Sign up to access all features of our service.
  • Job search
  • Favorites
  • Create a CV
    New
  • Salaries
  • Subscriptions

Principal Scientific Data Scientist

Oakwell Hampton Group

We are a fast-growing startup backed by an Nvidia VP, working alongside top AI labs and global tech companies to build the foundational data layer that will power the next generation of AI-driven drug discovery.

We are conducting a confidential search for a senior scientific leader to oversee and execute our data strategy. We need a scientist who can lead—not just manage—and who brings a wealth of "big pharma" clinical experience to the table.

The Role

As our Principal Scientific Data Scientist, you will ensure our data is world-class, rigorous, and ready to train the AI models that will discover tomorrow's breakthrough therapeutics.

You will:

  • Lead the day-to-day operations and strategic direction of our biological data layer across multiple concurrent projects.
  • Leverage your deep expertise in bioinformatics and Real-World Data (RWD) to translate complex clinical needs into precise data specifications.
  • Draw heavily on your background in global pharma clinical programs to personally examine, validate, and enforce the scientific rigor of our data generation pipelines.
  • Manage a distributed network of PhD-level expert contractors to recruit, brief, review, and iterate on scientific data generation.

The Ideal Candidate

  • Education: Ph.D. in Bioinformatics, Computational Biology, Pharmacology, or a closely related life sciences field.
  • Domain Expertise: Extensive experience working within global pharmaceutical companies, with a strong focus on clinical programs and translational research.
  • Technical Skills: Deep bioinformatics expertise with a proven track record of handling Real-World Data (RWD), multi-omics datasets, and clinical trial data analysis pipelines.
  • Leadership: Demonstrated experience leading computational teams, managing complex data operations, and taking ownership of end-to-end data quality.
  • Mindset: Detail-obsessed, fast-moving, and possessing a "builder" mentality—you are a scientist first who understands the biology and can build the infrastructure to support it.

Why Join? This is an opportunity to join a founding team with real equity and make a massive impact at the most exciting intersection in biotech today: AI and drug discovery.

If you are a seasoned pharma scientist who is tired of big pharma bureaucracy and wants to build infrastructure that matters, we want to hear from you

Vacancy posted 4 days ago
Similar jobs that could be interesting for youBased on the Principal Scientific Data Scientist in Hayward, CA vacancy
  • $123k - $163k

     ...Principal Scientist 1 - Hayward, CA (Immunoanalytical services) About the Opportunity Meadowhawk...  ...• Be fully competent in all aspects of data processing and analysis, responsible...  ...to study status and any technical/scientific concerns. • Train and mentor more junior... 
    Principal
    Scientific
    Contract work
    Work at office

    Meadowhawk Biolabs, Inc

    Hayward, CA
    2 days ago
  •  ...established medical device company is seeking a Principal Scientist, AI/ML to help build and scale next-...  ...architecture, technical direction, and scientific execution across new product...  ...infrastructure, deployment strategy, and data management processes for AI-enabled systems... 
    Principal
    Scientific
    3 days per week

    SciPro

    Hayward, CA
    1 day ago
  •  ...Principal Account Executive – Life Sciences Team Location: Based in San Francisco or San Diego is preferred Position Profile...  ...development, GxP environments, R&D, quality, manufacturing, and scientific talent needs. Partner closely with recruiting and delivery... 
    Principal
    Scientific
    Contract work
    Work experience placement
    Remote work

    Impellam Group

    Hayward, CA
    15 hours ago
  •  ...Data Scientist MUST HAVE: STRONG DATA SCIENTIST WITH TABLEAU, SQL, NLP, TRANSFORMER TOOLS-BERT, PYTHON, COOMUNICATION SKILLS. LOCAL TO...  ...track record in solving business problems through fact-based and scientific analytics. ~ Comfortable in working with programming... 
    Scientific
    Local area

    Samprasoft

    Oakland, CA
    2 days ago
  • $201.7k - $267.3k

     ...Principal Data Scientist : Product to Market (P2M) Optimization Gap Inc. is seeking a Principal Data Scientist with deep expertise in operations research and machine learning to lead the design and deployment of advanced analytics solutions across the Product-to-Market... 
    Principal
    Minimum wage
    Temporary work

    Gap Inc.

    Pleasanton, CA
    3 days ago
  •  ...Principal Data Scientist Dublin, CA (Hybrid 1-2 days in a week) 12 Contract **LOCAL CANDIDATES ONLY** The role is Hybrid. 1-2 days a week in Dublin. There may be times when we need to travel to other locations such as Oakland, Concord, or field sites around... 
    Principal
    Contract work
    Local area
    2 days per week
    1 day per week

    Spectraforce Technologies

    Dublin, CA
    3 days ago
  •  ...team and position play a key role in equipping strategists with data-driven insights that help shape initiatives aimed at making...  ...strategic decision-making. The Product Insights and Reporting, Principal will report to the Senior Manager of Insights. Our leadership... 
    Principal
    Full time
    Part time
    Work at office
    Local area
    Work from home
    Home office
    2 days per week

    Blue Shield Of California

    Oakland, CA
    2 days ago
  • $147k

     ...Category: Business Operations / Strategy  Job Level: Manager/Principal Business Unit: Strategy & Growth Work Type: Hybrid Job...  ...recognized technical authority in applying advanced analytics—including data science, machine learning, operations research, engineering,... 
    Principal
    Work at office
    Remote work
    2 days per week
    3 days per week

    PG&E

    Oakland, CA
    4 days ago
  • $230k - $320k

     ...Principal - Construction Advisory ID 2023-1521 Location US-CA-Oakland...  ...Exponent is the only premium engineering and scientific consulting firm with the depth and...  ...improvements; risk and performance management; data analytics and information management;... 
    Principal
    Scientific
    Full time
    Work at office
    Flexible hours

    Exponent

    Oakland, CA
    3 days ago
  • $148.94k - $223.3k

     ...Pharmacist, Principal The Formulary Strategy and Pharmacy & Therapeutics team is responsible...  ...effectiveness, and budget impact data to support formulary decision making. You...  ...and provide P&T clinical support based on scientific evidence and standards of practice,... 
    Principal
    Scientific
    Full time
    Part time
    Work at office
    Local area
    Work from home
    Home office
    2 days per week

    Blue Shield Of California

    Oakland, CA
    1 day ago
  •  ...biomarker, for GLP/GCLP sample testing and data reporting. Present and interpret data...  .../or externally as needed. Serve as the Principal Investigator responsible for interaction...  ...Chemistry, Pharmacology, or other related scientific fields required, including a minimum of... 
    Principal
    Scientific

    Crystal Bio Solutions, a member of Crystal Pharmatech

    Pleasanton, CA
    3 days ago
  • $155k

     ...Job Category: Information Technology  Job Level: Manager/Principal Business Unit: Strategy & Growth Work Type: Hybrid Job...  ...Strategy and initiatives. Within this department the Reliability Data team is on point for a key role is developing and curating all... 
    Principal
    Work at office
    Remote work
    2 days per week
    3 days per week

    PG&E Corporation

    Oakland, CA
    4 days ago
  • $120k - $165k

     ...GLP/GCLP sample analysis and data reporting.   ~ Present and interpret...  ...as needed. ~ Serve as the Principal Investigator responsible for...  ...Expert, and mentor junior scientists.  ~ Assist in improving...  ...Pharmacology, or other related scientific fields required, including a... 
    Principal
    Scientific

    CRYSTAL PHARMATECH INC

    Pleasanton, CA
    28 days ago
  •  ...software solutions. The ideal candidate will collaborate with multidisciplinary teams to solve algorithmic challenges and contribute to high-performance software that drives scientific discovery. Competitive salary and equity participation are offered. #J-18808-Ljbffr N6.com
    Scientific

    N6.com

    Pleasanton, CA
    3 days ago
  • $127.9k - $204.6k

     ...Principal Data Engineer We are seeking a Principal Data & Advanced Analytics Engineer to help us unlock the next frontier of insight-driven decision making. The ideal candidate combines a passion for solving business problems with data, a deep understanding of Sales... 
    Principal
    Full time

    Cornerstone OnDemand

    Dublin, CA
    1 day ago
  •  ...Data Analyst/Data Scientist Join a high-performance agile Metrics, Analytics and Reporting Team (MART) within the Healthcare domain. Join...  ...5+ years of experience and proven track record in solving business problems through fact-based and scientific analytics.... 
    Scientific
    Work experience placement

    Samprasoft

    Oakland, CA
    2 days ago
  • $198.5k - $268.5k

     ...genuinely hard and genuinely consequential. We're hiring a Staff Data Scientist to own the sales analytics function within our Business...  ...and maintain price elasticity models that define the "scientific floor" for global discounting. You will translate these models... 
    Scientific
    Full time

    10X Genomics

    Pleasanton, CA
    3 days ago
  • $228k - $342k

     ...platform. About The Role As a Principal AI Researcher, you will be a...  ...Team. This is a role for a scientist‑leader who thrives on defining...  ...environment of global enterprise data. You will bridge the gap...  ...team, fostering a culture of scientific rigor, curiosity, and high‑velocity... 
    Principal
    Scientific
    Work at office
    Remote work
    Home office
    Flexible hours

    Workday

    Pleasanton, CA
    3 days ago
  •  ...leader in spectral technology, our advanced platforms enable deeper scientific discovery, empowering researchers in academic, clinical, and...  ...design controls. Proficiency with modeling, simulation, or data analysis tools such as CFD, MATLAB, or Python. PHYSICAL... 
    Principal
    Scientific
    Contract work
    Remote work

    Cytek Biosciences

    Fremont, CA
    22 hours ago
  • $115k

    Sr Specialist/Principal Specialist, QC Lab General, Fremont CA Description Employee assigned...  ...standard operating and QC procedures. Scientific and Quality lead for implementing novel...  ...analysis and interpretation of scientific data. Experience with computer-based systems... 
    Principal
    Scientific
    Work experience placement
    Local area

    Boehringer Ingelheim GmbH

    Fremont, CA
    4 days ago
  • $166k - $350k

     ...seeking a highly skilled and versatile Data Science / AI / ML Lead to lead the development...  ...data analysis using statistical and scientific methods; build proof-of-concept models...  ...communities of practice; mentor data scientists and engineers to propagate best practices... 
    Scientific
    Work at office
    Local area
    Remote work
    Flexible hours
    2 days per week
    3 days per week
    1 day per week

    Lam Research

    Fremont, CA
    2 days ago
  • $100k - $200k

     ...mothers, female executives, and scientists. At Abbott, we believe...  ...products that provide accurate data to drive better-informed...  ...The Opportunity The Principal RA Specialist will work on-site...  ...Qualifications Bachelor's Degree in Scientific discipline e.g. Chemistry,... 
    Principal
    Scientific
    Shift work

    Abbott

    Alameda, CA
    2 days ago
  • $100k - $200k

     ...mothers, female executives, and scientists. At Abbott, we believe...  ...products that provide accurate data to drive better-informed...  ...The Opportunity This Principal International Regulatory Operations...  ...Qualifications Bachelor's Degree in Scientific discipline e.g. Chemistry,... 
    Principal
    Scientific
    Worldwide
    Shift work

    Abbott

    Alameda, CA
    3 days ago
  • $168.2k - $227.6k

     ...About the Role Join our Data Platform team at 10x Genomics to architect and implement our strategic...  ...potential to change the world. We enable scientists to advance their research, allowing them to address scientific questions they did not even know they could ask... 
    Scientific
    Full time

    10X Genomics

    Pleasanton, CA
    2 days ago
  • $100k - $200k

     ...mothers, female executives, and scientists. The Opportunity This Principal Regulatory Affairs Specialist - APAC...  ...products that provide accurate data to drive better-informed decisions...  ...Bachelor's Degree in Scientific discipline e.g. Chemistry, Life Sciences... 
    Principal
    Scientific
    For contractors
    Shift work

    Abbott

    Alameda, CA
    1 day ago
  • $281.01k - $363.66k

     ...critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to...  ...Job Description for Executive Director of Clinical Data Engineering & Analytics (CDEA) Reporting to the Senior Vice... 
    Scientific
    For contractors
    Local area

    Gilead Sciences

    Foster, CA
    2 days ago
  •  ...Micro1 is seeking a Data Scientist to join their client’s team to turn data into actionable insights that drive business growth. You will harness your skills in statistics and programming to deliver impactful analyses in a dynamic environment. The role involves collecting... 
    Remote work

    Micro1

    San Leandro, CA
    8 days ago
  •  ..., and highly motivated ~ Strong work ethics and creative problem-solving abilities Preferred Skills Deep Learning Data visualization Scala NLP Django Roles and Responsibilities As an entry-level Python Developer, you need to perform the... 
    Part time
    H1b
    Remote work
    Relocation
    Flexible hours

    SynergisticIT

    Hayward, CA
    3 days ago
  •  ...toxicology-related activities Partner with internal and external scientific collaborators as needed QUALIFICATIONS Advanced degree...  ...Strong understanding of PK, PD, biomarker, and immunogenicity data Experience working in cross-functional clinical development... 
    Scientific
    Full time
    2 days per week
    3 days per week

    Meet Life Sciences

    Hayward, CA
    15 hours ago
  • $185k - $200k

     ...including, without limitation, individual education, experience, tenure, skills and abilities, internal equity and alignment with market data. In addition to a competitive market-based salary, Arcus offers the opportunity to participate in stock programs, a performance-... 
    Principal
    Work experience placement
    Work at office

    Arcus Biosciences

    Hayward, CA
    5 days ago

Do you want to receive more vacancies?

Subscribe and receive similar vacancies to Principal Scientific Data Scientist. Be the first to apply!