Staff Software Engineer, Variant Classification

Labcorp is a global leader in laboratory services, providing the insights and answers that help healthcare providers, patients, researchers, pharmaceutical companies and health systems make confident decisions and improve outcomes. Through our unparalleled science, data, technology and laboratory network, we advance diagnostics, accelerate innovation and help address some of the world’s most important health challenges. As we shape the future of healthcare, we are leveraging advanced technologies, intelligent digital solutions and data-driven innovation across our operations to enhance how work gets done and deliver greater value to customers and patients. With our global scale and deep expertise, you’ll have the opportunity to do meaningful work, grow your career and make a real impact on people’s health around the world. Together, we’re improving health and improving lives.Labcorpis seeking aStaff Software Engineer, Variant Classificationto join ourLabcorpGeneticsteam.Work Schedule:This is a full‑time, exempt (salaried) position assigned to a First Shift schedule, with standard business hours of Monday through Friday, 8:00 a.m. to 5:00 p.m. in your local time zone.Business needs may occasionally require flexibility in work hours, including earlier, later, or additional hours, with reasonable notice provided when possible.Applicants who live within 35 miles of either the Burlington, NC or Durham, NC location will follow a hybrid schedule. This schedule includes a minimum of three in-office days per week at an assigned location, either Burlington or Durham, supporting both collaboration and flexibility.Job Responsibilities:Design and build tools that define, store, and provide meaningful variant, sample, and test level information to supportaccuratevariant interpretation and report generationDevelop andmaintainsystems that translate raw bioinformatic data into variant and sample level information, including registration, normalization, observation groups, and quality metricsScale andoptimizestorage of sample level information to support growing data needsSource,maintain, and provide annotations at the variant level necessary foraccuratevariant interpretationAutomate evidence placement and classification for variant interpretationSupport test content and assay development initiativesCollaborate with data scientists, variant scientists, and software developers to design and implement solutions that meet stakeholder requirementsMinimum Qualifications:Bachelor's degree with 10 or more years of recent professional software development experience10 or more years of experience with Python (intermediate level or higher)10 or more years of experience with relational databases and web development frameworks10 or more years of experience with front-end technologies (e.g., React, Angular, Vue.js, JavaScript/TypeScript, HTML/CSS)10 or more years of experience with RESTful APIs and microservices architecture10 or more years of experience with CI/CD pipelines and DevOps practices10 or more years of experience with cloud platforms (AWS, Azure, or GCP)Preferred Qualifications:Master's Degree or Ph.D. in Bioinformatics/Computational Biology or life sciences8 or more years of experience mentoring and developing senior and junior engineers across multiple teams8 or more years of experience defining technical vision and driving multi-year roadmaps3 or more years of experience with bioinformatic tools and annotation3 or more years of experience with variant databases and genomic data resources (e.g.,ClinVar,gnomAD, HGMD)3 or more years of experience in Spark, text mining, natural language processing, semantic enrichment, ontologies, data mining, or machine learning/AI3 or more years of experience with public-domain biomedical terminologies (e.g.,MeSH, NCIt, HGNC)3 or more years of experience translating complex scientific questions into information solutionsCurrent or prior Labcorp experienceAdditional Job Standards:Owns and delivers product or platform goals across multiple years and teams, setting a high standard for technical outcomes and deliveryDefines the vision, scope, and technical approach for large, business-impacting projects with organization-wide implicationsIdentifies, prioritizes, and drives solutions to ambiguous, open-ended problems across multiple teamsInfluences the roadmaps of partner teams to align with and achieve broader business goalsServes as a role model and technical authority for engineers across multiple teamsEffective verbal and written communicator with both scientific and non-scientific audiencesEffective with GitHub Copilot, Claude Code or similar LLM tools to accelerate coding, testing and documentationAboutLabcorpGeneticsLabcorp Genetics (formerlyInvitae) is dedicated to bringing comprehensive genetic information into mainstream medicine to improve healthcare for billions of people. The Variant Classification team builds andmaintainsthe tools that define, store, and provide meaningful and detailed variant, sample, and test level information to supportaccuratevariant interpretation and report generation. Our services supportinterpretation reportingof genetic variants and assay development across a suite of critical platforms including SDS, VDB, Argus,iVEP, Evidence Service,MoonPy, Cerebro, Universal Transcript Archive,SeqRepo, and Assay CMS.AtLabcorpwe have a passion for helping people live happy and healthy lives. Every day we provide vital information that helps our clients and patients understand their health. If you are passionate about helping people and have a drive for service, thenLabcorpcould be a great next career step!Application Window:10/31/2026Pay Range:$100K - $198K/yrAll job offers will bebased on a candidate’s skills and prior relevant experience, applicabledegrees/certifications,as well as internal equity and market data.LBP Only:The position is also eligible for an annual bonus under the Labcorp Bonus Plan.Bonuses are payable based on corporate and/or business segment performance and are subject to individual performance modifiers.Benefits:Employees regularly scheduled to work 20 or more hours per week are eligible for comprehensive benefits including: Medical, Dental, Vision, Life, STD/LTD, 401(k), Paid Time Off (PTO) or Flexible Time Off (FTO), Tuition Reimbursement and Employee Stock Purchase Plan.Employees regularly scheduled to work less than 20 hours, Casual, Intern, and Temporary employees are only eligible to participate in the 401(k) Plan.Employees who are regularly scheduled toworka 7 on/7 off schedule are eligible to receive all the foregoing benefits except PTO or FTO. For more detailed information, please click here. Labcorp is proud to be an Equal Opportunity Employer:Labcorp strives for inclusion and belonging in the workforce and does not tolerate harassment or discrimination of any kind. We make employment decisions based on the needs of our business and the qualifications and merit of the individual. Qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex (including pregnancy, childbirth, or related medical conditions), family or parental status, marital, civil union or domestic partnership status, sexual orientation, gender identity, gender expression, personal appearance, age, veteran status, disability, genetic information, or any other legally protected characteristic. Additionally, all qualified applicants with arrest or conviction records will be considered for employment in accordance with applicable law.We encourage all to applyIf you are an individual with a disability who needs assistance using our online tools to search and apply for jobs, or needs an accommodation, please visit ouraccessibility siteor contact us atLabcorp Accessibility. Formore information about how we collect and store your personal data, please see ourPrivacy Statement.Job SummaryJob number: 2612888Profession: Information Technology