Executive Director, Medical Affairs Launch Strategy

Position Overview Bicara Therapeutics is seeking a strategic, scientifically rigorous and execution-driven leader to direct the pre-launch, launch, and lifecycle medical strategy for our oncology pipeline. Operating as a core member of the Oncology leadership team, you will bridge different cross functional teams to ensure the market is clinically prepared for successful therapeutic adoption. You will oversee medical education, data generation, and external collaborations to maximize patient impact. The ideal candidate combines strategic vision with hands-on launch execution within biotech or specialty pharma. This role is based in our Boston office and follows a hybrid schedule, with three in-office days each week and requires the ability to travel up to 40-50%. Responsibilities Launch Strategy, Readiness & Execution Co-development and execution of a comprehensive, long-term pre- and peri launch medical plan, ensuring alignment with commercial, clinical, and regulatory timelines. Translate medical strategy into actionable regional/local launch tactics, adapting to real-world clinical practice and stakeholder needs. Co-create and execute scientific narrative, disease-state education, and data dissemination strategy alongside Med comm/Sci Comm lead. Lead the operationalization of the Medical Launch Readiness Framework, including KPIs, milestones, and cross-functional accountability structures. Work with field medical affairs leader to define pre-launch KOL identification and mapping strategy, ensuring MSLs are engaged with key academic centers, community practices, and emerging thought leaders ahead of approval. Stakeholder Engagement and Advocacy Map, establish, and maintain trusted relationships with Tier-1 Oncology Key Opinion Leaders (KOLs), cooperative groups, and patient advocacy organizations. Develop with field lead and MSL team regional advisory board meetings to gather actionable insights on unmet needs and treatment paradigms. Represent the medical perspective in cross-functional forums and external medical congresses. Serve as a scientific resource to external stakeholders, building trust and credibility in the pre-launch and launch periods. Support the identification and development of emerging voices and scientific collaborators for advisory boards, publications, and congresses. Use field insights to inform medical strategies, evidence gaps, and unmet need identification. Cross-Functional Partnership Serve as MA representative on the Launch Core Team, working with field lead to integrate field medical strategy with commercial, market access, and medical education workstreams. Partner with HEOR and Market Access teams to support evidence needs and formulary discussions where medically appropriate. Collaborate with Clinical Operations on site identification, investigator engagement, and ongoing study support. Contribute to evidence generation planning, including IIS strategy, RWE initiatives, and registry opportunities. Partner with Commercial and Regulatory teams to ensure timely, accurate, and compliant review of educational and promotional materials. Maintain strict medical governance and compliance oversight for all external medical deliverables. Qualifications Advanced degree required: PharmD, MD, PhD, or equivalent in a relevant life sciences discipline. 12+ years of experience in Medical Affairs, with at least 5+ years supporting oncology product launches and lifecycle management. Deep therapeutic knowledge and proven ability to influence without authority, manage budgets and lead cross-functional matrix teams Exceptional verbal and written scientific communication skills with the ability to distill complex clinical data into digestible strategies. Experience at a biotech company navigating first or second product launch. Exposure to HEOR, RWE, or registry evidence generation in a field setting. Company Overview Bicara Therapeutics is a clinical-stage biotech company pioneering bifunctional antibodies for targeted tumor modulation. Founded in 2020, we've built a global team of over 100 employees headquartered in Boston, with a clear focus on advancing our lead asset, ficerafusp alfa, or FICERA - a potentially first-in-class bifunctional EGFR-directed antibody combined with a TGF-β ligand trap. Our innovative approach combines tumor-targeting with tumor modulation, where one arm localizes to the tumor while the other serves as a modulator, designed to deliver superior efficacy, improved safety, and enhanced durability directly at the tumor site. FICERA specifically addresses a key challenge in solid tumor treatment by enabling immune cell penetration into tumors, reducing fibrosis and immunosuppression while reversing TGF-β-driven resistance mechanisms - ultimately designed to drive the deep, durable responses that may translate into better outcomes and survival for patients. For more information, please visit Here at Bicara, we believe in building diverse teams and cultivating a culture where all voices are included. We encourage people from all backgrounds to apply. Bicara Therapeutics is an equal opportunity employer and will not discriminate against any employee or applicant on the basis of age, color, disability, gender, national origin, race, religion, sexual orientation, veteran status, or any classification protected by federal, state, or local law.