Senior Scientist, Computational Biology & Data Infrastructure

OVERVIEW

At Kingdom, we’ve pioneered Superculture® ingredients: an entirely new class of clinically-validated postbiotics that target the root causes of unmet pet health needs. We’re actively selling Superculture® Pet Oral and Superculture® Pet Immune to pet food and supplement brands, and will be launching our first Superculture ingredient for humans later this year. We're looking for a high-performing Senior Scientist, Computational Biology & Data Infrastructure & Data Infrastructure, to join our small but mighty team. This is an AI-native science role: you'll own the computational backbone of Kingdom's research (the microbial genomics and AI-compatible data infrastructure that every wet-lab program depends on) and ship custom and integrated LLM tooling to automate and accelerate our work. We want a PhD-level computational biologist (or related area) who applies rigorous scientific judgment to genomic analysis, biobank strategy, and statistical methods, and is equally excited to build the systems that let everyone move faster. Fundamentally, this is a science role, with success measured by the integrity of our data, the insights our data infrastructure unlocks, and the AI tooling we deploy across our scientific platform. This is a full-time, in-person role at our headquarters in Brooklyn, NY.

RESPONSIBILITIES

In this role, you’ll report to the Senior Scientific Director, and will work closely with our science team & co-founders to: Own genomic analyses and biobank strategy: Run computational genomic safety analyses and author the supporting reports that underpin our regulatory and customer-facing safety documentation Maintain the whole-genome sequencing pipeline: assembly of incoming sequencing data, linkage of genomes to strain records, and curation of best-available assemblies for downstream use Own and operate the strain dereplication pipeline, advancing isolated colonies from primary 16S/ITS screening through unique-strain identification and entry into the biobank Design and curate screening plates for downstream functional assays, including layout, strain selection, and verification of taxonomy and safety annotations Build and own Kingdom’s AI-compatible scientific data infrastructure: Build AI-compatible data infrastructure for Kingdom that captures, stores, and analyzes data across a variety of modalities Develop and apply statistical and computational methods to power biological insights and support wet-lab workflows, including experimental design, metric development and validation, and method onboarding, powered with new AI/agentic tools Maintain the integrity of the strain database backend: tube tracking, naming conventions, and audits of our physical inventory and pipeline data to identify anomalies Model complex, interrelated scientific entities (samples, experiments, runs, results, physical inventory) into a coherent schema and ontology the team can work in Scope, build, and ship the data processing, analysis, and metrics that give new assays clear, validated benchmarks

COMPETENCIES & QUALIFICATIONS

PhD (or equivalent depth) in computational biology, bioinformatics, microbial genomics, or a related quantitative life-sciences field; ~1-3 years post-PhD Domain depth in microbial genomics: whole-genome sequencing, 16S/ITS amplicon analysis, dereplication, taxonomy, and genomic safety annotation Strong knowledge of statistics and quantitative methods Advanced coding literacy: expert-level Python or R, proficiency with SQL, fluency with containerization for reproducible pipelines, comfort building tools that interact with third-party APIs, and strong code-quality practices (version control, testing, code review) Experience designing and maintaining bio-data infrastructure: proficiency modeling complex interrelated entities and comfort establishing and communicating an ontology AI-native: daily Claude Code or equivalent use, prompt fluency, comfort rebuilding research cadence around agentic tools, with experience building tooling around your own research High agency: self-starter who identifies pain points, proposes a plan and solution, and drives their own learning Builder mentality: comfortable with building a first version of a tool fast, and iterating to improve Bias to actionable output: instinct to package findings into something concrete that unblocks decisions and moves the next step forward Clear and effective written and verbal communication

WHY JOIN KINGDOM

Meaningful work : contribute to a category-defining biotech company at the frontier of postbiotic science. Growth and learning: Kingdom’s scientific AI and data-infrastructure function is still being defined, so you’ll have real influence over what it becomes. Because the role supports every wet-lab program, you’ll gain broader exposure to microbial science and ingredient development. Ownership and autonomy: inherit a functioning biobank infrastructure and a working genomic-safety pipeline; AI data infrastructure: substantive work from day one, with substantial latitude to shape the platform. Early and sustained exposure to the Chief Science Officer. Team and culture: small but mighty team that's high-performing, kind, and AI-native.

OUR VALUES

Solve from first principles. We have a deep-seated curiosity about the most important problems facing the business. Our nature is to dig deeply into their details, question assumptions, understand the smallest details, and drive towards the best possible solution using these insights. This makes us very effective in crafting new solutions and operating in ambiguous circumstances. Collaborate with kindness. We are exceptionally low ego, and treat each other with respect, compassion, and humility. We hold one another to high standards, but do so while being deeply committed to each other's wellbeing. We invest in each other's growth, and are willing to engage in difficult conversations and deliver direct, constructive feedback when necessary. Be resourceful and resilient. We figure out how to make things work, and how to accomplish our goals regardless of what stands in the way. We're keen to confront challenges together through proactive planning and scrappy methods. When things go wrong, we learn quickly from our missteps, adapt our approach, and push forward.

COMPENSATION AND BENEFITS

To build a world-class team, Kingdom is transparent and generous with our compensation package. We anchor cash salary above market-rate compensation for your role, and go above and beyond with equity stock options, as we want everyone to be aligned with and benefit from our long-term success. For this position, we are most actively considering candidates at the Senior Scientist level (PhD with ~1-3 years of post-PhD experience; cash salary range: $132.5K-$160K). This does not include stock options, which we’ll discuss during the interview process. Kingdom additionally offers an excellent benefits package including: 100% fully-covered, best-in-class medical, vision, and dental insurance for yourself (and 95% for your spouse/family) Generous and flexible PTO, in addition to 13 company-wide holidays Full commuter coverage Fully stocked kitchen with fruits, snacks, and beverages + weekly team lunches 12-weeks fully-paid parental leave 401k program with minimal fees #J-18808-Ljbffr Kingdom