Research Associate I, In Vivo

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Job Summary:

The Research Associate (RA) at Crown Bioscience North Carolina will support the execution of in vivo research studies, contributing to the advancement of oncology and pharmacology research. The RA will work closely with scientists and senior research staff to carry out experiments, maintain animal models, collect and analyze data, and assist in the development of novel research techniques. This position plays a critical role in ensuring the quality and integrity of preclinical studies.

Responsibilities:

• Assist study director/scientist and senior research associates (SRA) in the design and execution of research studies, including protocol and IACUC documentation.
• Develop, maintain, and manage xenograft models, including patient-derived xenografts (PDX), in rodent models.
• Perform in vivo procedures such as tumor cells inoculation/tumor fragment transplantation, tumor measurement, compound dosing (oral, IP, IV, etc.), and biological sample collection (blood, tissue, etc.), etc.
• Collect, organize, and interpret experimental data using standard data analysis software and methodologies.
• Contribute to the preparation of reports, summaries, and presentations of research findings.
• Collaborate with team members across departments and participate in internal/external project meetings to support study execution.
• Maintain precise and organized documentation of experimental procedures and results in lab records and study files.
• Ensure adherence to animal welfare regulations, research protocols, and laboratory best practices.
• Complete additional assignments or tasks as delegated by supervisors.

Minimum Requirements:

• Bachelor's degree in biology, pharmacology, physiology, animal science, or a related field.
• Strong analytical, observational, and problem-solving skills.
• Familiarity with in vivo research techniques and experience working with animal models.
• Proficiency in data collection and basic data analysis tools (e.g., Excel, GraphPad Prism).
• Excellent verbal and written communication skills.
• Ability to work independently and collaboratively in a fast-paced, team-oriented environment.

Preferred Requirements:

• Master’s degree in biology or pharmacology is preferred.
• Prior hands-on experience with rodent models, including surgical procedures, dosing, and sample collection.
• Experience working with patient-derived xenograft (PDX) models is strongly preferred.
• Familiarity with regulatory guidelines, including IACUC protocols and animal welfare standards.
• Experience contributing to peer-reviewed publications or scientific presentations is a plus.

Crown Bioscience is committed to a diverse and inclusive workplace. Crown Bioscience is an equal opportunity employer and does not discriminate based on race, national origin, gender, gender identity, sexual orientation, protected veteran status, disability, age, or other legally protected status. Crown Bioscience is a global contract research organization (CRO) providing discovery, preclinical, and translational platforms and services to advance oncology and immuno-oncology. Crown Bioscience is committed to a diverse and inclusive workplace. Crown Bioscience is an equal opportunity employer and does not discriminate on the basis of race, national origin, gender, gender identity, sexual orientation, protected veteran status, disability, age, or other legally protected status.

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