Head Rare Diseases, US Medical Affairs
$303k - $428kBiogen Idec
About This RoleThe Head of Rare Diseases, US Medical is a critical leadership role within the US Medical organization, accountable for the strategic direction and execution of medical affairs activities across the Rare Diseases portfolio. This includes both marketed and pipeline assets in Spinal Muscular Atrophy (SMA), Amyotrophic Lateral Sclerosis (ALS), and Friedreich’s Ataxia (FA), among other emerging indications. The portfolio spans early access programs, lifecycle management studies, and multiple launched therapies, each supporting patients with high unmet needs and representing major growth opportunities for Biogen.As a key member of the North America Medical Leadership Team, this leader will report to the Head of Medical, North America. They will oversee a cross-functional medical team including Medical Directors, Field Director, and Medical Science Liaisons (MSLs), while collaborating closely with Global Medical teams, Regulatory, US Commercial, Market Access, and Value & Evidence Generation partners. This individual will represent the Rare Diseases medical perspective across senior leadership forums and ensure that the strategic priorities of the therapeutic area are aligned with broader corporate goals, all while advancing scientific knowledge, clinical impact, and patient outcomes.What You’ll DoLead the development and execution of the US Medical strategy across the Rare Diseases portfolio, encompassing multiple marketed products and late-stage development assets.Serve as the primary medical point of contact for Rare Diseases across US Commercial, Market Access, Global Medical, and Regulatory organizations.Oversee field medical strategy and operations for the Rare Diseases franchise, including Field Director and MSL teams.Provide leadership and strategic oversight for scientific content development, external stakeholder engagement, congress strategy, publications, and advisory boards.Ensure medical input is embedded in key cross-functional activities including lifecycle management, launch planning, and field enablement.Champion the integration of patient and HCP insights into strategic and tactical planning, ensuring a data-driven and customer-centric approach to decision-making.Lead with a performance-driven mindset, promoting accountability, innovation, and excellence across the Rare Diseases medical team.Mentor and develop medical affairs talent through intentional coaching, career path planning, and succession development.Represent Rare Diseases in cross-functional governance, promotional review committees, and compliance processes, ensuring rigorous execution and alignment with regulatory expectations.Manage and oversee the Rare Diseases medical budget, ensuring efficient resource utilization and investment in areas of highest impact.Who You AreYou are a purpose-driven and strategic medical leader with a passion for advancing care in rare and complex diseases. You have experience leading medical teams, building collaborative relationships across stakeholders, and delivering meaningful impact for patients and the business. You thrive in complexity, operate with integrity, and create environments where high performance and empathy can co-exist.QualificationsRequired SkillsMD, PhD, PharmD, or DNP in a clinical or scientific discipline.12+ years of Medical Affairs experience in roles with increasing responsibility and accountability for medical affairs planning & tactical execution. 5+ years of experience leading Medical Affairs teams across multiple products or within complex therapeutic areas.Demonstrated experience in developing and executing medical strategies for both marketed and pipeline assets.Deep understanding of medical engagement, regulatory environment, field medical operations, and scientific communication.Preferred SkillsExperience in Rare Diseases or Neurology strongly preferred.Proven success launching and supporting multiple products within a portfolio-based medical model.Comfort working in a fast-paced, matrixed environment with high strategic visibility.Track record of building and leading high-performing teams with a focus on talent development and inclusive leadership.Job Level: ManagementAdditional InformationThe base compensation range for this role is: $303,000.00-$428,000.00Base salary offered is determined through an analytical approach utilizing a combination of factors including, but not limited to, relevant skills & experience, job location, and internal equity.Regular employees are eligible to receive both short term and long-term incentives, including cash bonus and equity incentive opportunities, designed to reward recent achievements and recognize your future potential based on individual, business unit and company performance. In addition to compensation, Biogen offers a full and highly competitive range of benefits designed to support our employees’ and their families physical, financial, emotional, and social well-being; including, but not limited to:Medical, Dental, Vision, & Life insurancesFitness & Wellness programs including a fitness reimbursement Short- and Long-Term Disability insuranceA minimum of 15 days of paid vacation and an additional end-of-year shutdown time off (Dec 26-Dec 31)Up to 12 company paid holidays + 3 paid days off for Personal Significance 80 hours of sick time per calendar yearPaid Maternity and Parental Leave benefit 401(k) program participation with company matched contributionsEmployee stock purchase plan Tuition reimbursement of up to $10,000 per calendar year Employee Resource Groups participationWhy Biogen?We are a global team with a commitment to excellence, and a pioneering spirit. As a mid-sized biotechnology company, we provide the stability and resources of a well-established business while fostering an environment where individual contributions make a significant impact. Our team encompasses some of the most talented and passionate achievers who have unparalleled opportunities for learning, growth, and expanding their skills. Above all, we work together to deliver life-changing medicines, with every role playing a vital part in our mission. Caring Deeply. Achieving Excellence. Changing Lives.At Biogen, we are committed to building on our culture of inclusion and belonging that reflects the communities where we operate and the patients we serve. We know that diverse backgrounds, cultures, and perspectives make us a stronger and more innovative company, and we are focused on building teams where every employee feels empowered and inspired. Read on to learn more about Biogen.All qualified applicants will receive consideration for employment without regard to sex, gender identity or expression, sexual orientation, marital status, race, color, national origin, ancestry, ethnicity, religion, age, veteran status, disability, genetic information or any other basis protected by federal, state or local law. Biogen is an E-Verify Employer in the United States.SummaryLocation: Cambridge, MAType: Full time
$320k - $430k
Title: Vice President, Head of US Medical Affairs, Rare Disease Company: Ipsen Biopharmaceuticals Inc. About Ipsen: Ipsen is a mid-sized global biopharmaceutical company with a focus on transformative medicines in three therapeutic areas: Oncology, Rare Disease and Neuroscience...MedicalTemporary workFlexible hours- Sanofi is seeking the US Medical Head for Rare Blood Disorders in Cambridge, MA. You will lead the US RBD Medical Affairs team, shape medical plans, and collaborate with Global Medical, R&D, Safety, and Regulatory to support the portfolio spanning hemophilia and rare hematology...Medical
- Ipsen is seeking a Vice President, Head of US Medical Affairs, Rare Disease, to define and lead the US medical vision and strategy across its rare disease portfolio, including liver, bone and kidney initiatives. The role partners with Global Medical Affairs, R&D, Regulatory...Medical
- Sanofi in Cambridge, MA seeks a US Medical Head for Rare Blood Disorders to lead medical strategies across a broad portfolio including hemophilia... ...The role requires an advanced scientific degree and extensive Medical Affairs leadership experience, #J-18808-Ljbffr BioSpaceMedical
$232.5k - $335.83k
Job Title: Head of US Public Affairs & Patient Advocacy, ImmunologyLocation: Cambridge... ...close the gap between when disease begins and when patients... ...with immune challenges, rare diseases, cancers, and neurological... ..., Market Access, PSS, Medical Affairs, HEVA, and R&D to...MedicalFull timeShift work$162k - $223k
...Role The Associate Director, Medical Strategy & Operations (S&O... ...America (NA) Medical Affairs and a core member of Rare Disease LT. The role drives strategy... ...partners closely with the Head of Rare Disease and Medical... ..., and perspectives make us a stronger and more innovative...MedicalTemporary workLocal area$260k - $367k
...About This Role:As the Head of Commercial Field Excellence... ..., and supporting Medical field teams. You will... ...Neurology, Specialty, Rare Disease, and newly emerging areas... ...adjustments.Represent US BIO perspective in leadership... ...:Experience in Medical Affairs planning and tactical...MedicalFull timeTemporary workLocal area$389.59k
...severe and life-threatening diseases. Beyond our science, we live... ...that patients are counting on us to make the promise a... ...How You Will Achieve More:The Head of Medical Affairs, reporting to the EVP, Chief... ...gene therapy, gene editing, rare diseases, or expertise in cardiology...MedicalFull timeLocal areaShift work$231.99k - $347.98k
...Position : Senior Director, Head of Rare Neurology Thought Leader... ...Location : Boston, MA (US Headquarters for Alexion)... ...of people living with rare diseases. We lead with breakthrough science... ...among field commercial teams, medical affairs, marketing, and senior leadership...MedicalTemporary workLocal areaNight shift3 days per week$360k - $420k
Vice President, Head of Life Cycle Management Reporting directly to the Head of Medical Affairs, the VP, Head of Life Cycle Management (LCM... ...across our programs and disease areas of interest. The VP will... ...our careers website: About Us Alkermes applies its deep neuroscience...Medical$206.25k - $343.75k
Job title: US Senior Medical Director, Rare HematologyLocation: Cambridge, MA / Morristown... ...immune challenges, rare diseases, cancers, and neurological... ...member of the US Medical Affairs team within the Rare Blood... ...and reports to the Head of US Medical Affairs, Rare...MedicalFull time$252k - $378k
...DescriptionGeneral Summary:The Senior Director (non-MD) serves as a US Medical Affairs asset lead responsible for the strategic planning and... ...launch experience in nephrology, immunology, or rare disease strongly preferred.Experience managing and developing teams...MedicalFull timeSummer workRemote workFlexible hoursShift work2 days per week$162k - $223k
...critical operational aspects of US Medical. The S&O Lead’s role focuses... ...close collaboration with the Head of Medical Strategy,... ...experience required. e.g. Medical Affairs, Pharmaceutical Operations, etc... ...therapeutic areas of specialty and in rare diseases preferred.Experience in long-...MedicalTemporary workLocal areaWorldwide$151.08k - $226.62k
...do: The Associate Director, US HCP Peer-to-Peer (P2P) Marketing, gMG & NMOSD, Rare Neurology, is a member of the commercial... ...(TLL) team, Field Sales, and Medical Affairs to educate, engage, and enable... ...and HCP engagement ~ Rare disease / Specialty / high-value...MedicalTemporary workWork at officeNight shift$266.25k
Job Title: US Medical Head, Rare Blood Disorders Location: Cambridge, MA Join the team transforming... ...people with immune challenges, rare diseases, cancers, and neurological conditions.... ...Specialty Care North America Medical Affairs Leadership Team and leads the creation...MedicalLocal area$183k - $252k
...directly. About this role The Nephrology Associate Medical Director role is a part of US Medical Affairs, a strategic partner within Biogen, that helps... ...mission to find therapies for neurological and rare diseases is a unique focus within our industry and this shared...MedicalFull timeTemporary workLocal area- ...issues today and address the medical challenges of tomorrow. We strive... ...about AbbVie, please visit us at . Follow @abbvie on LinkedIn... ...for one or more molecules and diseases in the therapeutic area,... ...area(s); partners with Medical Affairs, Commercial and other functions...MedicalLocal area
$176.4k - $327.6k
Summary Job Title: Head of Adoption and Value Realization REQ-100... ...eligibility for annual equity awards. US-based eligible associates... ...Novartis: Helping people with disease and their families takes more... .... If, because of a medical condition or disability, you need...MedicalRelocation package- ...issues today and address the medical challenges of tomorrow. We strive... ...about AbbVie, please visit us at Follow @abbvie on LinkedIn... ...for one or more molecules and diseases in the therapeutic area, coordinating... ...(s); partners with Medical Affairs, Commercial and other...MedicalLocal area
$305k - $410k
...patients with immune-mediated diseases. Our product candidates... ...monoclonal antibody that presents us with an exciting opportunity... ...and strategic Vice President, Head of Biometrics to lead all biometrics... ...with Clinical Operations, Medical Affairs, Regulatory Affairs,...MedicalWork at officeLocal area- ...accessible, and high-quality medications, Azurity leverages its... ...Title: Vice President, Head of Medical – Anti-... ...including unmet need, disease burden, scientific... ...experience in Medical Affairs strategy roles within pharmaceutical... ...working across US and international...MedicalFull timeLive inWork at officeWork from home
$188.6k - $283k
Work Your Magic with us! Start your next chapter and join EMD Serono... ...Your Role:The Senior Counsel, Rare Tumors will provide... ...including both Commercial and Medical functions. Specifically, this... ...materials; advice regarding Medical Affairs and Medical Operations; manage...MedicalFlexible hours$228.2k - $358.6k
Medical Director, Clinical Science, GI2 TAU- Hematology/Rare Disease Are you looking for a patient-focused, innovation-driven company that will inspire you and empower you to shine? Join us as a Medical Director, Clinical Science, GI2 TAU- Hematology/Rare Disease in our...MedicalMinimum wageTemporary workWork at officeLocal areaRemote work- ...and the planet. This is what drives us as we research, develop, and market... ...status quo for the better. Chiesi Global Rare DiseasesChiesi Global Rare Diseases is a Chiesi Group’s business unit... ...research programs, while providing medical leadership as appropriate on cross-functional...MedicalHourly payWork at officeLocal areaRemote workRelocation packageFlexible hours
$267k - $377k
...Executive Director, Neuromuscular Disease (NMD) Marketing is responsible... ...close partnership across Medical, Market Access, Patient Services... ..., and work products. You have US commercial expertise and bring... ...industryExperience in rare disease preferredStrong analytical...MedicalFull timeTemporary workLocal area$190.5k - $265k
...with research ongoing in additional rare cholestatic liver diseases. WHAT - Main Responsibilities Brand Strategy... ...plan and operational budget for US market Own and drive the adult... ...projects simultaneously Strong scientific/medical aptitude and experience including knowledge...MedicalTemporary workFlexible hoursNight shift3 days per week- ...2026-09-10EMD Serono, Inc. seeks an Associate Director, US Medical Communications, Rare Tumors, to drive strategic medical communications maturation... ...corporate goals to support patient care in rare tumor diseases. Location is Seaport, MA; the role emphasizes cross-functional...Medical
$150.7k - $226k
...lives of patients with rare tumors. We developed... ...abilities can only help us find the answers that people... ...with finance, medical, legal, and regulatory.... ...and channel customers Head the strategy and execution... ...Oncology and/or rare disease experience Ability to...MedicalLocal area3 days per week$190k - $240k
DescriptionLocation: Remote, Eastern Territory US Reporting to: Senior Director, Medical Affairs - Americas Orchard Therapeutics, a... ...the lives of patients with rare disorders through innovative gene... ...(Sr MSL) is a therapeutic and disease area scientific expert for...MedicalFull timeLocal areaRemote work$143.25k - $210k
...Associate Director, Operations, Rare Disease Business Unit Company: Ipsen... ...we tackle areas of high unmet medical need through research and... ...alongside the company’s success. Join us on our journey towards... ...the National Sales Director and Head of Thought Leader Liaisons (TLLs...MedicalTemporary workHome officeFlexible hours
Do you want to receive more vacancies?
Subscribe and receive similar vacancies to Head Rare Diseases, US Medical Affairs. Be the first to apply!
- head Cambridge, MA
- head credit administration Cambridge, MA
- head golf professional Cambridge, MA
- head of architecture Cambridge, MA
- head of seo Cambridge, MA
- head of portfolio management Cambridge, MA
- med surg medical surgical rn registered nurse Cambridge, MA
- medical physics Cambridge, MA
- medical Cambridge, MA
- medical terminology Cambridge, MA



