Senior Director, Medical Information

Join Immatics and shape the future of cancer immunotherapy; one patient at a time!

Immatics is committed to making a meaningful impact on the lives of patients with cancer. We are the global leader in precision targeting of PRAME , a target expressed in more than 50 cancers. Our cutting-edge science and robust clinical pipeline form the broadest PRAME franchise with the most PRAME indications and modalities, spanning TCR T-cell therapies and TCR bispecifics.

Why Join Us?

• Innovative Environment: Help to pioneer advancements in cancer immunotherapy.
• Collaborative Culture: Be part of a diverse team dedicated to your professional growth.
• Global Impact: Contribute to therapies that make a lasting impact on patients globally.

Role Overview

The Senior Director, Medical Information (MI), will build and lead the Medical Information function in preparation for launch and future pipeline growth. This role will establish the strategy, infrastructure, content, governance, and external vendor partnerships needed for a scalable, compliant MI capability. A critical focus will be the end-to-end readiness of the MI call center vendor, from onboarding and integration through training, escalation pathways, quality oversight, and ongoing performance.

The Senior Director will also lead MI scientific content and evidence dossiers, oversee NCCN Compendia submissions, contribute to medical review and post-approval activities, and translate inquiry trends into actionable insights that inform Medical Affairs strategy.

Reports to : Executive Director, Medical Affairs

Location : Fully Remote, US

Salary Range : $270,000 - $295,000

Basic Qualifications:

• Bachelors degree in life sciences
• 15+ years of pharmaceutical or biotechnology experience, with substantial Medical Information and/or Medical Affairs experience and increasing leadership responsibility.

Preferred Qualifications:

• Advanced scientific or clinical degree required (PharmD, PhD, MD, or equivalent).
• Oncology experience strongly preferred; cell therapy experience is highly desirable.
• Experience supporting a U.S. product launch, particularly in an emerging or first-launch biotech environment.
• Experience building or scaling MI systems, processes, content capabilities, or launch-readiness infrastructure.
• Experience developing MI scientific content, including SRLs, custom medical responses, and FAQs.
• Demonstrated experience managing MI call center vendors, including onboarding, training, escalations, quality, and performance oversight.
• Strong knowledge of U.S. MI requirements, unsolicited inquiry response, pharmacovigilance and product complaint reporting, and relevant compliance standards.
• Strong scientific writing and judgment, with the ability to translate complex data into clear, balanced responses.
• Strong leadership, communication, project management, and cross-functional collaboration skills.
• Comfortable operating in a fast-paced biotech environment with multiple launch-critical priorities.
• Experience with payer evidence dossiers, NCCN Compendia or other oncology guideline/pathway submissions, and medical review committees.
• Experience with MI technology platforms, analytics, and emerging AI-enabled capabilities.

In this role you will:

MI Strategy & Infrastructure Development

• Build and evolve the U.S. MI strategy, operating model, and infrastructure for launch and pipeline growth.
• Establish governance, workflows, intake and triage processes, response standards, escalation pathways, and content lifecycle management.
• Develop and maintain MI SOPs, work instructions, training standards, and quality processes.
• Define the MI technology roadmap, including inquiry management, content repositories, literature surveillance, analytics, and appropriate use of AI-enabled tools.

Call Center Vendor Management & Launch Readiness

• Lead onboarding, integration, training, and ongoing management of the MI call center vendor.
• Own call center launch readiness, including systems, content, workflows, escalation pathways, safety and product complaint reporting, service levels, and business continuity.
• Establish vendor training and certification processes that evolve with new data, labeling and business needs.
• Oversee complex and escalated inquiries and connect the vendor with internal scientific experts when needed.
• Establish vendor KPIs, quality monitoring, governance, audit readiness, and corrective-action processes, including readiness assessments and launch simulations ahead of key milestones.

Scientific Content Leadership

• Lead MI content strategy and oversee development and maintenance of Standard Response Letters (SRLs), custom medical responses, FAQs, and other scientific response materials.
• Ensure MI content is accurate, current, evidence-based, balanced, and updated as new clinical data, safety information, labeling, and evidence emerges.
• Lead literature review, data synthesis, and development of responses to complex or novel unsolicited inquiries.
• Support scientific congresses with inquiry coverage, reference materials, escalation planning, and post-congress content updates.

Evidence Dossiers, Guidelines & Compendia

• Lead the development and lifecycle management of AMCP dossiers and other payer evidence resources in partnership with Medical Affairs, HEOR/RWE, Market Access, Regulatory, Legal, and other cross-functional stakeholders.
• Lead development and submission of evidence packages to the NCCN Drugs & Biologics Compendium, coordinating cross-functional input, review, and submission requirements.
• Support evidence submissions for other oncology guidelines and clinical pathways in collaboration with relevant internal experts.
• Ensure dossier and guideline/compendia materials are updated as evidence and external requirements change.

Cross-Functional Collaboration & Medical Review

• Serve as a scientific reviewer in PRC/MLR/MRC, with focus on medical accuracy, context, and balance.
• Partner cross-functionally to support post-approval long-term follow-up requirements for cellular therapies, including potential CIBMTR registry participation, postmarketing evidence activities, and related MI content and inquiry support.
• Partner across Medical Affairs, Clinical, Safety, Regulatory, Legal/Compliance, Market Access, HEOR/RWE, Quality, and Commercial to support launch and ongoing MI needs.
• Bring MI expertise to launch planning, including labeling readiness and interpretation, content priorities, inquiry forecasting, training, and day-one readiness.

Insights, Metrics & Reporting

• Establish MI metrics and reporting to monitor inquiry trends, service performance, and emerging scientific needs.
• Translate MI inquiries and trends into actionable insights that inform Medical Affairs strategy, content development, and cross-functional decision-making.
• Share key insights and performance updates with Medical Affairs leadership and cross-functional partners.

Leadership & Capability Building

• Build and develop the MI organization over time, including internal talent, contractors, vendor support, medical writing, and technology capabilities.
• Develop annual and longer-range MI plans, priorities, resource needs, and budgets.
• Foster a culture of scientific quality, accountability, collaboration, and practical problem-solving.

Travel Requirements:

• Approximately 10–20% travel, including scientific congresses, vendor meetings, and internal meetings; occasional international travel may be required.

Qualified candidates will participate in a structured interview process, which includes:

• An initial recruiter phone screen (conducted via video)
• Interviews with the hiring leader and other key stakeholders (via video)
• A final-stage interview

What do we offer?

At Immatics, we believe in investing in our team’s health, safety and well-being. Here’s what you can expect if you join Immatics

Comprehensive Benefits :

• Competitive rates for Health, Dental, and Vision Insurance
• 4 weeks of vacation, granted up front each year and prorated for first and last year of employment.
• 12 company paid holidays
• 7 days of sick time
• 100% employer-paid life insurance up to at 1x annual salary, up to one hundred thousand dollars
• 100% employer-paid short- and long-Term disability coverage
• 401(k) with immediate eligibility and company match. The company will match 100% of your contributions up to 3% of your base salary for the first two years of employment, 4% for years 2-3 of employment, and up to 5% of your salary from the fourth year onward of continued employment.
• Partially paid parental leave for eligible employees.
• Additional voluntary employee-paid benefits and services, including accident, hospital indemnity, and critical illness insuranc, as well as identity theft protection and pet insurance.

Equal Employment Opportunity

We are an equal opportunity employer and are committed to building a diverse and inclusive workplace. We consider all qualified applicants for employment without regard to race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity or expression, national origin, ancestry, age, marital status, disability, genetic information, veteran status, or any other status protected by applicable law.

Reasonable Accommodations

We are committed to providing reasonable accommodations to individuals with disabilities and to applicants with sincerely held religious beliefs, practices, or observances. If you require assistance or accommodation during the application or interview process, please contact us at View email address on aiapply.co .

Work Authorization

Applicants must be authorized to work in the United States without the need for current or future sponsorship.

Pre-Employment Requirements

Employment is contingent upon successful completion of a background check, reference checks and pre-employment drug screening, where permitted by applicable law. For certain roles, additional screenings such as a credit check or motor vehicle record review may be required, where job-related and consistent with business necessity.