Principal Drug Safety Scientist

Principal Drug Safety Scientist Date: Jul 6, 2026 Location: St. Louis, MO, United States, 63043 About Curium Curium is the world's largest nuclear medicine company with more than a century of industry experience. We develop, manufacture and distribute world‑class radiopharmaceutical products to help patients around the globe. Our proven heritage combined with a pioneering approach are the hallmarks to deliver innovation, excellence and unparalleled service. With manufacturing facilities across Europe and the United States, Curium delivers SPECT, PET and therapeutic radiopharmaceutical solutions for life‑threatening diseases to over 14 million patients annually. The name "Curium" honors the legacy of pioneering radioactive researchers Marie and Pierre Curie, after whom the radioactive element curium was named and emphasizes our focus on nuclear medicine. The tagline "Life Forward" represents our commitment to securing a brighter future for all those we serve: An enhanced quality of care for our patients. A trusted partner to our customers. A supportive employer to our valued team. Summary of Position Participate in adverse event (AE) case management, related adverse event management activities, processing cases under the single case ownership models to remain current with the activity and providing support in the management of the case and its prioritization. Support the entire lifecycle of products by applying sound medical judgment for analysis and interpretation of safety data for signal detection and safety risk management activities, including safety specification, PV planning, and risk minimization/mitigation in support. Work Schedule: M – F 8am – 5pm Essential Functions Process and evaluate AE reports according to standard operating procedures (SOPs): narrative, seriousness, causality, and expectedness assessment. Contribute to the preparation and quality control of safety aggregate reports, responses to authorities, company core data sheets, signal detection and assessment. Perform literature review for identification of case reports and other relevant safety information. Process, evaluate and support clinical trial activities as they relate to pharmacovigilance. Maintain an in-depth understanding of product knowledge and medical information publications, labeling, and relevant data for company products and maintain current awareness for the published literature. Act as the back‑up for the PV Manager of NA. Support PV physician medical evaluations. Contribute to quality improvement of relevant SOPs: review, prepare, and/or update local and global SOPs and working instructions as required. Interact with other departments (e.g. clinical development, quality, regulatory affairs, medical affairs) with regard to safety aspects. Maintain operational compliance with US and international regulatory agencies and guidelines (i.e. FDA, EU, HC, TGA, PIC/S, ISO, USP, NRC, cGMP, etc.). Requirements Bachelor or Master level degree in Pharmacy, Pharmacology, RPh, RN, or degree in Public Health or Epidemiology. 8 or more years of relevant Pharmacovigilance or medical experience. Pharmacovigilance experience preferred, as is experience in nuclear medicine or similar industry. Knowledge of domestic and international laws, regulations, and policies governing pharmacovigilance. Ability to understand and interpret federal regulations and company operating procedures to determine whether the event constitutes a potential safety issue. Ability to critically evaluate the published medical and scientific literature and write and update comprehensive, medically accurate, and scientifically fair‑balanced standard response documents for adverse events cases. Knowledge of Microsoft Office Suite (Outlook, Word, Excel, PowerPoint, and Teams). Excellent written and verbal communication skills. Must be able to prioritize and multi‑task with minimal supervision and participate in peer‑review process when processing medical inquiries and product complaints. Working Conditions Must be willing to travel as needed. Willingness to work in a team‑based environment. Close attention to detail required. May be required to sit or stand for long periods of time while performing duties. Must be able to work outside of regular work hours. Disclaimer The above statements are intended to describe the general nature and level of work being performed by employees assigned to this classification. They are not intended to be construed as an exhaustive list of all responsibilities, duties and skills required of employees assigned to this position. Equal Opportunity Employer Curium is an equal opportunity employer and believes everyone deserves respect, dignity and equality. All applicants will be considered for employment without attention to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran or disability status. We believe diversity includes disability, and we actively encourage applications from people with disabilities. If you require any accommodations during the recruitment process, please let us know—we are happy to support you. Job Segment Epidemiology, Public Health, Scientific, QC, Nuclear, Healthcare, Engineering, Quality, Energy #J-18808-Ljbffr Curium Pharma