Senior LC-MS Bioanalysis Scientist: Target Dynamics & PK/PD
Amgen
Amgen is seeking a Senior Scientist in South San Francisco to lead the development of LC-MS bioanalytical assays. This role involves collaborating with cross-functional teams to support therapeutic candidates from preclinical development to regulatory submissions. The ideal candidate will possess a doctorate in relevant fields, strong quantitative skills, and hands-on LC-MS experience. Amgen provides a collaborative environment with competitive benefits aimed at professional and personal growth. #J-18808-Ljbffr Amgen
- ...transforming your career. Senior Scientist - LCMS Bioanalysis What you will do Let... ...apply innovative LC-MS-based bioanalytical... ...candidates, assess target engagement and... ...characterize target dynamics, and measure biomarkers... ...data in the context of PK/PD, translational...TargetSenior
- ...biotechnology firm in South San Francisco is seeking a highly motivated Senior Scientist in Bioanalytics. The candidate will lead bioanalytical... ...a Ph.D. with 7+ years experience or equivalent, strong LC-MS knowledge, and excellent communication skills. The anticipated...Senior
$125k - $180k
Clinical Development Scientist/Senior Clinical Development Scientist TenvieTherapeuticsis developing... ...fully CNS-penetrant NLRP3 inhibitor targeting cardiometabolicand... ...Clinical Pharmacology on endpoint hierarchy, PK/PD modeling plans, and interim analyses Drive...TargetSeniorInterim roleLocal areaRemote work- ...patients while transforming your career. Senior Scientist - siRNA Bioanalysis & Mechanistic Studies What you will... ...to serve patients. The dynamic professional we seek is a leader with... ...immunoassay and hybridization assays), LC/MS bioanalytical platforms, and nucleic...SeniorFlexible hours
$120.7k - $224.1k
...Translational Safety is seeking a highly motivated Senior Scientist / Principal Scientist to develop,... ...implement innovative platforms that enable target assessment, lead optimization, and safety evaluation across a dynamic portfolio, novel modalities, and emerging therapeutic...TargetSeniorLocal areaRelocation package$135k - $180k
...switching oligos, gapmers, steric-blocking oligos, and other RNA-targeting molecules against key targets. Select oligo chemistry (e.g.,... ...synthesize, purify, and quality control oligos using HPLC/UPLC, LC-MS, MALDI, UV quantification, PAGE, endotoxin/bioburden testing,...TargetSeniorH1bVisa sponsorship$145k - $220k
...across small‑molecule, peptide, and peptide‑adjacent programs, from target compound selection through synthesis, purification,... ...maintain key chemistry instrumentation, including HPLC/prep HPLC, LC‑MS, microwave‑assisted synthesis systems, and related analytical or...TargetSeniorH1bVisa sponsorship- Senior Scientist - Computational Systems & Predictive Biology This role focuses on developing scientific... ...of computational biology across target discovery and validation. You will... ...generation. What We Expect Of You The dynamic professional we seek is a Senior Scientist...TargetSeniorFlexible hours
$131.4k - $206.8k
...pathologists, gene expression scientists, image analysis specialists, assay... ...scientists to contribute to target validation, generation of... ...and development of response and PD biomarkers with line of sight... ...prediction. The Molecular Profiling Senior Scientist will work primarily...TargetSeniorFor contractorsRelocationVisa sponsorshipFlexible hoursShift work$196k - $242k
...tailored, potentially first‑in‑class targeted therapies aligned to the genetic... ...Summary We are seeking an accomplished Senior Principal Research Scientist in Computational Chemistry with significant... ...chemistry design. Use molecular dynamics, free energy methods, quantum...TargetSeniorTemporary workWork at officeLocal areaWork from home- Genentech in South San Francisco is seeking a Scientist III to join Translational Medicine. You... ...help identify and validate therapeutic targets and biomarkers using human clinical data... ...insights with mechanistic understanding across MS-related biology. The role demands...Senior
- Merck & Co. is seeking a Senior Scientist in South San Francisco to join their Respiratory Biology Discovery group. The ideal candidate will contribute to target identification and translational biology relevant to chronic lung diseases. Responsibilities include designing...TargetSenior
- Dormont Manufacturing Co is seeking a Senior Scientist to join the Respiratory Biology Discovery group in South San Francisco, CA. The role focuses on target identification, translational biology, and mechanism-of-action studies across COPD and other chronic lung diseases...TargetSenior
- F. Hoffmann-La Roche AG is looking for a highly motivated Senior ML Scientist to join the Foundation Models team in South San Francisco. This... ...focuses on pioneering AI research that impacts drug and target discovery. The ideal candidate will have a Ph.D. and a strong...TargetSenior
$229k - $269k
...clinical oncology company developing novel targeted therapies for patients with RAS-... .... The Opportunity We are seeking a Senior Machine Learning Scientist to help accelerate drug discovery... ...-related skills, experience, market dynamics, and relevant education or training....TargetSeniorFull timeLocal area$202.8k - $376.6k
...groups to translate machine‑learning innovation into insights for target discovery and disease understanding. Influence Organizational... ...scientific impact. Mentor Teams: Lead and mentor a team of scientists, fostering a culture of innovation, excellence, and collaboration...TargetSeniorLocal areaRelocation package- Onsite Job Title: Senior Associate Scientist Top Skills: 4-7 Experience in Cell/Tissue Culture, Protein Analysis BS Degree in Life Sciences The candidate... ...biology group to design and perform experiments, including target engagement methodologies and assay development to advance...TargetSeniorWork experience placement
$147.8k - $274.4k
...Opportunity We are seeking a highly motivated and collaborative Senior/Principal Machine Learning Scientist to join the Perturbation Biology group in the... ...large-scale high-content perturbation experiments for target and drug discovery. This role requires a deep...TargetSeniorLocal areaRelocation package- Job Description The Senior Scientist will join the Respiratory Biology Discovery group and contribute to target identification, translational biology, and mechanism‑of‑action studies supporting early discovery programs in chronic lung diseases, including COPD, bronchiectasis...TargetSenior
$200k - $250k
The opportunity As a full-time Senior Scientist on the Machine Learning team, you will work closely with engineers and experimental scientists... ...our R&D technology platform for RNA structure prediction, target identification, and early drug discovery. You will co‑lead the...TargetSeniorFull time- ...systems. The Molecular Profiling group focuses on understanding target tissue distributions in normal and diseased tissues,... ...therapeutics, and drug response prediction. The Molecular Profiling Senior Scientist will support the Discovery Oncology organization by providing...TargetSeniorRelocationVisa sponsorship
- ...bring them to more patients who need them. Your role As a Senior Machine Learning Scientist , you will play a leading role in designing the next... ...biological domains, i.e.: integrate models of chemical structure, target protein sequence and whole transcriptome scRNAseq. Stay...TargetSeniorWork at officeRelocation
- Senior Scientist Experimental Protein Design for Target Discovery What you will do In this vital role you will build and lead high-throughput platforms for binder generation, translating computational protein designs into experimentally validated minibinders and antibodies...TargetSeniorFlexible hours
$136k - $170k
...creation of medicines against historically hard‑to‑drug molecular targets. It is also developing foundation models for biology and... ...the Role Xaira is seeking a highly motivated and experienced Senior Scientist to join our Computational Biology team with a focus on supporting...TargetSeniorFlexible hours$147.8k - $274.4k
Opportunity We seek a highly motivated Senior ML Scientist to join the Foundation Models team (DELTA) within the AIBT (AI for Biology & Translation... ...AI research that delivers real‑world impact in drug and target discovery, with a focus on large‑scale foundation models in...TargetSeniorLocal areaRelocation package- ...highly talented and motivated Senior Scientist II to join our siRNA... ...concept activities, including target validation, assay development... ...Design in vivo studies (PK/PD, biodistribution, and efficacy... ...efforts. Qualifications PhD, MS, or BS in cell biology, molecular...TargetSeniorFull timeTemporary workLocal area
$156k - $166k
...year, we are at a pivotal inflection point. We are seeking a Senior Scientist to join our cardiac disease biology team. In this role, you... ...connect cellular phenotypes to disease mechanisms and therapeutic targets. Based in South San Francisco, this position reports directly...TargetSeniorWork at officeHome officeFlexible hours- Califesciences is seeking a Senior Scientist in South San Francisco to join the Pharmacokinetics & Drug Metabolism group. You will develop innovative LC-MS-based bioanalytical assays to support preclinical and clinical evaluations. The ideal candidate will hold a Doctorate...Senior
$100.4k - $186.4k
...disease. Within Multiple Sclerosis (MS), our team leverages human... ...heterogeneity, advance novel target understanding, and ensure that... ...talented and highly motivated Scientist 3 to join Genentech's... ...As an integral member of our dynamic team, you will: Contribute to...TargetLocal areaRelocation package$174k - $208k
SENIOR SCIENTIST, BIOANALYTICS Sutro Biopharma is seeking a highly motivated and experienced... ...This role requires deep expertise in LC-MS/MS-based bioanalysis and a proven track record of... ...considerations Qualifications Ph.D. in PK/ADME, analytical chemistry, or a related...Senior
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