Instructor, Research Faculty Appointment, Genomic Medicine

MISSION STATEMENT

The mission of UT MD Anderson is to eliminate cancer in Texas, the nation, and the world through outstanding programs that integrate patient care, research and prevention, and through education for undergraduate and graduate students, trainees, professionals, employees and the public.

SUMMARY

The primary purpose of the Instructor, Research Faculty Appointment (RFA), position in the Department of Genomic Medicine is to conduct mechanistic and translational research on epigenetic regulation of cancer and immune-cell function, with emphasis on developing approaches to improve cellular immunotherapy. The Instructor will lead defined research projects, contribute to publications and grant applications, collaborate with scientific and clinical investigators, and mentor trainees and research personnel under the guidance of the supervising Professor. Effort will be allocated to research (90%), administrative activities (5%), and education (5%). No direct patient care responsibilities are assigned.

ESSENTIAL JOB FUNCTIONS

Research

• Promise of ability to participate in collaborative research and in team science.
• Lead defined projects investigating how enhancer activity and chromatin regulation influence tumor progression, therapeutic response, and immune-cell dysfunction.
• Develop and evaluate epigenetic editing approaches to improve T-cell function and persistence for adoptive cellular immunotherapy, including tumor-infiltrating lymphocyte therapies.
• Design, conduct, and interpret CRISPR-based functional screens, chromatin profiling, single-cell multiomic analyses, and cellular and preclinical validation studies.
• Collaborate with clinical, computational, and laboratory investigators to identify therapeutic targets and advance patient-relevant research across cancer types.
• Prepare manuscripts and scientific presentations; contribute to research protocols, intellectual property disclosures, and translational development as appropriate.
• Generate preliminary data and contribute to collaborative grant applications and progress reports; develop proposals as PI or Co-PI where institutional and sponsor requirements permit.

Administrative

• Shows promise for institutional service.
• Complies with all policies and procedures.
• Contribute to research planning, project coordination, and responsible stewardship of data, reagents, equipment, and other research resources.
• Maintain accurate research records and reproducible workflows; support laboratory safety, research integrity, and compliance with applicable institutional policies and approved protocols.

Education

• Shows promise as an educator and mentor.
• Mentor trainees and research personnel in experimental design, epigenomic methods, functional genomics, data interpretation, and responsible conduct of research.
• Participate in laboratory and departmental educational activities and provide feedback on scientific presentations, manuscripts, and research projects.

REQUIREMENTS:

Education:

• Doctorate-level degree in a field appropriate to faculty role and/or department mission.

Experience:

• At least 2 years' postdoctoral experience preferred or equivalent time as a basic scientist.
  The University of Texas MD Anderson Cancer Center offers excellent benefits , including medical, dental, paid time off , retirement , tuition benefits, educational opportunities, and individual and team recognition.
  This position may be responsible for maintaining the security and integrity of critical infrastructure, as defined in Section 113.001(2) of the Texas Business and Commerce Code and therefore may require routine reviews and screening. The ability to satisfy and maintain all requirements necessary to ensure the continued security and integrity of such infrastructure is a condition of hire and continued employment.
  It is the policy of The University of Texas MD Anderson Cancer Center to provide equal employment opportunity without regard to race, color, religion, age, national origin, sex, gender, sexual orientation, gender identity/expression, disability, protected veteran status, genetic information, or any other basis protected by institutional policy or by federal, state, or local laws unless such distinction is required by law.

Additional Information

• Requisition ID: 184078
• Employee Status: Regular
• Minimum Salary: US Dollar (USD) 0
• Midpoint Salary: US Dollar (USD) 0
• Maximum Salary : US Dollar (USD) 0
• FLSA: exempt and not eligible for overtime pay
• Work Location: Hybrid Onsite/Remote

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