Vice President, Biologics Research

At Insmed, every moment and every patient counts — and so does every person who joins in. As a global biopharmaceutical company dedicated to transforming the lives of patients with serious and rare diseases, you’ll be part of a community that prioritizes the human experience, celebrates curiosity, and values every person’s contributions to meaningful progress. That commitment has earned us recognition as

Science

magazine’s No. 1 Top Employer for five consecutive years, certification as a Great Place to Work® in the U.S., and a place on

The Sunday Times

Best Places to Work list in the UK.

For patients, for each other, and for the future of science, we’re in. Are you? About the Role: We’re looking for a Vice President, Biologics Research to provide scientific, strategic, and organizational leadership for biologics discovery, engineering, and early-stage development at Insmed. You’ll report to the Head of Insmed’s east coast Research and work closely with senior leaders across R&D and the broader organization. You will help set the scientific vision for biologics research, ensure strong execution for discovery across multiple therapeutic modalities, and serve as a key partner to collaborating functions and stakeholders as we translate discovery science into clinical programs. You will combine deep expertise in protein engineering and immunology with hands-on experience advancing biotherapeutics from discovery into the clinic. The Biologics Research organization includes a growing group of >50 scientists and staff distributed across two research sites and comprising the following groups: •5+ large molecule discovery and engineering teams •AAV viral vector engineering team •AAV gene therapy discovery team •Immunology team •Computational biology and data science teams •Research bioprocess development team •In vivo model team

What You'll Do: Scientific Leadership and Strategy Define and drive the long-term scientific strategy for biologics research, ensuring alignment with corporate and portfolio objectives. Provide thought leadership for therapeutic targets, protein engineering, biologics modality selection, and biotherapeutic discovery, design, and development. Ensure scientific rigor, innovation, and data-driven decision-making across all biologics programs. Support expansion of laboratory automation and adoption of agentic AI-enabled workflows and decision-making. Drug Discovery and Preclinical Development Ensure seamless integration of computational biology, data science, and experimental efforts. Oversee and support teams through key milestones including establishing screening cascades, molecular design, candidate selection, preclinical development, and IND-enabling studies. Translation and Clinical Interface Support first-in-human readiness and provide input into clinical study design considerations. Partner with Technical Operations, Clinical, Toxicology, DMPK, Translational Bioanalytics, and Regulatory teams to support IND submissions and early clinical development. Provide scientific leadership in understanding human immune responses (CD8+, CD4+, and B cell responses) to protein antigens and the impact on safety, efficacy, and durability. People and Organizational Leadership Recruit, lead, and develop a high-performing and collaborative biologics research organization. Build strong scientific leadership at the director and senior director levels. Foster a culture of accountability, innovation, inclusion, and cross-functional collaboration. Cross-Functional and Executive Engagement Serve as a key member of the R&D leadership team and a scientific advisor to senior executives. Represent biologics research internally with cross-functional stakeholders and externally with collaborators, partners, and other 3rd parties. Who You Are: You have a PhD or equivalent degree along with 15 years of experience in biopharma or biotech R&D, with progressive leadership responsibility. You are: a strategic thinker with strong scientific judgment and the ability to balance innovation with execution.

an effective leader of multidisciplinary teams in a matrixed, fast-paced environment.

You have: expertise in protein engineering and knowledge of adaptive immunology.

general familiarity with modern protein design technologies (e.g., computational design, AI/ML-enabled approaches).

experience with biotherapeutic drug development, including:

in vivo pharmacology

PK/PD strategy

preclinical CMC

support for toxicology and safety assessment

support for first in human translation

excellent communication skills, with the ability to influence at the executive level and translate complex science into clear decisions.

a track record of successful cross-functional collaboration and delivery of high-impact programs.

Where You’ll Work This is an onsite position based out of our New Hampshire office, with flexibility for some remote work. Travel Requirements This role requires occasional travel (approximately 5%–15%) #LI-MC1 #LI-ONSITE Pay Range: $290,000.00-396,000.00 Annual

Life at Insmed

At Insmed, you’ll find a culture as human as our mission—intentionally designed for the people behind it. You deserve a workplace that reflects the same care you bring to your work each day, with support for how you work, how you grow, and how you show up for patients, your team, and yourself. Highlights of our U.S. offerings include: Comprehensive medical, dental, and vision coverage and mental health support, annual wellbeing reimbursement, and access to our Employee Assistance Program (EAP)

Generous paid time off policies, fertility and family-forming benefits, caregiver support, and flexible work schedules with purposeful in-person collaboration

401(k) plan with a competitive company match, annual equity awards, and participation in our Employee Stock Purchase Plan (ESPP), and company-paid life and disability insurance

Company Learning Institute providing access to LinkedIn Learning, skill building workshops, leadership programs, mentorship connections, and networking opportunities

Employee resource groups, service and recognition programs, and meaningful opportunities to connect, volunteer, and give back

Eligibility for specific programs may vary and is subject to the terms and conditions of each plan. Current Insmed Employees: Please apply via the Jobs Hub in Workday. Insmed Incorporated is an Equal Opportunity employer. We do not discriminate in hiring on the basis of physical or mental disability, protected veteran status, or any other characteristic protected by federal, state, or local law. All qualified applicants will receive consideration for employment without regard to sex, gender identity, sexual orientation, race, color, religion, national origin, disability, protected Veteran status, age, or any other characteristic protected by law. For more information, please refer to our

Equal Employment Opportunity and Non-Discrimination Statement

on our Careers site. It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability. Unsolicited resumes from agencies should not be forwarded to Insmed. Insmed will not be responsible for any fees arising from the use of resumes through this source. Insmed will only pay a fee to agencies if a formal agreement between Insmed and the agency has been established. The Human Resources department is responsible for all recruitment activities; please contact us directly to be considered for a formal agreement. Insmed is committed to providing access, equal opportunity, and reasonable accommodation for individuals with disabilities in employment, its services, programs, and activities. To request reasonable accommodation to participate in the job application or interview process, please contact us by email at

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and let us know the nature of your request and your contact information. Requests for accommodation will be considered on a case-by-case basis. Please note that only inquiries concerning a request for reasonable accommodation will be responded to from this email address. Applications are accepted for 5 calendar days from the date posted or until the position is filled.