Postdoctoral Associate- Xiao Wang Lab

About the Position The Xiao Wang group at the Broad Institute of MIT and Harvard is looking for an exceptional and energetic postdoctoral associate to join a rapidly growing, multidisciplinary research effort focused on developing and applying molecular and imaging tools (e.g., in situ RNA sequencing) to understand the complexity of biological systems. This postdoctoral position offers an exciting opportunity to develop new sequencing and imaging strategies for multiscale brain mapping in a vibrant and interdisciplinary environment. The candidate will collaborate with team members from diverse backgrounds—chemistry, biophysics, genomics, and neuroscience—and will have opportunities to interact with research teams within the Broad Institute as well as the broader MIT and Harvard community and affiliated hospitals across Boston. Minimum Qualifications 0+ years of postgraduate experience. PhD in physical or biological science, neuroscience, bioengineering, or related disciplines. Hands‑on experience with microscopy, molecular biology, animal models, and gene delivery vectors (e.g., AAV and lentivirus). Self‑motivated, creative, persistent, responsible, attention to detail, good analytical and problem‑solving skills, and a fast learner. Responsibilities Fluorescence microscopy (living or preserved samples), electron microscopy (SEM/TEM), or correlative light and electron microscopy (CLEM). Design and generate AAV or lentivirus vectors for expression of transgenes in desired subcellular locations and desired cell populations. Design, characterize, and engineer RNA—including in situ hybridization, microarray, gel electrophoresis, HPLC, SELEX, NGS, and single‑cell RNA sequencing; study RNA structure, modification/editing, localization, RNA‑protein complexes, non‑coding RNAs, synthetic RNAs, etc. Conduct scientific investigations in neuroscience or other biological systems at molecular (nucleic acids, proteins, lipids) and cellular (subcellular organelles, granules, membranes, synapses) levels. The expected base pay range for this position is based on a 40‑hour per week schedule. Broad provides pay ranges representing its reasonable and good faith estimate of what the organization reasonably expects to pay for a position at the time of posting. Actual compensation will vary based on factors including but not limited to relevant skills, experience, education, and other factors permissible by law. From day one, this role offers a comprehensive total rewards package, including medical, dental, vision, life, and disability insurance; a 401(k) retirement plan; flexible spending and health savings accounts; at least 13 paid holidays; winter closure; paid time off; parental and family care leave; and an employee assistance program, among other Broad benefits. The Broad Institute is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, national origin, religion, age, color, sex, disability, protected veteran status, or any other characteristic protected by local, state, or federal laws, rules, or regulations. Should you need a reasonable accommodation to complete the application or interview process, please contact View email address on click.appcast.io for assistance. #J-18808-Ljbffr