Chief of Staff, Senior Director Global Regulatory Affairs

Chief of Staff, Senior Director Global Regulatory Affairs Introduction to role: The Chief of Staff (CoS) serves as a strategic partner to the VP, Head of Global Regulatory Affairs, enabling effective leadership, decision making, execution, and communication across the Global Regulatory Affairs organization. The role acts as an extension of the VP, ensuring alignment between strategy and execution, optimizing governance and leadership forums, and driving cross functional coordination at enterprise level. This role combines strategic advisory, operational leadership, and executive facilitation, with a strong focus on prioritization, organizational effectiveness, and delivery of strategic objectives. Accountabilities: Strategic Partnership and Advisory: Act as a trusted advisor to the VP on strategic, organizational, and operational matters; translate priorities into actionable plans; provide independent challenge to improve decisions and outcomes. Leadership Governance and Operating Rhythm: Own and optimize leadership governance and interfaces; shape agendas and decision frameworks; ensure decisions have clear owners, timelines, and follow-through that advances portfolio progress. Business Planning and Performance Management: Lead annual and multi-year planning; align objectives, KPIs, and resource plans with enterprise strategy; surface risks, trade-offs, and escalation points early to protect timelines and quality. Cross-Functional and Enterprise Coordination: Partner across R&D, Commercial, Safety, Medical, Legal, Finance, and Procurement to align competing priorities; coordinate across programs, therapy areas, and regions to resolve complex issues that impact filing readiness and approvals. Organizational Effectiveness and Change: Support organization design, capability building, and talent initiatives; lead change programs and improvements in ways of working that increase clarity, speed, and accountability across the regulatory organization. Executive Office and Communications: Run the Regulatory Affairs Executive Office; craft executive materials and narratives that drive decisions; represent the VP in internal forums to maintain momentum and continuity on critical deliverables. Essential Skills/Experience: Extensive experience in Regulatory Affairs, R&D, or closely related functions within a global organization Proven experience supporting senior executives or leadership teams Strong understanding of drug development, regulatory strategy, and governance models Experience operating in a matrixed, global environment Advanced degree in life sciences, regulatory affairs, or related discipline preferred Strategic thinking with the ability to translate strategy into execution Strong judgment and discretion in handling confidential and sensitive matters Exceptional stakeholder management and influencing skills across senior levels Leadership facilitation and decision framing Operational rigor with comfort managing ambiguity and complexity Change leadership and organizational effectiveness mindset Excellent written and verbal communication The annual base pay for this position ranges from $218,058.40 -$327,087 USD. Hourly and salaried non-exempt employees will also be paid overtime pay when working qualifying overtime hours. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles), to receive a retirement contribution (hourly roles), and commission payment eligibility (sales roles). Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors. Date Posted 10-Jul-2026 Closing Date 24-Jul-2026 Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form. AstraZeneca is a global, science-led, patient-focused biopharmaceutical company. We focus on discovering, developing and commercialising prescription medicines for some of the world’s most serious diseases. But we are more than one of the world’s leading pharmaceutical companies. At AstraZeneca, we’re dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science, challenge convention and unleash your entrepreneurial spirit. To embrace differences and take bold actions to drive the change needed to meet global healthcare and sustainability challenges. There is no better place to make a difference in medicine, patients, and society. An inclusive culture where you will connect different thinking to generate new and valuable opportunities. Where you will find a commitment to lifelong learning, growth and development for all. Our Inclusion & Diversity (I&D) mission is to create an inclusive and equitable environment where people belong, using the power of our diversity to push the boundaries of science to deliver life-changing medicines to patients. Inclusion and diversity are fundamental to the success of our company, because innovation requires breakthrough ideas that only come from a diverse workforce empowered to challenge conventional thinking. We’re curious about science and the advancement of knowledge. We find creative ways to approach new challenges. We’re driven to make the right choices and be accountable for our actions. As an organisation centred around what makes us human, we put a big focus on people. Across our business, we want colleagues to wake up excited about their day at the office, in the field, or in the lab. Along with our purpose to bring life-changing medicines to people across the globe, we have a promise to you: to help you realise the full breadth of your potential. Here, you’ll do work that has the potential to change your life and improve countless others. And, together with your team, you’ll shape a culture that unites and inspires us every day. This is your life at AstraZeneca.