Sign up to access all features of our service.
  • Job search
  • Favorites
  • Create a CV
    New
  • Salaries
  • Subscriptions

Principal Scientist (M.D. or D.O.)

Exponent

Principal Scientist

Exponent is the only premium engineering and scientific consulting firm with the depth and breadth of expertise to solve our clients' most profoundly unique, unprecedented, and urgent challenges.

We are seeking a medical doctor and experienced consultant for the position of Principal Scientist in our Health Sciences Practice. This position is open across all U.S. office locations. In this role, you will collaborate with multidisciplinary teams to provide strategic leadership and expert guidance on projects involving medical evaluations, causation analysis, risk assessment, and risk communication. These projects span a broad spectrum of products, medical devices, therapies and various health endpoints and medical conditions. Projects may also include the evaluation of mechanism of action; dose response; health hazard indices; review of medical, scientific and epidemiologic literature; comparative risk research; analyses using data science tools; and/or assistance with regulatory documents and analyses. Review and interpretation of medical records, physician notes, dosing and recommended use, and other factors will also be undertaken in these projects, as will review of relevant epidemiologic and medical sources for causation analyses. You will lead complex projects, cultivate relationships with existing clients, identify new business opportunities, and contribute to the growth of our Health Sciences Practice.

You will be responsible for:

  • Leveraging deep knowledge in medicine to address a wide range of complex human health challenges across diverse client sectors, therapies, clinical health endpoints, and patients, delivering scientifically rigorous and impactful solutions.
  • Identifying, pursuing, and securing new client engagements by understanding emerging needs and building long-term partnerships.
  • Maintaining and growing trusted relationships with existing clients by consistently delivering high-quality work, anticipating future needs, and serving as a strategic advisor.
  • Building, managing, and empowering multidisciplinary teams, fostering a collaborative and inclusive environment that values diverse perspectives and scientific integrity.
  • Providing guidance, coaching, and professional development opportunities to technical staff, supporting their growth into future leaders and experts.
  • Ensuring successful project execution through effective planning, resource allocation, and budget management, while maintaining high standards of quality and timeliness.
  • Offer high-level scientific and strategic advice to both internal stakeholders and external clients, contributing to the firm's thought leadership and client impact.
  • Enhancing the firm's visibility and credibility by publishing in peer-reviewed journals, presenting at industry conferences, leading seminars, and participating in expert advisory or technical committees.

You will have the following skills and qualifications:

  • Doctor of Medicine (M.D.), Doctor of Osteopathic Medicine (O.D.), or equivalent degree from an accredited medical school.
  • Ph.D. or M.S. degree in Epidemiology or a related scientific discipline is preferred.
  • Minimum of 8 years of consulting experience in the pharmaceutical or public health areas.
  • Past or current clinical experience preferred.
  • Proven track record of business generation and attracting new and repeat clients or funding.
  • Expertise in epidemiologic study design and real-world evidence generation (e.g., non-interventional, database studies, registries).
  • Knowledge in regulatory science, pharmacovigilance, clinical development, or HEOR.
  • Critical appraisal and scientific interpretation of observational studies.
  • Experience managing or contributing to multidisciplinary project teams and mentoring staff.
  • Exceptional verbal and written communication skills, with the ability to articulate complex ideas clearly and persuasively to diverse audiences.
  • Strong analytical and problem-solving skills, with the ability to interpret data, identify trends, and make informed recommendations in your scientific field.
  • Outstanding reputation among clients and the scientific community for integrity, responsiveness, and technical expertise.
  • Strong commitment to professional development.

Applicants are encouraged to submit a CV (Curriculum Vitae) with publications (feel free to include publications that are in review or pending) [not restricted to 1 page].

Exponent
Vacancy posted 21 hours ago
Similar jobs that could be interesting for youBased on the Principal Scientist (M.D. or D.O.) in Chicago, IL vacancy
  • Fresenius SE & Co. KGaA is looking for a leader for the Extractables & Leachables (E&L) team in Melrose Park, Illinois. You will manage study execution, ensuring compliance with regulatory standards while generating high-quality data to support product submissions. Your...
    Principal

    Fresenius SE & Co. KGaA

    Melrose Park, IL
    3 days ago
  • $85k - $160k

     ...LVI Associates is seeking a Principal Natural Resources Scientist in Rolling Meadows, IL. This position involves providing technical leadership for natural resources investigations and environmental permitting, blending scientific expertise with client oversight. Candidates... 
    Principal

    LVI Associates

    Chicago, IL
    3 days ago
  •  ...As a Senior Fermentation Scientist, you will be the technical cornerstone of our bioprocess development team. This role is designed for a data-driven expert who thrives at the intersection of metabolic physiology and industrial scale-up. You will lead the design, optimization... 
    Principal

    Nature's Fynd

    Chicago, IL
    3 days ago
  • $85k - $160k

     ...opportunities for senior professionals to take meaningful ownership of projects and client relationships. Job Title Principal Natural Resources Scientist Location Rolling Meadows, IL (In‑office with flexibility based on project and team needs) Role Summary... 
    Principal
    Work at office
    Local area

    LVI Associates

    Chicago, IL
    3 days ago
  • $80k - $95k

    Job Summary Provide leadership and direction to the Extractables & Leachables (E&L) team, managing study execution and associated processes to ensure efficient and compliant program delivery. Oversee the full lifecycle of E&L activities, including study design, protocol...
    Principal
    Work experience placement
    Flexible hours

    301044 Fresenius Kabi USA, LLC

    Melrose Park, IL
    3 days ago
  • $224k - $336k

     ...systems that are safe, reliable, and impactful in production. Job Description and Requirements ABOUT THE ROLE As a Principal Applied Scientist, Reliability, you will lead the design and validation of intelligent systems that customers can trust in highstakes legal... 
    Principal
    Remote work

    Relativity

    Chicago, IL
    2 days ago
  • A leading food development company in Chicago is seeking a Senior Research and Development Scientist to lead the development and commercialization of bakery products. This role encompasses cookies, bars, and gluten-free products, involving collaboration across functions... 
    Principal

    CPS Inc.

    Chicago, IL
    2 days ago
  • $225k - $275k

     ...Principal Scientist ID 2025-2214 Location US-CA-Menlo Park Practice Polymers and Chemistry Position Type Full-time Posted Salary Range USD $225,000.00 - USD $275,000.00 /Yr. About Exponent Exponent is the only... 
    Principal
    Full time
    Work at office
    Flexible hours

    Exponent

    Chicago, IL
    21 hours ago
  •  ...te estamos buscando a ti! Mr. Appliance está buscando un técnico principal de reparación de electrodomésticos. ¡Aplica hoy!Si valoras...  ...puesto de Técnico de Electrodomésticos.Diploma de escuela secundaria o su equivalenteLicencia de conducir válida y registro de manejo limpio... 
    Principal

    Hunter Super Techs - TurnPoint

    Chicago, IL
    4 days ago
  • $19 - $23 per hour

     ...personales Colabora con otros profesionales del cuidado infantil y sigue creciendo en tu profesión Cualificaciones Se prefiere un Asociado o Grado en Artes en Educación Infantil o campo relacionado Asociado de Desarrollo Infantil (CDA) preferido Se requieren 2 años de... 
    Principal

    The Goddard School of Chicago (West Loop), IL

    Chicago, IL
    21 hours ago
  • $19 - $25 per hour

    Profesor principal de preescolar - 19-25 $/hora (según la experiencia) - Sin fines de semana - Descuento en cuidado infantil Toddler Town...  ...infantil Se prefiere experiencia como profesora de preescolar o guardería Conocimiento de los estándares y requisitos de la Asociaci... 
    Principal
    Monday to Friday

    Toddler Town Children’s Learning Academy

    Evanston, IL
    4 days ago
  • $137.4k - $240.4k

     ...using technology and exceptional service. Job Description The Sr Principal, SDLC Testing Governance is a senior individual contributor and...  ...this opportunity (no sponsorship is available for H‑1B, L‑1, TN, O‑1, E‑3, H‑1B1, F‑1, J‑1, OPT, CPT or any other employment‑based... 
    Principal
    H1b

    001 The Northern Trust Company

    Chicago, IL
    4 days ago
  • A leading technology company is seeking a Principle Researcher in Workforce Intelligence, focusing on Machine Learning to drive strategic research initiatives. This role requires 10+ years of experience in data science, with advanced proficiency in Python, R, SQL, and ML...
    Principal

    salesforce.com, inc.

    Chicago, IL
    21 hours ago
  • $125k - $175k

     ...Job Description Sr. Claim Manager - D&O/EPL Seeking a highly skilled and experienced Senior Claim Manager/Attorney specializing in Executive Liability, Directors & Officers (D&O), and Employment Practices Liability (EPL) claims. This hybrid role provides an... 

    The Jonus Group

    Chicago, IL
    2 days ago
  • $75k

    A prestigious research university in Chicago is seeking a Principal Researcher to support collaborative research with faculty. The role demands a PhD in a relevant field and proficiency in Python for statistical analysis. Responsibilities include conducting data collection... 
    Principal
    Full time
    Work at office

    The University Of Chicago

    Chicago, IL
    4 days ago
  • $97k - $189k

     ...industry. The role requires exceptional communication skills, the ability to negotiate complex settlements, and expertise in Public D&O and Financial Institutions E&O claims. This position offers a competitive salary range of $97,000 to $189,000 based on experience. #J... 

    01460 Continental Casualty Company

    Chicago, IL
    2 days ago
  • $115k - $140k

    A leading insurance provider is seeking an experienced E&O Senior Underwriter based in Chicago or NYC. Responsibilities include underwriting a complex portfolio, maintaining broker relationships, and mentoring junior staff. Candidates should have a minimum of 6 years in... 

    Vault Risk Management Services, LLC

    Chicago, IL
    1 day ago
  • $140k - $170k

     ...per year, along with comprehensive benefits including medical and 401(k) plan. The ideal candidate has extensive experience in D365 F&O and managing application lifecycle management, and must live within commuting distance to Chicago. #J-18808-Ljbffr 1026 Avanade Inc.... 

    1026 Avanade Inc. Company

    Chicago, IL
    2 days ago
  •  ...specialty insurance provider in Chicago is seeking a Claims Manager with 6 to 10 years of experience to manage complex claims including D&O, E&O, and EPL. The ideal candidate will have a Juris Doctor and demonstrate excellent communication and analytical skills.... 

    Westfield Specialty

    Chicago, IL
    21 hours ago
  • $62k - $70k

     ...Job Description Job Description Position: Environmental Social Scientist, Chicago Region FLSA Status: Exempt Department: Keller Science Action Center Our Mission: Since the 1893 World Columbian Exposition, our organization has aimed to connect people... 
    Local area
    Shift work

    Field Museum

    Chicago, IL
    24 days ago
  • $118.9k - $174.4k

    A reputable insurance company is seeking an Underwriter/Senior Underwriter for Lawyers Professional Liability and E&O lines. The position offers a hybrid work environment in Chicago, IL, and supports professional growth with a path to leadership. Responsibilities include... 
    Flexible hours

    Cfins

    Chicago, IL
    1 day ago
  •  ...looking for a D365 Senior Supply Chain & Manufacturing Functional Consultant in Chicago, IL. You will be instrumental in leading the D365 F&O Manufacturing workstream, analyzing requirements, and transforming business demands into operational solutions. The ideal candidate... 

    Avanade Spain SL

    Chicago, IL
    21 hours ago
  • $155k - $190k

    Principal Researcher in Child Welfare will lead business pursuits related to federal, state, and local child welfare policy and program research and evaluation. We seek a dynamic business development leader contributing to the expansion and management of a robust portfolio... 
    Principal
    Full time
    Contract work
    Work experience placement
    H1b
    Work at office
    Local area
    Remote work

    American Institutes for Research

    Chicago, IL
    2 days ago
  •  ...internal meetings In order to be successful in this role, we need someone who has: · Current active ServiceNow certifications: o Certified System Administrator (CSA) o Certified Implementation Specialist in Risk and Compliance (CIS-RC) · 10-12 years of... 
    Principal
    Work at office
    Remote work
    Flexible hours

    ServiceNow

    Chicago, IL
    2 days ago
  • $75k

     ...achieve this accomplishment. For more information about the University of Chicago Booth School of Business, please visit: Summary**The Principal Researcher provides a supportive research environment to a highly qualified recent PhD. The Principal Researcher collaborates with... 
    Principal
    Work experience placement
    Work at office
    3 days per week

    The University Of Chicago

    Chicago, IL
    4 days ago
  • $187.5k - $240k

    I did my part and supported the Regular Toilet is seeking a Principal User Researcher to enhance product strategy through user insights and research. In this role, you will champion user needs and drive cross-functional collaborations to ensure user-centric product design... 
    Principal

    I did my part and supported the Regular Toilet

    Chicago, IL
    1 day ago
  • $100k - $143.01k

     ...underwriting company in Chicago is seeking a professional with over 5 years of experience handling professional liability claims, including E&O and Cyber. Responsibilities include assessing coverage issues, conducting investigations, and managing claims effectively. The... 
    Flexible hours

    RLI Corp

    Chicago, IL
    4 days ago
  • $112.13k - $186.88k

     ...Turnitin, LLC is looking for a Senior Machine Learning Scientist to perform research, model training, and dataset construction. The role is remote-based within the USA, requiring expertise in machine learning and software engineering. Candidates should have at least... 
    Remote work

    Turnitin

    Chicago, IL
    3 days ago
  • ServiceNow, Inc. in Chicago is looking for a Technical Consultant to join their Expert Services team. This role involves consulting with customers and configuring ServiceNow's Risk & Resilience products. The ideal candidate will have over 10 years of ServiceNow experience...
    Principal
    Remote work

    ServiceNow

    Chicago, IL
    3 days ago
  • $150k

    Bowhead Specialty is seeking an experienced Complex Underwriting Manager to join our Private Commercial D&O team. This role, with national underwriting responsibilities, focuses on large, complex risks and private equity-backed companies. Responsibilities include underwriting... 

    Bowhead Specialty

    Chicago, IL
    1 day ago

Do you want to receive more vacancies?

Subscribe and receive similar vacancies to Principal Scientist (M.D. or D.O.). Be the first to apply!