Bioinformatics Scientist (52707)

Bioinformatics ScientistNational Institutes of Health (NIH) - Main Campus/Bethesda - Bethesda, MD 20892Salary Range $165,000.00 - $175,000.00 Salary/year Level Experienced Position Type Full Time Job Shift Day Education Level Masters Degree Travel Percentage None Category Public HealthDescriptionPosition Objective: The Bioinformatics Scientist will provide support services to the National Cancer Institute within the National Institutes of Health.Duties and Responsibilities:Use existing infrastructure and optimize Exome/Targeted/RNA Sequencing DataAnalysis pipelines for clinical sequencing projects.Develop pipelines to integrate complex genomic data including germ line, somatic DNA mutations, RNAseq and SNP assays.Work with staff on the production of a data compendium enumerating the frequency of variations from tumor/normal samples.Install and maintain local version of cBIO Portal.Upload Labs Data on cBIO Portal for easy visualization.Work with staff to utilize NIH Biowulf computer clusters to process data streamed off the next generation sequencers (NGS); process data in a batch mode. Perform biological sequence analysis/assembly and public genome databases.Collect and review data; analyze and interpret data and results; provide reports based on analysis of scientific data.Report research outcomes and make recommendations for future work.Work with staff on data visualization to support the preparation of presentations and manuscripts for submission to scientific journals.Bioinformatics Lab meetings, scheduling and notes writing.Co-write manuscripts.Develop annotation algorithms and databases with all publically available data including Annovar, 1000genomes, ExAC, MyCancerGenome, ClinSeq, ESP, ClinVar, HGMD and other databases as released.Develop new algorithms for analysis of next generation sequencing and other genomics data.Support implementation of publically available tools in local server environment.Write manuals to implement tools for other users.Teach staff to use NGS and other genomic analysis tools.Provide advice to staff about data analysis pipelines.QualificationsBasic Qualifications:Master's degree in Bioinformatics or related field of studySkilled in R, Next gen sequencing data analysis: Bulk RNA-SequencingSingle Cell RNA-Sequencing, and working with large data setsPreferred Qualifications:Ability to communicate effectively, orally and in writing, with non-technical and technical staffDetail-oriented and possess strong organizational skills with the ability to prioritize multiple tasks and projects GAP Solutions, Inc. (GAPSI)