Lead Scientist, Immune Cell Depletion Discovery
AbbVie
About AbbVie AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at Follow @abbvie on LinkedIn, Facebook, Instagram, X and YouTube. Company Description About AbbVie AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at Follow @abbvie on LinkedIn, Facebook, Instagram, X and YouTube. Job Description The Immunology Discovery Therapeutic Area is seeking an accomplished and experienced Scientist to lead the Immune Cell Depletion Group within the Immune Reset Therapeutics Discovery team based in Cambridge MA. In this role you will lead a multidisciplinary team of highly talented scientists with experimental, technical and scientific expertise in cellular depletion approaches. The candidate should have a demonstratable track-record in this scientific discipline alongside a strong knowledge of preclinical drug discovery spanning target discovery / validation through to GLP toxicology phases. The ability to effectively collaborate and deliver results across multi-disciplinary line functions both internally and with external leading experts is required. Proven expertise leading preclinical drug discovery programs leveraging cellular depletion approaches in autoimmune disease is an advantage. Applicants should have a strong publication record and have proven experience in leading (managing) & developing bench-based scientists. Key Responsibilities: Lead the Immune Cell Depletion Group within Immunology Discovery. Responsible for refining the strategy and biology focus within this area to support and advance the portfolio Provide biology expertise to internal teams that helps pave the way for next-generation therapies that leverage cell depletion approaches to develop next generation therapies for rheumatological, dermatological, gastroenterological and respiratory diseases Key member of the Immune Reset Therapeutics Discovery Leadership Team, to support advancement of Immune Tolerance biology into the drug discovery pipeline Proven experience in managing, growing and developing highly talented scientists Drive performance by Leading from the Bench. Including the ability to design and execute on key experiments to inform decision-points (GO / NO-GO) at critical stages of projects Proven track record of leading and influencing early to late-stage discovery programs Deep immunology expertise, with emphasis on understanding how cell depletion approaches can potentially raise the treatment ceiling for patients with autoimmune disease Help develop and execute a strategy in alignment with functional goals and key scientific objectives in discovery immunology research. Highly collaborative, team-oriented, and considerate of the needs of others Strong interpersonal skills and ability to collaborate with diverse groups within the organization and external partners. Highly organized & self-directed, capable of leading multiple complex research programs in parallel. Excellent written and verbal communication is required as well as critical evaluation and data-driven decision making. Provide expert advice and share knowledge with direct reports, peers, and senior leadership Establish and manage external collaborations with leading research labs around the world. Includes attendance / presentation at conferences and submission of publications. Qualifications 18 +(BS), 16+ (MS), or 10+ (PhD) years of related work experience in academia, biotech or pharma Extensive experience in Immunology drug discovery within a high-caliber research environment with 6+ years of related work experience in biotech or pharma Ability to create an inclusive environment where diverse ideas, viewpoints and backgrounds are valued. Willingness and ability to lead inclusively and demonstrate a commitment to listen and consider all points of view Ability to work, influence, lead and deliver results in cross-functional teams Excellent written, presentation and interpersonal communication skills. Ability to be effective in a highly collaborative environment. Key AbbVie Competencies: Builds strong relationships with peers and cross functionally with partners outside of the team to enable high performance. Learns fast, grasps the “essence” and can change course quickly where indicated. Raises the bar and is never satisfied with the status quo. Additional Information Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of thisposting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location,and we may ultimately pay more or less than the posted range. This range may be modified in the future. We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees. This job is eligible to participate in our long-term incentive programs. Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission,incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless anduntil paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law. AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled. US & Puerto Rico only - to learn more, visit US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more: #J-18808-Ljbffr AbbVie
- ...Facebook , Instagram , X and YouTube. Job Description The Immunology Discovery Therapeutic Area is seeking an accomplished and experienced Scientist to lead the Immune Cell Depletion Group within the Immune Reset Therapeutics Discovery team based in Cambridge...SuggestedFull timeWork experience placementLocal area
- BioSpace in Cambridge, MA is seeking an experienced Scientist to lead the Immune Cell Depletion Group. This role demands expertise in Immunology drug discovery and will involve managing a team of skilled scientists. The candidate will drive performance by designing key...Suggested
- ..., Inc. in Boston seeks a senior drug discovery biologist to lead hands-on biology within our Discovery... ...initial lead strategies, focusing on cell-based assays and GPCR biology. Collaborating... ...biology strategy, mentor junior scientists, and communicate findings across...Suggested
- ...looking for a motivated Sr. Research Associate/Associate Scientist to advance iPSC-derived immune cell therapies. In this role, you will perform iPSC... ...and vital data analysis within a collaborative drug discovery team. The ideal candidate holds a Bachelor/Master in...Suggested
$80.3k - $131.1k
...highly motivated and innovative Senior Associate Scientist to join our discovery research team at Regeneron Cell Medicines. You will be performing immunological functional... ...immunological functional assays to assess immune cell activation, anti‑tumor cytotoxicity,...Suggested$80.3k - $131.1k
...highly motivated and innovative Senior Associate Scientist to join our discovery research team at Regeneron Cell Medicines. You will be performing immunological functional... ...immunological functional assays to assess immune cell activation, anti‑tumor cytotoxicity,...$134.89k - $202.34k
...AI Expert, Immunology Cell Therapy Discovery AstraZeneca, a global leader in... ...expert (Associate Principal Scientist or Principal Scientist level... ...initiatives with a dual emphasis on immune mediated diseases and... ...innovation. The role will lead innovation by integrating AI...Temporary work- A biotechnology startup in Boston is looking for a Principal Scientist to lead CHO-based cell line development. In this role, you will conduct and supervise innovative cell line development for biologics, manage a team of scientists, and represent the company in external...
$145k - $190k
Dormont Manufacturing Co is looking for a Senior or Principal Scientist to join their Biologics Cell Line Development team in Boston, MA. You will lead CHO cell line development processes and manage a team of junior scientists, contributing to innovative biotherapeutics...Flexible hours- Flagship Pioneering is seeking a Senior Scientist in Cambridge, MA, to join the Platform Discovery and Engineering team. This role focuses on the discovery and development of therapeutic proteins, especially monoclonal antibodies, through innovative phage display workflows...
- The Antibiotic Discovery Center at Northeastern University seeks an Associate Research Scientist to lead natural product-based antibiotic discovery efforts. You will guide multidisciplinary teams in microbiology, biochemistry, and analytical chemistry to identify and characterize...
$120 - $140 per hour
A leading provider in pharmaceutical research is seeking a Senior Scientist to act as a DMPK project representative. The role involves providing scientific leadership in drug discovery projects, focusing on small molecule candidates. The ideal candidate will have extensive...Hourly payContract work- Commonwealth Sciences, Inc. is seeking a scientist to lead the development, optimization, and qualification of cell‑based potency assays for cell therapy products. You will design functional assays and support GMP-related activities to characterize products and assess...
- ...for a high-impact Computational Chemist to join the integrated discovery team. This role involves combining physics-based modeling,... ...prioritizing compounds, collaborativing with interdisciplinary scientists, and designing workflows to optimize discovery cycles. Superluminal...
- ...biochemistry expert for a full-time, hybrid role based in Boston, MA. The ideal candidate will lead the design and implementation of biochemical assays, supporting drug discovery efforts with a collaborative team. This position requires a Ph.D. with relevant experience in...Full time
$144.8k - $227.9k
...Description Associate Principal Scientist, Discovery Immunology Job... ...patients worldwide through leading edge research, scientific breakthroughs... ...equivalent) in immunology, cell biology or related... ...with extensive knowledge of immune-mediated diseases across Gastroenterology...For contractorsLocal areaWorldwideRelocationVisa sponsorshipFlexible hoursShift work- Real Staffing in Cambridge, MA is seeking a qualified candidate for a position focusing on mammalian cell culture and development of cell-based assays. The role entails using liquid handling equipment and maintaining high-capacity cell culture systems, alongside delivering...Casual work
- Predicta Biosciences is seeking a Senior R&D Scientist to lead assay development for NGS technologies, including whole genome sequencing and single-cell RNA-seq. The role focuses on tumor and immune cell characterization and collaboration with wet-lab and computational...
- ...Paid time off Stock options plan Scientist/Senior Scientist, Biology Lead - Kidney Experience About the Role... ...research platforms that enable target discovery, mechanistic validation,... ...PhD in Nephrology, Renal Biology, Cell Biology, Molecular Biology, Pharmacology...
- ...to come join our vibrant team and help us lead the way into a new gene therapy era.... ...ROLE ON THE TEAM We are seeking a Contract Scientist I with strong cell and molecular biology experience to join the RNA Therapeutic Discovery Team. In this contractor role, the selected...Contract workFor contractors
$151k - $170k
Overview Senior Scientist - Genome Editing, Genomic Sciences and Target Discovery. We are seeking an enthusiastic and highly motivated Senior Scientist to join the... ...including PCR, NGS, immunohistochemistry, and single-cell sequencing, to confirm CRISPR-mediated gene...Local area- ...accomplished in vitro biologist to join our Discovery Neuroscience organization. This scientist will contribute to early discovery... ...support in vitro assay execution, cell culture‑based model development,... ...of experimental workflows. Lead assay optimization efforts,...Temporary workLocal area
- ...based in Cambridge, Massachusetts. This BS/MS level scientist will play a critical role in the discovery and characterization of therapeutic antibodies. The successful... ...team. A strong background in molecular biology, cell culture, and flow cytometry is essential. Join us in...
- ...seeking a knowledgeable professional for their Upstream Antibody Discovery team in Boston, Massachusetts. The ideal candidate will have... ...antibody discovery workflows, including hands-on skills in mammalian cell culture and wet lab techniques. The role requires coordinating...
$90k - $200k
...methods for deep quantitative analysis of cell and tissue total proteomes as well as... ...is generated for the progression of drug discovery projects. Skills and experience you’ll bring... ...fast‑paced, team‑oriented environment. Lead from the lab for activities include hit validation...- Responsibilities Lead the development, optimization, and qualification of cell-based potency assays that evaluate the biological... ...partners. Mentor junior scientists and contribute to the continuous... ...assays such as cytokine secretion, immune cell activation, cytotoxicity,...Contract work
- ...team seeks a highly motivated senior associate scientist to apply NGS and emerging genomic technologies in drug discovery and preclinical development. The role covers design... ...genomics approaches, including single-cell and spatial transcriptomics. #J-18808-Ljbffr Pfizer...
- ...in vitro biologist to contribute to early discovery in neuroscience, with a focus on Parkinson's disease. You will perform cell-based assays and model development to generate... ...program decisions. You will work with scientists across discovery biology and translational...
- ...seeking a motivated and talented Scientist to join our Oncology Research... ...environment alongside leading scientists in the field of oncology... ..., oncology drug discovery and development. Execute a variety... ...and manipulation of 2D and 3D cell cultures, including spheroids...Full timeContract work
- ...Senior Scientist, Cell Therapy Discovery Waltham, MA, USA AstraZeneca is a science-led biopharmaceutical company focused on transforming patient... ...-matrixed environment. Role overview You will lead and execute in vitro functional assays, with preferred...
Do you want to receive more vacancies?
Subscribe and receive similar vacancies to Lead Scientist, Immune Cell Depletion Discovery. Be the first to apply!
- scientist antibody discovery Cambridge, MA
- protein scientist Cambridge, MA
- lead scientist Cambridge, MA
- applied sports scientist Cambridge, MA
- deep learning scientist Cambridge, MA
- bioinformatic ngs scientist Cambridge, MA
- lab scientist Cambridge, MA
- principal scientist Cambridge, MA
- molecular biology scientist Cambridge, MA
- senior analytical scientist Cambridge, MA

