highly automated bioanalysis platform. This bench-focused role involves supporting method development, validation, and execution for preclinical and clinical...SeniorContract work
- ...and founders of successful high-profile biotechnology companies. We are seeking a highly motivated and technically skilled Research Associate to join our rapidly growing team. This role sits at the intersection of in vivo pharmacology and Immunology within the R&D department...Senior
- ...unlocking a new era of drug discovery in the CNS. Learn more at: Summary Of Position Quiver is seeking a highly motivated Senior Research Associate to join our Biology Group for a six month contract. This position will support and execute Quiver’s cutting‑edge neuronal...SeniorContract work
- ...hematology, and immunoassays from human and animal blood samples ( We are seeking a highly motivated and broadly skilled Senior Research Associate to support development of our growing diagnostic assay menu across veterinary medicine and the in vitro diagnostics (IVD)...Senior
$68k - $90k
...eager to help us advance these technologies from discovery research through clinical development. Join us in our quest to become... ...their families. About the Position Ratio is seeking a Research Associate / Senior Research Associate, Translational Pharmacology bench...SeniorWork experience placement$84k - $132k
By clicking the “Apply” button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda’s Privacy Notice and Terms of Use . I further attest that all information...SeniorMinimum wageFull timeTemporary workLocal area$81k - $107.3k
Ampersand Biomedicines is a Flagship Pioneering company on a mission to transform patients’ lives with programmed medicines that work precisely where needed, and nowhere else. We’re building a collaborative, mission-driven team that thrives in a fast-paced environment and...Senior$90k - $120k
Senior Research Associate, In Vivo Discovery Location: Boston, MA Reports to: Principal Scientist Job Type: Full-Time, Onsite About Us We are an innovative, stealth-mode biotech company developing in vivo gene editing therapeutics with a focus on targeted delivery of CRISPR...SeniorFull time$81k - $107.3k
Senior Research Associate, Translational Cambridge, MA Company Description Mirai Bio is a privately‑held, Flagship‑founded biotechnology company that is delivering genetic medicines from promise to performance. Mirai was built to solve one of the field’s central challenges...Senior$74k - $118.4k
...future sponsorship. Preferred Qualifications MS with 3+ years of relevant experience in biotech, pharma, or an academically rigorous research environment. Experience with LNP and lipoplex transfection, electroporation, or other nucleic acid delivery workflows. Familiarity...SeniorFull timeImmediate start- ...impact, bold and rigorous science, open collaboration, kindness & respect. Summary Triveni Bio is in search of a motivated Sr. Research Associate to play an important role in advancing the organization’s biologics research and development activities. This position will...SeniorFull time
- ...Overview Acrivon Therapeutics is seeking a highly motivated Research Associate to join the Drug Discovery team. This laboratory-based role will... ...optimization and workflow improvements under guidance from senior scientific staff. Collaborate cross-functionally with Biology...SeniorLocal area
- Company Summary Fathem is pioneering Visual IntelligenceTM to transform how scientists see, understand, and design biology. At the core of this vision is molecular vision at scale—the ability to directly observe molecular structure with the speed, throughput, and accessibility...SeniorLocal area
$95k - $115k
Senior Research Associate, Islet Cell Therapy Sana Biotechnology is growing, and we are hiring new team members who believe in the potential of engineered cells as medicines, who want to challenge status quo, and who lead with the desire to work on novel ideas. You will...Senior$76.1k - $114.1k
Job Description General Summary The Pharmacology Senior Research Associate conducts independent research to evaluate the effects of compounds on in vivo disease biology, with a strong emphasis on in vivo pharmacology and surgical execution in rodent models. This role requires...SeniorSummer workFlexible hours$80k - $102k
Your impact at LILA: We’re hiring a Senior Research Associate to support the development and execution of display workflows to determine the binding, stability, and function of antibodies and other biologics. The role will develop and execute assays to generate highly...SeniorFull timeWork at officeLocal areaFlexible hours$81k - $107.3k
Senior Research Associate, Fermentation Development Cambridge, MA USA COMPANY DESCRIPTION Flagship Pioneering is a platform innovation company that invents and builds companies that change the world. We bring together the greatest scientific minds with entrepreneurial...Senior$65k - $75k
...experience to benefit our customers and the world. Reporting to a Senior Scientist on the team, you will participate in the design and... ...the first 3 months, you’ll… Ramp up on the Callisto platform, associated genomics workflows, and internal tools. Learn and execute core...SeniorFull timeWork at officeRelocation
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