Senior Manager, Supply Chain

Revolution Medicines is a late-stage clinical oncology company developing novel targeted therapies for patients with RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) inhibitors designed to suppress diverse oncogenic variants of RAS proteins. The company’s RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development. As a new member of the Revolution Medicines team, you will join other outstanding professionals in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway. The Opportunity: Commercial Supplies Packaging Management. Serve as the primary technical point of contact for external contract packaging organizations and packaging component suppliers. Provide technical support for routine commercial packaging operations at external Contract Manufacturing Organizations (CMOs), including management of deviations, complaints, and investigations related to packaging, labeling, and logistics. Drive timely issue resolution to ensure product quality, regulatory compliance, and continuity of supply. Partner closely with Quality, Manufacturing, and external partners to ensure uninterrupted commercial supply. Support department leadership with resource planning and financial reporting activities. Initiate, review and approve internal and CMO specifications for primary, secondary, and tertiary packaging components used for commercial products. Author and maintain Bills of Materials (BOMs) and packaging process instructions for new and existing products. Collaborate with Technical Development to provide input on manufacturability, scalability, and packaging design for Revolution Medicine products. Lead or support technology transfer activities for packaging processes from development to commercial manufacturing. Participate in or lead packaging process validation activities for solid dose products across global manufacturing networks. Maintain awareness of and ensure compliance with cGMP, regulatory, and internal quality requirements applicable to global pharmaceutical packaging operations. Provide all packaging-related support to enable new product launches. Support regulatory submissions, inspections, and responses related to packaging and labeling and serialization activities, as needed. Ensure all supplies are controlled and distributed in accordance with GMP, GCP, and GDP. Develop, maintain and enforce department’s business processes and/or SOPs. Identify and implement process improvements to increase efficiency, reduce costs, and minimize waste. Required Experience, Skills, and Education: B.S. or M.S. in, Mechanical or Packaging Engineering, or related field with 8+ years of experience in pharmaceutical logistics and inventory management. Strong knowledge of cGMPs, pharmaceutical manufacturing principles, and global packaging standards. Technical proficiency, independent thinking, teamwork and collaboration, including driving continuous improvement. Demonstrated experience with primary, secondary and tertiary packaging for solid dose products Experience supporting new product introductions, technology transfers, and commercial launches in major global markets. Proven experience working with and managing external contract packaging organizations. Experience managing complex, cross functional projects across multiple regions and time zones. Knowledge of distribution and cold chain shipping requirements for pharmaceutical products; experience with shipping qualifications and transportation studies is a plus. Financial acumen related to budgeting, forecasting, and cost optimization. Working knowledge of statistical methods and software to support packaging process optimization and troubleshooting. Working knowledge of pharmaceutical commercial manufacturing, regulatory, and quality assurance. Solid project management, facilitation, and problem-solving skills. Solid organizational and time management skills. Strong communicator and connector between Commercial, Finance, Quality, Regulatory and Supply Chain teams. Effective, open, and transparent communication skills (verbal and written). Capable of working on multiple projects/tasks and able to meet timelines. Self-starter with a high level of comfort with ambiguity and complexity and the ability to multi-task while consistently delivering quality results. A team-oriented, progressive thinker who enjoys participating in an innovative and creative work environment. Preferred Skills, Experience and Education: Familiarity with pharmaceutical serialization requirements, including DSCSA and EU Falsified Medicines Directive (FMD). #LI-CT1 #LIHybrid The base pay salary range for this full-time position for candidates working onsite at our headquarters in Redwood City, CA is listed below. The range displayed on each job posting is intended to be the base pay salary range for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our base pay salary ranges are determined by role, level, and location. Individual base pay salary is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training. Please note that base pay salary range is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities. Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status. Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact View email address on click.appcast.io. Base Pay Salary Range

$164,000—$205,000 USD

We are aware of recent recruitment scams in which individuals or organizations falsely represent themselves as being affiliated with Revolution Medicines. These scams may appear as false job advertisements or unsolicited contacts through communication or chat platforms, email, phone, or text message. Please note that Revolution Medicines does not extend unsolicited employment offers and will never ask candidates to provide financial information, purchase equipment, or pay fees as part of the hiring process. All legitimate communication from Revolution Medicines will come from an official @revmed.com email address. If you believe you’ve been contacted by someone impersonating a Revolution Medicines recruiter, please report it to View email address on click.appcast.io so we can share these impersonations with our IT team for tracking and awareness.