Research Investigator - Transgenic Mouse Models

Overview The Translational Molecular Pathology department at MD Anderson Cancer Center is dedicated to advancing cancer research by bridging laboratory discoveries with clinical application. This team focuses on developing innovative models and methodologies that drive a deeper understanding of cancer biology and support the development of targeted therapies. As a Senior Research Assistant, you will play a key role in preclinical research with a strong emphasis on transgenic mouse models , contributing directly to studies that inform future clinical advancements. This position is ideal for someone with hands‑on experience in animal models who is comfortable working independently while supporting a collaborative research environment. In this role, you will design and execute animal experiments , including generating and maintaining transgenic mouse models, performing carcinogen and drug studies, and harvesting tissues for downstream analysis. You will apply a variety of molecular and immunological techniques , including flow cytometry, qPCR, western blotting, and cell culture, to support ongoing research projects. You will work closely with leadership to define project goals and translate them into structured experimental plans, developing step‑by‑step procedures to ensure accuracy, reproducibility, and alignment with study objectives. Your ability to independently manage multiple projects simultaneously while maintaining attention to detail will be critical to success. Collaboration is an important component of this role, as you will also support other lab members with experiments involving transgenic models and contribute to overall laboratory productivity. At the same time, you will be expected to take ownership of your work, demonstrating initiative and strong problem‑solving skills in a fast‑paced research setting. This position offers the opportunity to work on cutting‑edge translational research , directly supporting efforts to better understand cancer and improve patient outcomes through innovative preclinical studies. Key Responsibilities Perform independent animal experiments, including carcinogen and drug injections, collection of samples and tissues from mice, and generation of animal models. Execute assays such as flow cytometry, QPCR, western blotting, and cell culture. Discuss project goals with supervisor and, with guidance, develop a step‑by‑step written procedure outlining the experiment. Manage several research projects concurrently in an independent manner. Perform additional duties as assigned. Qualifications Bachelor's degree in one of the natural sciences or a related field. Five years of experience in scientific or experimental research work. (With a preferred degree, three years of required experience.) This position may be responsible for maintaining the security and integrity of critical infrastructure, as defined in Section 113.001(2) of the Texas Business and Commerce Code, and therefore may require routine reviews and screening. The ability to satisfy and maintain all requirements necessary to ensure the continued security and integrity of such infrastructure is a condition of hire and continued employment. Benefits MD Anderson offers a comprehensive total rewards package, including paid medical benefits, generous paid time off, retirement plans, and additional benefits, along with opportunities for professional growth within a world‑renowned research institution. MD Anderson offers excellent benefits, including medical, dental, paid time off, retirement, tuition benefits, educational opportunities, and individual and team recognition. EEO Statement The University of Texas MD Anderson Cancer Center is an equal opportunity employer. It provides equal employment opportunity without regard to race, color, religion, age, national origin, sex, gender, sexual orientation, gender identity/expression, disability, protected veteran status, genetic information, or any other basis protected by institutional policy or by federal, state or local laws unless such distinction is required by law. Legal Statements Additional Information Requisition ID: 182122 Employment Status: Full‑Time Employee Status: Regular Work Week: Days Minimum Salary: US Dollar (USD) 59,000 Midpoint Salary: US Dollar (USD) 74,000 Maximum Salary: US Dollar (USD) 89,000 FLSA: exempt and not eligible for overtime pay Fund Type: Soft Work Location: Onsite Pivotal Position: Yes Referral Bonus Available?: Yes Relocation Assistance Available?: Yes #J-18808-Ljbffr University of Texas MD Anderson Cancer Center