Senior Site Contracts Manager

Role Description

Senior Site Contracts Manager (Sponsor Dedicated /Remote - US Based)

Are you a contracts expert who thrives on navigating complexity, building strong site partnerships, and driving timelines forward? Syneos Health is seeking a Senior Site Contracts Manager to support a sponsor-dedicated program focused on high-impact Pharma & Vaccine studies. If you're energized by problem-solving, negotiation, and leading projects across multiple therapeutic areas-especially oncology-we'd love to meet you.

As a Senior Site Contracts Manager, you'll serve as a strategic expert responsible for developing, negotiating, and managing US site budgets and clinical trial agreements. You'll collaborate closely with internal teams, external stakeholders, and major academic institutions to craft robust contracts that support operational excellence while minimizing risk.

This role is perfect for a communicator, leader, and negotiator who's ready to hit the ground running and make an immediate impact.

Job Responsibilities

• Budgeting & Template Development:
  • Negotiate budgets from start to finish from a Sponsor perspective directly with clinical sites.
  • Fully understand budget and contract language for Pharma & Vaccine clinical trials.
  • Develop and refine templates to support consistency, compliance, and strategic study needs.
• Contract Negotiation & Risk Management:
  • Lead direct negotiations with large academic institutions and other critical stakeholders.
  • Draft and finalize clinical trial agreements that balance business objectives with legal and operational protections.
  • Conduct due diligence checks-such as FMV assessments and site justification reviews-when initial offers are declined.
  • Determine when requests require budget or language escalation and secure appropriate approvals.
• Project Leadership & Delivery:
  • Prioritize and lead multiple contracting projects across several therapeutic areas (oncology experience strongly preferred).
  • Proactively escalate risks, timeline impacts, or delays that could affect CTA execution.
• Tools, Systems & Communication:
  • Demonstrate expert proficiency in Excel and clinical trial management systems.
  • Communicate effectively in both written and verbal formats, incorporating feedback seamlessly.
  • Maintain accurate and timely updates in departmental trackers and databases.
• Compliance, Collaboration & Continuous Improvement:
  • Deepen and maintain knowledge of GCP, sponsor processes, SOPs, work instructions, and new technologies.
  • Build strong working relationships with internal and external partners.
  • Support and train additional team members as needed.
  • Contribute to process improvement initiatives that simplify workflows and eliminate inefficiencies.
  • Take on ad-hoc tasks and diverse projects with a solutions-oriented mindset.

Qualifications

• Oncology therapeutic area experience
• Prior experience with pharma, CRO, or investigative sites
• Strong project management skills and comfort leading cross-functional efforts
• Experience leveraging AI in the contracts and budgets space

Requirements

• 4+ years of experience working in a fast-paced and volume-driven work environment
• Direct experience negotiating with large academic institutions
• Ability to juggle priorities, lead projects, and deliver results under tight timelines
• Strong understanding of clinical study protocols, timelines, and site-related milestones (e.g., SIV)
• Bachelor's degree

Benefits

• Company car or car allowance
• Health benefits to include Medical, Dental, and Vision
• Company match 401k
• Eligibility to participate in Employee Stock Purchase Plan
• Eligibility to earn commissions/bonus based on company and individual performance
• Flexible paid time off (PTO) and sick time