Executive Director, Global Program Lead, Oncology (Pumitamig)

Working with Us

Challenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You'll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible.

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Position Summary

BMS is hiring an Executive Director, Global Program Leader, Pumitamig. This individual will report to the Vice President, GPL Pumitamig, and will be responsible for leading a portion of the Pumitamig development book of work. Pumitamig is a PD-L1xVEGFF bispecific antibody being developed in a range of solid tumors in collaboration with our external partner BioNTech.

Global Program Leads within the HOCT (Hematology, Oncology & Cell Therapy) Global Program Leadership organization are strategic-thinking, problem-solving, and action oriented scientific leaders who bring drug development and commercialization insights to drive a sustainable pipeline of innovative medicines. GPLs serve as the point of accountability for their assets and are respected, matrix leaders, overseeing multi-disciplinary teams. They foster a high performing, highly collaborative, truth-seeking team environment aimed at developing and implementing compelling, integrated asset strategies to achieve ambitious near- and long-term portfolio objectives. Each leader is accountable to therapeutic area, R&D, commercial and Company Leadership for: (i) creating a vision and defining the strategy and integrated development plan for each asset within their portfolio, (ii) developing a set of objective criteria against which each asset advancing through the pipeline will be evaluated to enable robust debate and rapid, data-driven decision making; and (iii) ensuring that only high quality and differentiated assets enter the market.Key Responsibilities

Strategy and Execution

• Uses an understanding of disease biology, the drug development process (particularly cross-functional connectivity), and relevant late-stage challenges (e.g., trends in disease area therapeutic advances, and evolving regulatory, patient advocacy and market access environments) to create a vision for each asset, then design and execute effective development programs in support of the overall R&D portfolio goals.

• Effectively engages cross company expertise and utilizes advisory groups and governance bodies to define, revise and champion asset development strategies and implementation plans.

• Continually analyzes progress, engages in critical thinking, and asserts strong problem-solving toward delivering key data and interpretation essential for robust debate and rapid, data-driven decision making on assigned projects.

• Delivers high quality assets to commercial which have the potential for a competitive profile to address the unmet medical needs of patients and to provide favorable shareholder return.

• Ensures the process and output of the team meets established program standards (per PD&C Process expectations, within budget, on schedule, compliant, etc.), while also looking for opportunities to streamline development and enable continuous improvements without compromising quality.

• Engages senior leaders and functional area stakeholders to ensure alignment of program strategy and operational plans with functional area capabilities, and clearly communicates program risks, implications of changes in the competitive landscape and progress toward key milestones.

• Actively provides input to and drives portfolio level strategy for both internal and external opportunities.

• Participates in regulatory filings (NDA, BLA filings) as well as develops strategy for orphan drug designation.

• Engages with Health Authorities and/or Advisory Committees in the design of clinical trials and endpoints.

• Leads team to develop program strategy and clinical program, commercialization strategy plans, business case development, and understands how access, pricing and reimbursement needs for supporting value proposition will inform trial design.

• Builds and maintains collaborative relationships with external stakeholders (Opinion Leaders, Strategic Alliance Partners, Patient Advocacy Leaders, Health Authorities) and appropriately incorporates insights and advice to maximize program impact.

• Understands clinical trial operational complexities from study start up through enrollment, quality assurance, and study readout.

• Has an active role in analysis and/or interpretation of clinical data and translation into scientific communication strategy, including publications, and commercial strategy.

• Understands and reflects the impact of VAP inputs (Early Access Review and DEX recommendations, commercial opportunity assessment, TOP / TPP requirements, and value drivers as inputs in clinical trial design.

• Actively supports Investor Relations and Public Affairs in managing external BMS communications.

• Integrates commercialization inputs and deliverables to design the late program strategy that enables approval of a meaningfully differentiated asset with potential to maximize asset value.

• Understands necessary commercial inputs needed to inform the end-to-end development process leading to regulatory approval and successful commercialization.

• Integrates market inputs (e.g., TPP, DEX/VAP, CI insights) into the integrated development plan, including clinical plans and labeling strategy; Appreciates translation of clinical data into claims and considerations for label development.

• Understands and contributes to development of forecasts and investment scenarios, how to assess risk and conduct valuations, and implications for decision-making.

• Contributes to the development of brand hallmarks and brand strategy (generic name, brand name, logo, brand colors, positioning, messaging, campaign, segmentation, promotional strategy) understanding the relationship to clinical trial design.

• In partnership with Medical Affairs, supports development of KOL plans and engagements, and leverages KOL input in context of development programs and communicating evidence.

• Supports commercial needs and recommendations to guide CMC and GPS on trade packaging and commercial product.

Leadership and Matrix Alignment

• Inclusively Collaborates Across the BMS Matrix with an Enterprise Mindset: Effectively collaborates with matrix functions by building trust and driving toward the collective success of the program

• Demonstrates Enterprise Mindset Problem-Solving and Decision Making: Gathers diverse perspectives assess alternate resolutions and makes thoughtful, informed Enterprise decisions

• Develops and Leads a High Performing Matrix Team: Builds, leads and inspires high performing cross functional matrix team through a unified program strategy on behalf of our patients

• Holds Oneself and Others Accountable: Takes initiative to address challenges, removes barriers, holds others accountable for the collective success of the program outcomes and team collaboration

• Demonstrates Character: Leads with integrity & the values of self-awareness & humility and seeks feedback

Qualifications & Experience

• MD, PhD, DVM, PharmD, MBA or equivalent advanced degree of relevance, with experience in the drug development process.

• 10+ years of experience in the drug development process and leadership experience in academic or industry setting, including education where applicable.

• Expertise in the drug development process with in-depth know-how and experience in matrix team leadership, relevant regulatory expectations, and overall drug development and commercialization.

• Successful track record of leading through influence and working across complex, global organizational matrix.

• Significant experience in oncology, specifically lung preferred, with demonstrated understanding of the role of basic biology, pharmaceutical optimization, translational medicine, and clinical pharmacology, including exposure-response relationships and dose selection.

• Strong understanding of relevant regulatory health authority expectations and regulations for drug development and impact on commercialization.

• Working knowledge of all functional areas of exploratory development, including chemistry/biochemistry, biology, toxicology, CMC, translational medicine, early clinical development, etc.

• Demonstrated scientific acumen and mechanistic understanding of pharmacology and disease biology.

• Ability to create a clear purpose, global vision, strategies and key priorities for competing successfully in the evolving pharmaceutical and health care industry.

• Demonstrated ability to lead cross-functional team to execute Development Plans which have global perspective and focus on product differentiation, including opportunities for data driven acceleration.

• Demonstrated ability to objectively assess complex but relatively sparse data sets, make informed decisions and take action in the face of uncertainty.

• Demonstrated ability to present complex programs to senior leaders and influence decision making.

• Experience in successfully managing and leading high performing, cross-functional matrix teams or complex multi-functional organizations.

• Demonstrated ability to coach and mentor others to enhance performance and/or facilitate career progression.

• Ability to effectively and seamlessly multi-task, and prioritize across multiple development assets, with complex strategies and accelerated development timelines.

• Demonstrated ability to successfully and effectively cooperate, collaborate and work across functions.

• Demonstrated ability to advise and participate in business development due-diligence evaluations and transaction recommendations.

If you come across a role that intrigues you but doesn't perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.

Compensation Overview:

$297,590 - $360,603

The starting compensation range(s) for this role are listed above for a full-time employee (FTE) basis. Additional incentive cash and stock opportunities (based on eligibility) may be available. The starting pay rate takes into account characteristics of the job, such as required skills, where the job is performed, the employee's work schedule, job-related knowledge, and experience. Final, individual compensation will be decided based on demonstrated experience.

Eligibility for specific benefits listed on our careers site may vary based on the job and location. For more on benefits, please visit

Benefit offerings are subject to the terms and conditions of the applicable plans in effect at the time and may require enrollment. Our benefits include:

• Health Coverage: Medical, pharmacy, dental, and vision care.

• Wellbeing Support: Programs such as BMS Well-Being Account, BMS Living Life Better, and Employee Assistance Programs (EAP).

• Financial Well-being and Protection: 401(k) plan, short- and long-term disability, life insurance, accident insurance, supplemental health insurance, business travel protection, personal liability protection, identity theft benefit, legal support, and survivor support.

Work-life benefits include:

Paid Time Off

• US Exempt Employees: flexible time off (unlimited, with manager approval, 11 paid national holidays (not applicable to employees in Phoenix, AZ, Puerto Rico or Rayzebio employees)

• Phoenix, AZ, Puerto Rico and Rayzebio Exempt, Non-Exempt, Hourly Employees: 160 hours annual paid vacation for new hires with manager approval, 11 national holidays, and 3 optional holidays

Based on eligibility*, additional time off for employees may include unlimited paid sick time, up to 2 paid volunteer days per year, summer hours flexibility, leaves of absence for medical, personal, parental, caregiver, bereavement, and military needs and an annual Global Shutdown between Christmas and New Years Day.

All global employees full and part-time who are actively employed at and paid directly by BMS at the end of the calendar year are eligible to take advantage of the Global Shutdown.

* Eligibility Disclosure: T he summer hours program is for United States (U.S.) office-based employees due to the unique nature of their work. Summer hours are generally not available for field sales and manufacturing operations and may also be limited for the capability centers. Employees in remote-by-design or lab-based roles may be eligible for summer hours, depending on the nature of their work, and should discuss eligibility with their manager. Employees covered under a collective bargaining agreement should consult that document to determine if they are eligible. Contractors, leased workers and other service providers are not eligible to participate in the program.

Uniquely Interesting Work, Life-changing Careers

With a single vision as inspiring as Transforming patients' lives through science™ , every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in a supportive culture, promoting global participation in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

On-site Protocol

BMS has an occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:

Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.

Supporting People with Disabilities

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to View email address on click.appcast.io . Visit careers.bms.com/ ( eeo-accessibility to access our complete Equal Employment Opportunity statement.

Candidate Rights

BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information:

Data Protection

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If you believe that the job posting is missing information required by local law or incorrect in any way, please contact BMS at View email address on click.appcast.io . Please provide the Job Title and Requisition number so we can review. Communications related to your application should not be sent to this email and you will not receive a response. Inquiries related to the status of your application should be directed to Chat with Ripley.

R1602386 : Executive Director, Global Program Lead, Oncology (Pumitamig) Company: Bristol-Myers Squibb

Req Number: R1602386

Updated: 2026-05-30 05:39:50.511 UTC

Location: Cambridge-MA

Bristol Myers Squibb is an equal opportunity employer. Qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, protected veteran status, pregnancy, citizenship, marital status, gender expression, genetic information, political affiliation, or any other characteristic protected by law.