RA-II/Sr. Research Associate, Protein Engineering

Job Description

Job Description

SystImmune is a leading and well-funded clinical-stage biopharmaceutical company located in Bothell, WA and Princeton, NJ. It specializes in developing innovative cancer treatments using its established drug development platforms, focusing on bi-specific, multi-specific antibodies, and antibody-drug conjugates (ADCs). SystImmune has multiple assets in various stages of clinical trials for solid tumor and hematologic indications. Alongside ongoing clinical trials. SystImmune has a robust preclinical pipeline of potential cancer therapeutics in the discover and IND-enabling stages, representing cutting-edge biologics development. We offer an opportunity for you to learn and grow while making significant contributions to the company's success. 

We are seeking a  Research Associate II or Senior Research Associate to join our  Protein Engineering team. This role is ideal for a highly motivated individual with strong molecular biology skills and a passion for scientific innovation. This position offers an exciting opportunity to work in a dynamic and innovative environment focused on the development of novel therapeutic antibodies.

This is a full-time onsite position in Bothell, WA.

Key Responsibilities:

• Perform routine and high-throughput molecular biology techniques, including library preparation, lentiviral vectors, PCR, restriction endonuclease digestion, Gibson Assembly, Golden Gate Assembly, bacterial transformations, and plasmid purification.
• Execute BLI, SPR, and other binding analytical assays, ensuring accurate and reproducible data to support characterization of protein candidates.
• Design mammalian expression plasmids and cloning strategies for proteins and multi-specific antibodies.
• Support high-throughput protein analytic workflows with automation to enable rapid screening and characterization of constructs.
• Maintain detailed records of experimental procedures and results in electronic lab notebooks.
• Collaborate with team members to support cloning and construct generation for protein expression.
• Assist in troubleshooting and optimizing molecular workflows to improve efficiency and throughput.
• Manage multiple tasks and projects simultaneously in a fast-paced environment.
• Maintain lab organization and inventory of reagents and supplies.

Required Skills & Qualifications:

• Bachelor’s or Master’s degree in Molecular Biology, Biochemistry, or a related field.
  • Research Associate II requires bachelor’s degree and 2+ years of industry experience.
  • Senior Research Associate requires bachelor’s degree with 5+ years or master’s degree with 3+ years of industry experience.
• 2+ years of hands-on lab experience in molecular biology techniques.
• Experience with antibody-related workflows is a plus.
• Liquid handler and automation experience are a plus.
• Experience with next-generation sequencing workflows is a plus.
• Strong organizational skills and attention to detail.
• Ability to work independently and as part of a collaborative team.
• Comfortable working in a dynamic environment with shifting priorities.

Compensation and Benefits: 

The expected base salary range for this position is $70,000 - $90,000 annually. Actual compensation will be based on a variety of factors, including but not limited to a candidate’s level qualifications, experience, and skills. 

While most offers typically fall within the low to mid-point of the range, we may extend an offer toward the higher end for exceptional candidates whose background and expertise exceeds the requirements of the role. 

SystImmune is a leading and well-funded biotech company with a bright future. We offer an opportunity for you to learn and grow while making significant contributions to the company’s success. SystImmune offers a comprehensive benefits package including: 100% paid employee premiums for medical/dental/vision, also STD, LTD, a 401(k) plan with a 50% company match of up to 3% and a vesting schedule of only 5 years, 15 PTO days per year, sick leave, plus 11 paid holidays and MORE. 

We offer an opportunity for you to learn and grow while making significant contributions to the company’s success. 

SystImmune is an Equal Opportunity Employer. We welcome diverse talent and encourage all qualified applicants to apply. 

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