Director, IT System Business Partner - Commercial and Medical

Director, IT System Business Partner - Commercial and Medical Hybrid Definium Therapeutics is a late-stage clinical biopharmaceutical company and our mission is to forge a new era of psychiatry by applying scientific rigor to psychedelics, with the goal of developing accessible treatments that unlock healing at scale. Our leadproductcandidate,lysergidetartrate(ourproprietary orally disintegrating tablet form oflysergide(LSD) D-tartrate),represents a highly differentiated, potential best-in-class opportunity for patients suffering from generalized anxiety, major depressive disorder, and posttraumatic stress disorder. Our early stage pipeline includes DT402, the R-enantiomer of MDMA and is under development to target the core symptoms of autism spectrum disorder (ASD), specifically addressing social communication challenges. Guided bythe recognitionthat patients deserve more than better, Definium is relentlessly advancing a new generation of therapeutics intended to addresstheunderlying causes of psychiatric and neurological disorders. By turning evidence into impact, Definium aims to change the trajectory of today’s mental health care crisis and enable a healthier future. Headquartered in New York, Definium Therapeutics trades on Nasdaq under the symbol DFTX. Together we are moving psychiatry forward—beyond better, into a boundless future. Join us! The Director, IT Systems Business Partner – Commercial and Medical serve as the primary strategic liaison between IT and Commercial (e.g. Sales, Marketing, and Market Access), Medical Affairs, and Health Economics and Outcomes Research (HEOR). This role ensures technology solutions are tightly aligned with commercial and medical strategy, regulatory obligations, and business objectives. The ideal candidate combines strong business acumen with IT administration and delivery experience, acting as a trusted advisor to business leaders while translating needs into scalable, secure, and compliant technology solutions. Responsibilities Act as the primary IT point of contact for Commercial and Medical Affairs leadership, developing strong, trust ‑ based partnerships Understand the Commercial and Medical Affairs strategy, business goals, and operational challenges, aligning business objectives to clear, prioritized IT initiatives and requirements Support systems and new product introduction by providing technical expertise, system administration, problem solving, and strategies for risk mitigation Support the overall governance and lifecycle management of commercial and Medical Affairs systems and platforms. (e.g., Veeva Vault CRM, Open Data, Link, Approved Email) Lead requirements gathering, documentation, and testing for commercial and Medical Affairs platforms. Ensure configuration, enhancement, and expansion of the systemsalignswith broader organizational data standards, information security practices, and regulatory needs Work closely with IT and Legal to ensure data protection controls such as segmentation and access boundaries are designed, implemented, and consistently enforced in alignment with regulatory requirement Ensure alignment between business demand and IT capacity and prioritization Provide oversight and system administration across SaaS platforms supporting Commercial operations and Medical Affairs. (e.g., CRM, field enablement, analytics, content management) Ensure solutions are scalable, user ‑ centric, and aligned with enterprise architecture standards Monitor delivery risks, dependencies, and change impacts; escalate as appropriate Serve as a clear communicator between technical and non ‑ technical stakeholders Drive change management, user adoption, and ongoing optimization of deployed solutions. Note that this is a hands-on role. A successful candidate will be expected to execute all above requirements with minimal assistance from staff. Qualifications: Bachelor’s degree in Information Systems, Business, or a related field (or equivalent experience) 7+ years of experience in IT, business systems, or technology business partnering roles supporting Commercial functions (Sales, Marketing, or adjacent teams) within a regulated life sciences environment 5+years ofexperience building and supporting CRM, Medical Affairs and Commercial enablement platforms. Veeva Commercial suite, Data Bricks, Snowflake, SQL experience strongly preferred Veeva certifications are strongly preferred Familiarity with regulatory frameworks (GxP, HIPAA, GDPR) and data integrity principles Exceptional communication and stakeholder management skills Proven ability to influence without authority and manage senior stakeholder relationships The starting base pay range for this position is $203,632.00-$233,500.00 Compensation will be determined based on several factors including, but not limited to, skill set, years of experience, and the employee’s geographic location. Employees in this role may be entitled to additional compensation, including bonus and equity. Benefits information is listed on our Jobs Page. The Company provides competitive benefits to employees including: 100% paid health benefits including Medical, Dental and Vision for you and your dependents 401(k) program with company match and vesting after the turn of the first month after your start date Flexible time off Generous parental leave and some fun fringe perks! #J-18808-Ljbffr Definium Therapeutics, Inc.