Senior Patient Recruitment and Retention Lead (CONTRACT)

The Organization

What's happening at Entrada Therapeutics? Entrada is a clinical-stage biopharmaceutical company aiming to transform the lives of patients by establishing a new class of medicines that engage intracellular targets that have long been considered inaccessible. Through proprietary and versatile approaches, Entrada is advancing a robust development portfolio of genetic medicines for the potential treatment of neuromuscular and inherited retinal diseases, among others. Our lead oligonucleotide programs are in development for the potential treatment of people living with Duchenne muscular dystrophy (DMD) who are exon 44, 45, 50 and 51 skipping amenable. Entrada has partnered with Vertex Pharmaceuticals to develop a clinical-stage program, VX-670, for myotonic dystrophy type 1 (DM1).

2026 represents a catalyst-rich period for Entrada. We expect multiple clinical data readouts as we advance several DMD programs across the U.K., EU, and U.S. By year-end 2026, we anticipate four clinical-stage programs in our DMD franchise (ENTR-601-44, ENTR-601-45, ENTR-601-50, and ENTR-601-51). These programs are complemented by the ongoing clinical progress of our DM1 collaboration with Vertex (VX-670).

We are a tight-knit team of experts and leaders in both therapeutic development and rare diseases and are excited to grow and attract colleagues who are ready to join a high-energy, dedicated team that likes to get things done and dramatically improve the lives of patients and their families.

The Perfect Addition to Our Team

You are a seasoned leader in the pharmaceutical industry who is eager to shape and implement patient recruitment and retention strategies for clinical trials. You are well organized and collaborative, able to work seamlessly with teams to drive our clinical activities. You thrive in a fast-paced environment, juggling priorities, and stepping in wherever needed. With a proven track record in scaling operations within biotech or pharmaceutical settings, you are a results-driven problem solver who efficiently connects problems with solutions.
The Opportunity

The Patient Recruitment & Retention Contractor will be responsible for development and execution of Entrada's clinical trial recruitment and retention, bringing proven expertise in building and optimizing clinical trials, feasibility, patient recruitment, and regulatory compliance. This role reports to the SVP, Clinical and Business Operations & Quantitative Science, and will support ongoing and new global rare disease trials.
Responsibilities

• In partnership with study teams, develop and oversee global patient recruitment and retention strategies across all clinical programs, ensuring alignment with portfolio timelines, program priorities, and corporate development goals.
• Drive execution of integrated feasibility strategies, including landscape analysis, enrollment modeling, and site capability assessments to inform protocol optimization and accelerate trial start up.
• Ensure alignment between ongoing trial feasibility efforts and patient recruitment and retention strategies through effective vendor partnerships.
• Establish and monitor enrollment KPIs and recruitment progress; providing regular progress reporting to Clinical Operations leadership and study teams as well as senior leadership, implementing course corrections when needed.
• Serve as subject matter expert on global regulatory expectations (FDA, EMA) for diversity and inclusive research practices, supporting cross-functional teams on compliance and strategies and staying up-to-date on recruitment technologies.
• Bring the patient voice and experience into the patient recruitment and retention strategy and related materials.
• Proactively identify risks to enrollment timelines, implementing mitigation strategies where necessary and communicating said risks to study leadership teams.
• Provide insights to program-level performance of patient recruitment vendors and digital outreach agencies where needed.

The Necessities

At Entrada, our passion for science, our devotion to patients and our values drives our behavior:

• Humanity - We genuinely care about patients and about one another.
• Tenacity - We are relentless and persistent in the pursuit of developing therapies for patients.
• Creativity - We are creative problem solvers.
• Collaboration - We are more than the sum of our parts.
• Curiosity - We have a growth mindset and push conventional thought and theory.

To thrive on our team, you will need to come with:

• Bachelor's degree in life sciences, business, or a related field; advanced degree preferred.
• 10+ years of progressive leadership experience in clinical operations or related areas, with at least 6 + years focusing on study recruitment, study diversity, and patient engagement.
• Experience working with rare disease patient populations across global regions.
• Direct experience implementing and executing challenging patient recruitment and retention strategies for late-phase studies.
• Forward-thinking and creative with high ethical standards.
• Ability to work in a fast-paced professional environment with changing priorities and business needs.
• Strong problem-solving, multitasking, and organizational skills, with the ability to work independently and stay self-directed.
• This is a US based remote position with preference given to local New England based candidates. This role will require minimum monthly or quarterly travel to the Entrada Therapeutics Headquarters located in Boston, MA.#LI-JF1 #LI-Remote

Equal Opportunity Employer

Entrada Therapeutics is an equal opportunity employer. Qualified candidates will receive consideration for employment without regard to race, color, religion, national origin, gender, sexual orientation, gender identity or expression, age, mental or physical disability, and genetic information, marital status, citizenship status, military status, protected veteran status or any other category protected by law.
Third Party Staffing Agencies

Entrada does not accept unsolicited resumes from any source other than directly from candidates. For the protection of all parties involved in the recruiting process, resumes will only be accepted from recruiters/agencies if a signed agreement is in place at the inception of the recruiting effort and authorized for a specified position. Unsolicited resumes sent to Entrada from recruiters/agencies do not constitute any type of relationship between the recruiter/agency and Entrada and do not obligate Entrada to pay fees if we hire from those resumes.
Privacy Statement

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