Sign up to access all features of our service.
  • Job search
  • Favorites
  • Create a CV
    New
  • Salaries
  • Subscriptions

Advanced Practice Registered Nurse - APRN

MLee Healthcare Staffing and Recruiting, Inc

Advanced Practice Registered Nurse - APRNEmbrace Your Future — Begin the Next Chapter as an Advanced Practice Registered Nurse in Vibrant Sioux FallsIn the world of healthcare, true impact is measured not merely in statistics but in the lives transformed and futures brightened. As an Advanced Practice Registered Nurse (APRN), you're already aware of the profound difference that a timely diagnosis, an empathetic conversation, and a customized care plan can make. Now, picture channeling that expertise into a thriving community nestled in the stunning landscape of Sioux Falls, where healthcare innovation meets a lifestyle filled with connection and joy.This opportunity is more than just a job — it's a chance to become part of a mission-driven team that values your contributions, amplifies your voice, and transforms patients into an extended family. Whether your passion lies in primary practice, family medicine, or a specialized area, you will find your leadership and clinical autonomy respected and encouraged.When your working hours wrap up, Sioux Falls welcomes you with tranquil parks, stunning waterfalls, and a lively arts scene. If you've been yearning for a position that nurtures your sense of purpose and ignites your passion, this is your moment.Your ResponsibilitiesConducting detailed patient evaluations, ordering essential diagnostic tests, and creating individualized care plansDiagnosing and managing acute, episodic, or chronic conditions, collaborating with physicians or practicing independently when credentialedProviding education to patients and families regarding prevention strategies, wellness, and disease managementPrescribing medications and treatment regimens within your defined scopeEngaging in follow-up care and management for chronic conditionsCollaborating with interdisciplinary teams to deliver comprehensive, patient-centered careDocumenting patient encounters accurately in electronic medical records (EMR)Educational QualificationsMaster of Science in Nursing (MSN) or Doctor of Nursing Practice (DNP)Graduation from an accredited Nurse Practitioner programCertifications NeededCurrent Nurse Practitioner licensure in South DakotaNational certification as a Family Nurse Practitioner (FNP-C, AANP or ANCC) or equivalent specialtyBasic Life Support (BLS) and Advanced Cardiovascular Life Support (ACLS) certification (or capability to obtain within 90 days)Key Skills That Make You ShineRobust clinical knowledge paired with a compassionate approach to patient careExceptional communication abilities with patients, families, and colleaguesFlexibility in fast-paced, patient-focused environmentsProficient in EMR platforms and well-versed in telehealth technologiesA collaborative spirit and dedication to evidence-based practiceWhat You'll Appreciate About This PositionFull-time or flexible scheduling availableDiverse patient demographics across age ranges and medical conditionsA supportive environment that enables you to prioritize patient careOngoing professional development and specialty certification opportunitiesAccess to cutting-edge technology, diagnostics, and telemedicine resourcesA collaborative, mission-driven workplace cultureAttractive benefits package including health, dental, and vision insurance, paid time off, and continuing education fundsWhy Sioux Falls is Your Perfect HomeVisualize waking up to the melodious sounds of nature as you start your day with a refreshing run along the picturesque banks of the Big Sioux River. After indulging in a delightful breakfast at a local café, you embark on your shift, knowing that your medical expertise truly makes a difference. As your day comes to a close, you unwind while exploring a vibrant local art scene, dining at diverse eateries, or enjoying live performances at intimate venues with friends who feel more like family.This is the essence of Sioux Falls — a spirited community where healthcare is more than just a service, but a tapestry of human connection. With a flourishing economy, a culturally rich atmosphere, and a consistently high quality of life, this region has something for everyone. South Dakota boasts no state income tax, allowing you to keep more of your hard-earned money. Whether you're passionate about outdoor adventures, cultural excursions, or simply enjoying time with loved ones, you'll find a balanced lifestyle that complements your aspirations both professionally and personally.From the captivating waterfalls and scenic trails to the vibrant markets and creative gatherings, Sioux Falls is where people come together — for their families, their communities, and their vocations.As an Advanced Practice Registered Nurse, you will play a vital role in this dynamic ecosystem, supporting patients who become cherished friends and neighbors.Your Expertise and Our Vision — A Perfect Harmony.We are looking for Advanced Practice Registered Nurses who are not just content with treating patients — they wish to elevate care, promote health equity, and cultivate meaningful relationships. If your drive is fueled by passion and commitment, and you are poised to make a difference in a community that upholds both excellence and balance, we invite you to join our team.Apply now and discover a position that respects your expertise, fosters your development, and welcomes you home to Sioux Falls.

Vacancy posted 2 days ago
Similar jobs that could be interesting for youBased on the Advanced Practice Registered Nurse - APRN in Sioux Falls, SD vacancy
  •  ...accredited educational program in specific area of advanced practice. Masters degree, Doctor of Nursing Practice (DNP), or Doctor of Philosophy (Ph.D.) preferred...  ...unencumbered licensure to practice as a Certified Registered Nurse Anesthetist (CRNA) from the State Board of... 
    Suggested
    Full time
    Part time
    Work from home
    Shift work

    Sanford Health

    Sioux Falls, SD
    3 days ago
  •  ...Job TitleCertified Registered Nurse Anesthetist (CRNA)DutiesThe VA Midwest Health Care Network advocates for a Whole Health System of care in each of the Medical Centers. This is an approach to healthcare that empowers and equips people to take charge of their health... 
    Suggested

    US Department of Veterans Affairs

    Sioux Falls, SD
    5 days ago
  •  ...to medical staff approved protocol and acceptable standards of practice.Provides medical services and health education to patients and...  ..., License/Certification, or Work Experience:Certified Neonatal Nurse Practitioner (NNP) - National Certification Corporation (NCC) An... 
    Suggested
    Full time
    Part time
    Work experience placement
    Shift work
    Weekend work
    Day shift
    Afternoon shift

    Avera McKennan

    Sioux Falls, SD
    5 days ago
  •  ...The Avera Behavioral Health Center-Sioux Falls is seeking a skilled RN to deliver compassionate nursing care in an adolescent and child unit. You will develop care plans, monitor patient conditions, and coordinate with a multidisciplinary team to support families. The... 
    Suggested
    Relocation package
    Night shift
    Afternoon shift

    Avera McKennan

    Sioux Falls, SD
    3 days ago
  •  ...approved protocol and acceptable standards of practice. Provides medical services and health...  ..., Or Work Experience Certified Neonatal Nurse Practitioner (NNP) - National...  ...state based on job assignment Upon Hire and Registered Nurse (RN) - Board of Nursing An active... 
    Suggested
    Work experience placement
    Relief
    Shift work
    Night shift
    Afternoon shift

    Sioux Center Health

    Sioux Falls, SD
    3 days ago
  •  ...Job Description\n Premier Medical Staffing Services is seeking a travel nurse RN Pediatrics for a travel nursing job in Sioux Falls, South Dakota.Job Description & Requirements\n \n Specialty: Pediatrics\n Discipline: RN\n Start Date: 09/28/2026\n Duration: 12 weeks\n... 
    Daily paid
    Contract work
    Zero hours contract
    Shift work

    Premier Medical Staffing Services

    Sioux Falls, SD
    1 day ago
  • $2,629 - $2,682 per month

     ...capable of managing frequent interactions with the public and customers and meeting deadlines under pressure. Comfortable working under occasional close supervision or independently. Sensory Skills – keen visual understanding and practical communication abilities.... 
    Weekly pay
    Shift work

    CrossMed Healthcare Staffing

    Sioux Falls, SD
    5 days ago
  • $2,722 per week

    American Traveler Staffing Professionals is seeking an experienced RN for a Cardiac Progressive Care Unit position requiring Cardiac Step Down experience and vasoactive drip management. The role features 12-hour shifts with day/night rotation in a 6-week block, 36 hours...
    Shift work
    Night shift

    American Traveler

    Sioux Falls, SD
    4 days ago
  •  ...Avera Cancer Institute in Sioux Falls is seeking a PRN Registered Nurse to join a multidisciplinary team. You will review prescriptions, communicate the care plan, and coordinate with healthcare providers to support patients and families. The role emphasizes developing... 
    Relief

    Avera McKennan

    Sioux Falls, SD
    4 days ago
  • $2,260 per week

     ...CoreMedical Group is seeking a travel nurse RN ICU - Intensive Care Unit for a travel nursing job in Sioux Falls, South Dakota....  ...2 hours ~ Employment Type: Travel Client in SD seeking Registered Nurse: Critical Care/ICU for the following shift(s): Nights... 
    Hourly pay
    Weekly pay
    Permanent employment
    Contract work
    Locum
    Interim role
    Zero hours contract
    Shift work
    Night shift

    CoreMedical Group

    Sioux Falls, SD
    3 days ago
  • $32.5 - $48.5 per hour

     ...Registered Nurse (RN) - DialysisLocation: Avera Dialysis-Sioux FallsWorker Type: RegularWork Shift: Rotating days/evenings/nights/weekends...  ...dialysis Dialysis treatment is provided within the scope of nursing practice. Home dialysis nurses provide major portions of self- care... 
    Work experience placement
    Relocation package
    Shift work
    Night shift
    Rotating shift
    Afternoon shift

    Avera Health

    Sioux Falls, SD
    1 day ago
  •  ...Registered NurseCareers With Purpose As one of the largest not-for...  ...joining our team of over 18,000 nurses. Our workplace culture...  ...with people who value your advancement and help you find your niche...  ...Board of Nursing where the practice of nursing is occurring and/... 
    Full time
    Part time
    Work from home
    Relocation package

    Sanford Health

    Sioux Falls, SD
    5 days ago
  •  ...Avera Health is seeking an RN to deliver nursing care at the Avera Cancer Institute in Sioux Falls. You will work PRN with day/evening/weekend/holiday shifts, providing patient-centric care and collaborating with a multidisciplinary team. Responsibilities include creating... 
    Relief
    Weekend work
    Day shift
    Afternoon shift

    Avera Health

    Sioux Falls, SD
    3 days ago
  • $2,399.6 per month

    Registered Nurse - Oncology - Travel | Sioux Falls, South Dakota Estimated Weekly Pay: $2399.60 Start Date: 09/28/2026 | Duration: 13 Weeks Shift: 5 x 8hr Days Job Details AHS Staffing is seeking a qualified Travel - Registered Nurse - Oncology in Sioux... 
    Hourly pay
    Weekly pay
    Daily paid
    Flexible hours
    Shift work

    AHS Staffing

    Sioux Falls, SD
    4 days ago
  •  ...shift schedule at 36 hours per week Every other weekend and every other holiday rotation required 13-week assignment lengthProvide nursing care to stepdown‑level cardiopulmonary patients in an acute care setting 8 hours of orientation provided Accepts local candidates within... 
    Daily paid
    Local area
    Night shift
    Weekend work

    American Traveler

    Sioux Falls, SD
    1 day ago
  • $40 - $42 per hour

     ...Licensed Practical Nurse (LPN)Interim HealthCare is America's leading provider of home care and healthcare staffing. As a family owned, women owned, and veteran owned business, we have been in Sioux Falls the past 34+ years, Brookings for the past 9+ years, and Fargo for... 
    Hourly pay
    Weekly pay
    Full time
    Contract work
    Part time
    Interim role
    Relief
    Local area
    Shift work
    Night shift

    Interim Healthcare Staffing

    Sioux Falls, SD
    1 day ago
  •  ...Job Description\n Host Healthcare is seeking a travel nurse RN Oncology for a travel nursing job in Sioux Falls, South Dakota.Job Description & Requirements\n \n Specialty: Oncology\n Discipline: RN\n Start Date: 09/28/2026\n Duration: 13 weeks\n 36 hours per week\n Shift... 
    Zero hours contract
    Shift work

    Host Healthcare

    Sioux Falls, SD
    3 days ago
  •  ...RN - DIALYSISA Dialysis Registered Nurse, (RN) is a nurse who specializes in caring for patients undergoing hemodialysis or peritoneal dialysis, both of which are life-saving procedures for those with severely impaired kidney function. He/she is responsible for the common... 

    Care Career

    Sioux Falls, SD
    4 days ago
  •  ...Registered NurseAs one of the largest not-for-profit health systems...  ...joining our team of over 18,000 nurses. Our workplace culture...  ...with people who value your advancement and help you find your niche...  ...Board of Nursing where the practice of nursing is occurring and/... 
    Full time
    Part time
    Work from home
    Relocation package
    Rotating shift

    IntelyCare

    Sioux Falls, SD
    2 days ago
  •  ...work and live, bring your expertise to Avera's patient-centered and service-oriented environment. Join us in providing compassionate nursing care in a true team environment — and work alongside expert physicians and surgeons. At Avera, we provide nationally recognized... 

    AMN Healthcare

    Sioux Falls, SD
    4 days ago
  • $10k

     ...eligible for a $10,000 sign on bonus.Student Loan Repayment: This Registered Nurse (RN) position may be eligible for Avera's Student Loan...  ...professional nursing care under the direction of the provider.Licensed Practical Nurse (LPN) - Board of Nursing An active license in the... 
    Full time
    Part time
    Work experience placement
    Work at office
    Relocation package
    Shift work
    Night shift
    Weekend work
    Day shift

    Avera Health

    Sioux Falls, SD
    1 day ago
  • $40 - $42 per hour

     ...wish to make a difference in their community, through strong leadership and dedication to the health care field! Our Licensed Practical Nurses (LPNs) enjoy: Licensed Practical Nurse (LPN) Pay Rate: $40-$42+ per hour - PAID WEEKLY! PRN / Part-Time / Full-Time Contract Licensed... 
    Hourly pay
    Weekly pay
    Full time
    Contract work
    Part time
    Interim role
    Relief
    Local area
    Shift work
    Night shift

    Interim HealthCare

    Sioux Falls, SD
    5 days ago
  •  ...Sign-on Bonus available for eligible applicants!Job SummaryThe Registered Nurse (RN) is responsible for utilizing the nursing process (...  ...works hard to develop curricula that integrates evidence-based practices and engages with partners across our organization to provide... 
    Full time
    Part time
    Work from home
    Relocation package
    Night shift

    Sanford Health

    Sioux Falls, SD
    4 days ago
  • $1,000 per month

     ...Medical Compliance ItemsTravel reimbursement available up to $1000DescriptionWe're looking for Dialysis RNs for an immediate travel nurse opening in Sioux Falls, SD. The right RN should have 1-2 years recent acute care experience. Read below for more requirements. As a... 
    Permanent employment
    Temporary work
    Immediate start

    TotalMed Staffing

    Sioux Falls, SD
    2 days ago
  •  ...Registered Nurse Progressive Care UnitSkyBridge Healthcare is currently seeking Registered Nurse with Progressive Care Unit experience for a 13-week contract in Sioux Falls, SD. SkyBridge Healthcare is a premier staffing firm dedicated to matching outstanding talent with... 
    Weekly pay
    Full time
    Contract work
    Relocation package

    Skybridge Resources

    Sioux Falls, SD
    2 days ago
  •  ...Avera McKennan in Sioux Falls is seeking a Registered Nurse to provide professional nursing care to patients and families in a multidisciplinary setting. You will administer medications, support procedures, and coordinate patient care with physicians and our healthcare... 

    Avera McKennan

    Sioux Falls, SD
    5 days ago
  • $75k

     ...As a critical care nurse and officer on the U.S. Army or Army Reserve health care team, you manage the care of our Soldiers and their families, making immediate decisions and applying your critical technical and thinking skills when they need it most. You'll work in state... 
    Permanent employment
    Part time
    Immediate start
    Worldwide
    Flexible hours

    U.S. Army 3rd Medical Recruiting Battalion

    Sioux Falls, SD
    2 days ago
  •  ...Job Description\n TNAA TotalMed RN is seeking a travel nurse RN Oncology for a travel nursing job in Sioux Falls, South Dakota.Job...  ...number of details while working under pressure.\n Implement best practice treatment protocols in a variety of settings.\n Oncology Travel... 
    Weekly pay
    Permanent employment
    Zero hours contract
    Relief
    Local area
    Immediate start
    Shift work

    TNAA TotalMed RN

    Sioux Falls, SD
    1 day ago
  • $27.75 - $46.25 per hour

     ...Registered Nurse (RN) - OncologyLocation: Avera Cancer Institute-Sioux FallsWorker Type: RegularWork Shift: Day Shift (United States of America...  ...(RN) - Board of Nursing An active license in the state of practice Upon Hire andONS Fundamentals Provider Card - Oncology... 
    Work experience placement
    Shift work
    Day shift

    Avera Health

    Sioux Falls, SD
    5 days ago
  • $32.5 - $48.5 per hour

     ...Director/Nephrologist, patients, families, other nursing staff and ancillary departments.Maintains...  ...do not cause undue hardship to the employer.Registered Nurse (RN) - Board of Nursing An active license in the state of practice Upon Hire1-3 years nursingPreferred... 
    Work experience placement
    Relocation package
    Monday to Friday
    Shift work
    Night shift

    IntelyCare

    Sioux Falls, SD
    5 days ago

Do you want to receive more vacancies?

Subscribe and receive similar vacancies to Advanced Practice Registered Nurse - APRN. Be the first to apply!