Scientist

Responsibilities Independently initiates and completes routine in vivo studies efficiently, with minimal supervision. Interprets experimental outcomes and recommends appropriate follow-up. Demonstrates technical proficiency supporting the development and validation of rodent models for cardiometabolic diseases. Applies basic scientific principles with minimal guidance; performs literature searches and extracts relevant information from published protocols. Proposes new ideas and technologies, builds support, and implements improvements based on scientific and technical expertise and an understanding of the drug discovery and development process. Independently operates and maintains laboratory equipment and troubleshoots issues effectively. Communicates work effectively, both orally and in writing; contributes to protocols, procedures, and technical reports; and provides input for scientific reports. Records, analyzes, and reports data with a high level of integrity and ethical conduct. Complies with applicable regulations and performs all work safely; maintains accurate records in accordance with Standard Operating Procedures and policies. Requires moderate physical activity to perform work in the vivarium and laboratory, including (but not limited to) standing for extended durations (>2 hours), working under a biosafety hood/cabinet for extended durations (>2 hours), bending, lifting (up to 20 lbs), squatting, pushing/pulling, and reaching. Also requires daily handling and restraint of small laboratory animals (rats, mice; >50 at a time), often within a specified timeframe. Requires use of personal protective equipment (PPE), including respiratory, eye, hand, and foot protection. Ability and willingness to work effectively in a highly collaborative environment and support weekend work as needed. Strong communication skills and ability to work collaboratively in a fast‑paced research environment. Skills Contributes to the design and execution of in vivo studies relevant to cardio‑renal metabolic diseases (kidney injury, cardiovascular and metabolic driven cardio‑renal dysfunction). Perform dosing procedures (oral gavage, IP/IV/SC injections), physiological monitoring, and sample collection (blood, urine, tissues). Conduct functional assessments, such as blood pressure measurements, echocardiography support, telemetry, metabolic cage studies, and renal function assays. Process and analyze biological samples, including histology, biomarker assays, qPCR, ELISA, and other molecular or biochemical readouts. Maintain high‑quality documentation, including study protocols, animal records, raw data, and reports compliant with internal and regulatory standards. Collaborate cross‑functionally with pharmacology, pathology, bioanalytics, and therapeutic area biology teams to interpret data and refine study designs. Ensure compliance with IACUC protocols, ethical animal care standards, and institutional guidelines. Contribute to scientific discussions, present data at team meetings, and support preparation of internal reports and external publications. Education Master's Degree with 2‑3 years experience or Bachelor's Degree with 3+ years experience in related scientific discipline; pharmaceutical, biotechnology or CRO experience is highly desirable; non‑PhD applicant required. Understanding of physiology, pharmacology, and disease mechanisms relevant to cardio‑renal biology. #J-18808-Ljbffr Ivory Systems