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Director, Total Productive Maintenance (TPM) - (USA REMOTE)

$200k - $225k

Danaher Corporation

Durham, NC
  • Remote job

Are you ready to accelerate your potential and make a real difference within life sciences, diagnostics and biotechnology? At Beckman Coulter Diagnostics, one of Danaher’s ( 15+ operating companies, our work saves lives—and we’re all united by a shared commitment to innovate for tangible impact. You’ll thrive in a culture of belonging where you and your unique viewpoint matter. And by harnessing Danaher’s system of continuous improvement, you help turn ideas into impact – innovating at the speed of life. As a global leader in clinical diagnostics, Beckman Coulter Diagnostics has challenged convention to elevate the diagnostic laboratory’s role in improving patient health for more than 90 years. Our diagnostic solutions are used in routine and complex clinical testing, and are used in hospitals, reference and research laboratories, and physician offices around the world. Every hour around the world, more than one million tests are run on Beckman Coulter Diagnostics systems, impacting 1.2 billion patients and more than three million clinicians per year. From uncovering the next clinical breakthrough, to rapid and reliable sample analysis, to more rigorous decision making—we are enabling clinicians to deliver the best possible care to their patients with improved efficiency, clinical confidence, adaptive collaboration, and accelerated intelligence. Learn about the Danaher Business System which makes everything possible. The Director of Total Productive Maintenance (TPM) leads the strategy, governance, and execution of preventive and predictive maintenance programs across a GMP‑regulated life sciences manufacturing network. This role ensures that equipment, utilities, and facilities operate at peak reliability to support uninterrupted production of life‑saving therapies. The Director drives a culture of operational excellence, compliance, and continuous improvement while partnering closely with Manufacturing, Quality, Engineering, EHS, and Supply Chain. This position reports to the VP, Engineering and is part of the Global Engineering Team. In this role, you will have the opportunity to: Enterprise TPM Strategy & Governance – Provide enterprise leadership for the TPM strategy, ensuring alignment with manufacturing performance, quality systems, regulatory expectations, and long‑term business objectives, including asset lifecycle and modernization planning. Maintenance Operating Model & Programs – Establish and govern standardized preventive, predictive, and condition‑based maintenance frameworks for GMP equipment, clean utilities, and critical infrastructure across sites. Reliability & Operational Performance – Lead enterprise reliability and operational excellence initiatives, leveraging RCM, RCA, and FMEA to improve asset availability, reduce unplanned downtime, and drive sustained performance improvement. TPM Pillars & Culture of Continuous Improvement – Sponsor and embed TPM pillars—including Autonomous Maintenance, Focused Improvement, and Early Equipment Management—to drive accountability, operator ownership, and continuous improvement culture. Regulatory Compliance & Risk Oversight – Maintain executive accountability for maintenance compliance with cGMP, GxP, EHS, and global regulatory standards, overseeing audit readiness, inspection support, and critical asset risk management. Digital Enablement & Systems Optimization – Direct the enterprise CMMS/EAM and digital maintenance strategy, ensuring data integrity, asset visibility, and adoption of advanced technologies to improve reliability, cost, and decision‑making. People, Stakeholder & External Partnership Leadership – Lead and develop maintenance leadership teams while partnering with Manufacturing, Quality, Engineering, and key vendors/OEMs to align priorities, optimize shutdown execution, and support enterprise objectives. Travel, Motor Vehicle Record & Physical/Environment Requirements: if applicable for role Bachelor’s degree in Engineering (Mechanical, Electrical, Chemical, Industrial) or related field. 10+ years of maintenance, engineering, or operations experience in a GMP life sciences environment (biotech, pharma, medical devices). 5+ years of leadership experience managing multi‑site or large‑scale maintenance programs. Strong knowledge of TPM methodologies, reliability engineering, and CMMS/EAM systems. Demonstrated success improving equipment reliability and reducing downtime in regulated manufacturing. Ability to travel ~30‑40% if located in the Chaska, MN area, and ~50‑70% if remote. It would be a plus if you also possess previous experience in: Master’s degree in Engineering, Operations, or Business. Certifications such as CMRP, CRE, PMP, or Lean Six Sigma. Experience with biologics, sterile manufacturing, or high‑complexity production environments. Familiarity with digital maintenance technologies and Industry 4.0 applications. Beckman Coulter Diagnostics, a Danaher operating company, offers a broad array of comprehensive, competitive benefit programs that add value to our lives. Whether it’s a health care program or paid time off, our programs contribute to life beyond the job. Check out our benefits at Danaher Benefits Info ( At Beckman Coulter Diagnostics we believe in designing a better, more sustainable workforce. We recognize the benefits of flexible, remote working arrangements for eligible roles and are committed to providing enriching careers, no matter the work arrangement. This position is eligible for a remote work arrangement in which you can work remotely from your home. Additional information about this remote work arrangement will be provided by your interview team. Explore the flexibility and challenge that working for Beckman Coulter Diagnostics can provide. The annual salary range or the hourly range for this role is $ 200 K - $225 K. This is the range that we in good faith believe is the range of possible compensation for this role at the time of this posting. This range may be modified in the future. This job is also eligible for bonus/incentive pay. We offer a comprehensive package of benefits including paid time off, medical/dental/vision insurance and 401(k) to eligible employees. Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determined. The amount and availability of any bonus, commission, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company’s sole discretion unless and until paid and may be modified at the Company’s sole discretion, consistent with the law.

#LI-AY1

Join our winning team today. Together, we’ll accelerate the real‑life impact of tomorrow’s science and technology. We partner with customers across the globe to help them solve their most complex challenges, architecting solutions that bring the power of science to life. For more information, visit Danaher Corporation and all Danaher Companies are committed to equal opportunity regardless of race, color, national origin, religion, sex, age, marital status, disability, veteran status, sexual orientation, gender identity, or other characteristics protected by law. The U.S. EEO posters are available here ( We comply with federal and state disability laws and make reasonable accommodations for applicants and employees with disabilities. If reasonable accommodation is needed to participate in the job application or interview process, to perform essential job functions, and/or to receive other benefits and privileges of employment, please contact:View phone number on click.appcast.io or View email address on click.appcast.io. #J-18808-Ljbffr Danaher Corporation

Vacancy posted 1 day ago
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