Senior Software Engineer, .NET

Summary As a public and profitable company, we have ambitious plans to scale and enhance our products and services. We’re looking for Senior Software Engineers who can design and deliver high‑quality solutions, collaborate effectively across teams, and contribute to meaningful improvements in our platform. Senior engineers at GeneDx focus on owning significant components, contributing to architectural discussions, and delivering reliable, well‑tested software. Job Responsibilities As a Senior Software Engineer, you'll work on advancing our technology platform and building software products that make a meaningful impact. You will contribute to medium‑ to large‑scale technical efforts, mentor junior engineers, collaborate with cross‑functional partners, and deliver robust, scalable solutions aligned with our business objectives. Day to day tasks may include: Dive into unfamiliar code to troubleshoot or add a new feature Participate in feature development of larger projects Technically lead smaller projects Participate in Support tasks, including off‑hours and weekend on‑call rotations. Propose technical designs, considering standard patterns, tradeoffs, and maintainability Provide thorough and meaningful code reviews Work with legacy as well as novel code bases Prototype, develop, and debug new features Implement and maintain DevOps cloud patterns People Manager No Education, Experience, And Skills Proficiency in at least 3 software languages, with a demonstrated ability to quickly learn new ones as needed. 6+ years of software engineering experience, including significant experience in: .NET Framework and .NET (Core/6+), C# SQL Server (schema design, performance tuning, migration strategies) Message queues, ideally MSMQ in production Demonstrated experience in modernizing legacy applications into cloud‑native microservices and event‑driven architectures. Strong understanding of troubleshooting and maintenance of systems running on a Windows platform Ability to understand system performance metrics and translate them into actionable improvement tasks 3+ Experience with front‑end applications using modern frameworks (React highly desired, but Vue, or Angular are acceptable). Experience with data modeling using multiple database and storage types. 5+ years experience designing and deploying resilient and scalable large scale and distributed services in the cloud using Docker and Kubernetes (e.g. AWS, GCP, Azure, OCI). Applied knowledge of multiple architectural paradigms. Bonus points for: Prior healthcare / health tech experience, or experience in other regulated industries, particularly with data privacy and compliance requirements. Certificates, Licenses, Registrations None Physical Demands This is a sedentary role requiring prolonged periods of sitting while working at a computer. Physical demands include: Sitting for extended periods (up to 8 hours per day) Repetitive use of hands and fingers for typing and mouse operation Visual acuity for reading computer screens and documents Ability to communicate effectively via phone and video calls Occasional lifting of up to 10 pounds (office supplies, equipment) Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions of this position. Work Environment This is a fully remote position. The employee will work from a home office or other suitable remote location with reliable high‑speed internet access. Work is performed in a climate‑controlled environment using standard office equipment including computer, phone, and video conferencing tools. Your standard work schedule and hours will be established in collaboration with your leader and may be adjusted to align with evolving business needs. Acknowledgements The above job description is not intended to be an all‑inclusive list of duties and standards of the position. Incumbents will follow any other instructions, and perform any other related duties, as assigned by their supervisor. Pay Transparency, Budgeted Range

$165,000—$175,000 USD

Science - Minded, Patient - Focused. At GeneDx, we create, follow, and are informed by cutting‑edge science. With over 20 years of expertise in diagnosing rare disorders and diseases, and pioneering work in the identification of new disease‑causing genes, our commitment to genetic disease detection, discovery, and diagnosis is based on sound science and is focused on enhancing patient care. Experts In What Matters Most. With hundreds of genetic counselors, MD/PhD scientists, and clinical and molecular genomics specialists on staff, we are the industry’s genetic testing experts and proud of it. We share the same goal as healthcare providers, patients, and families: to provide clear, accurate, and meaningful answers we all can trust. SEQUENCING HAS THE POWER TO SOLVE DIAGNOSTIC CHALLENGES. From sequencing to reporting and beyond, our technical and clinical experts are providing guidance every step of the way:

TECHNICAL EXPERTISE

High‑quality testing: Our laboratory is CLIA certified and CAP accredited and most of our tests are also New York State approved. Advanced detection: By interrogating genes for complex variants, we can identify the underlying causes of conditions that may otherwise be missed.

CLINICAL EXPERTISE

Thorough analysis: We classify variants according to our custom adaptation of the most recent guidelines. We then leverage our rich internal database for additional interpretation evidence. Customized care: Our experts review all test results and write reports in a clear, concise, and personalized way. We also include information for research studies in specific clinical situations. Impactful discovery: Our researchers continue working to find answers even after testing is complete. Through both internal research efforts and global collaborations, we have identified and published hundreds of new disease‑gene relationships and developed novel tools for genomic data analysis. These efforts ultimately deliver more diagnostic findings to individuals. Learn more About Us here. Our Culture At GeneDx, we are dedicated to cultivating an environment where creativity and innovation thrive. We believe in the power of community and collaboration, where diverse perspectives are embraced, and every voice contributes to our shared success. Our team is a vibrant mix of professionals who challenge and support each other in equal measure, fostering growth both personally and professionally. When you join us, you're not just taking on a job—you're joining a movement. A movement that champions curiosity, embraces change, and believes in making an impact, one patient at a time. Cultural principles we live by: Be bold in our vision & brave in our execution. Communicate directly, with empathy. Do what we say we're going to do. Be adaptable to change. Operate with a bias for action. Benefits include: Paid Time Off (PTO) Health, Dental, Vision and Life insurance 401k Retirement Savings Plan Employee Discounts Voluntary benefits GeneDx is an Equal Opportunity Employer. All privacy policy information can be found here. #J-18808-Ljbffr GeneDx