Sign up to access all features of our service.
  • Job search
  • Favorites
  • Create a CV
    New
  • Salaries
  • Subscriptions

Enterprise Architect - Pharma Commercial

$170.8k - $317.2k

F. Hoffmann-La Roche AG

Enterprise Architect – Pharma Commercial Opportunity The Enterprise Architect – Pharma Commercial acts as the strategic bridge between the central Strategy, Portfolio & Governance (SPG) organization and Pharma Medicines. Operating within a federated model, you will orchestrate the global Pharma Commercial architecture network, translating business goals into future‑ready technology roadmaps across Market Access, Marketing, Customer Engagement, Analytics, and Commercial Operations. Once hired, the actual title will be Domain Architect – Pharma Commercial. Key Responsibilities Partner with Business and Roche Digital Technology (RDT) leadership to align global and regional business priorities with multi‑year technology roadmaps and target‑state architectures. Lead a federated network of embedded domain and solution architects. Establish shared strategic priorities, technology guardrails, and security/privacy standards. Drive architectural success for high‑impact initiatives, including customer engagement modernization (e.g., Elevate, AI‑driven content supply chains, and patient strategy). Develop and maintain commercial capability maps, target‑state architectures, and technology inventories using tools like ArchiMEDES (SAP LeanIX). Guide investment decisions alongside Portfolio Management by evaluating strategic impacts, maximizing platform reuse, and managing technical debt to optimize total cost of ownership (TCO). Monitor emerging commercial technology trends and evaluate vendors to maintain a future‑ready, optimized architecture. Collaborate with legal, compliance, and cybersecurity teams to ensure all commercial architectures adhere to global data privacy regulations (e.g., GDPR, HIPAA) and patient data governance standards. Who You Are Bachelor’s degree in Engineering, IT, or Science. A Master’s degree is preferred. 10+ years of direct experience in IT and enterprise/domain architecture, with a proven history of migrating legacy commercial systems to modern, cloud‑native ecosystems. 5+ years of experience within the biotech/pharma industry. Proven track record navigating and influencing within a complex, matrixed, or federated global organization. Deep domain expertise in global Pharma Commercial operations (Field CRM, Omnichannel Marketing, Market Access, and Patient Services). Technical Skills Strong expertise in modern digital tech stacks (e.g., Veeva, Salesforce) and high‑volume integrations between front‑ and back‑office systems. Proficiency in architecting scalable data products, MDM (Master Data Management), and AI‑driven commercial data solutions. Highly skilled in designing pragmatic target‑state architectures and evolving roadmaps aligned with complex business needs. Familiarity with enterprise architecture frameworks (e.g., TOGAF) and agile/product‑led delivery methodologies. Leadership & Communication Demonstrated ability to cultivate, inspire, and lead networks of architects via influence rather than authority (no direct reporting lines). Trusted advisor to senior leadership with strong executive presence and business acumen. Excellent at translating complex architectural strategies into relatable, business‑centric narratives that balance enterprise coherence with local agility. Salary The expected salary range for this position based on the primary location of South San Francisco, CA is $170,800 – $317,200. Actual pay will be determined based on experience, qualifications, geographic location, and other job‑related factors permitted by law. A discretionary annual bonus may be available based on individual and company performance. Benefits Relocation benefits are not available for this job posting. EEO Statement Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of protected veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws. If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants. #J-18808-Ljbffr F. Hoffmann-La Roche AG

Vacancy posted 3 days ago
Similar jobs that could be interesting for youBased on the Enterprise Architect - Pharma Commercial in South San Francisco, CA vacancy
  • $170.8k - $317.2k

    Enterprise Architect - Pharma Commercial The Opportunity Enterprise Architect - Pharma Commercial acts as the strategic bridge between the central Strategy, Portfolio & Governance (SPG) organization and Pharma Medicines. Operating within a federated model, you will orchestrate... 
    Commercial
    Local area
    Relocation package

    JobRx, Inc.

    South San Francisco, CA
    4 days ago
  •  ...Summary We are seeking an experienced Enterprise Forecasting Architect to lead the design and...  ...candidate will possess deep expertise in commercial forecasting, data engineering, cloud...  ...Data Product Architect (Commercial Pharma) This role goes beyond traditional data... 
    Commercial

    Silicontek Inc

    South San Francisco, CA
    2 days ago
  • $189.3k - $351.5k

     ...Development organisations at Genentech (gRED) and Pharma (pRED) have demonstrated how these...  ...The Research & Early Development Architect is a strategic technology and organizational...  ...you will help shape and drive a modern enterprise architecture vision across Research & Early... 
    Suggested
    Work experience placement
    Local area
    Immediate start
    Worldwide
    Relocation package
    3 days per week

    F. Hoffmann-La Roche AG

    South San Francisco, CA
    2 days ago
  •  ...we are establishing a modern enterprise data foundation powered by Databricks...  ..., supply chain, finance and commercial systems. We are seeking a Principal Enterprise Data Architect, a highly hands-on individual...  ...academics, biotechs, and pharma companies to accelerate drug... 
    Commercial
    Flexible hours

    Cellares

    South San Francisco, CA
    8 days ago
  •  ...Senior Sales Executive- Strategic Solutions to drive growth within enterprise accounts and shape global payments capabilities from San...  ...accelerate revenue. This is a high-visibility role with cross-functional collaboration across product and commercial #J-18808-Ljbffr Worldpay
    Commercial

    Worldpay

    San Francisco, CA
    2 days ago
  • $205k - $235k

     ...Parthenon – Strategy & Execution – Deal Technology Health – Enterprise Architect - Director The opportunity EY-Parthenon’s unique...  ...analytics) to deliver measurable business impact. A strong commercial mindset and the ability to balance efficiency with innovation... 
    Commercial
    Work experience placement
    Summer holiday
    Work at office
    Flexible hours

    EY

    San Francisco, CA
    2 days ago
  • $250k - $290k

     ...Parthenon - Strategy & Execution - Deal Technology - Health - Enterprise Architect - Senior Director Location: Atlanta, Boston, Chicago,...  ...analytics) to deliver measurable business impact. A strong commercial mindset and the ability to balance efficiency with innovation... 
    Commercial
    Work experience placement
    Summer holiday
    Work at office
    Flexible hours

    EY-Parthenon

    San Francisco, CA
    2 days ago
  • $200.1k - $371.5k

     ...Opportunity As the Head of Product Engineering for Commercial Pharma Data Architecture/Management, you are the visionary architect of the data engine powering our global...  ...with absolute consistency across the enterprise. Insights-to-Action: Partner with Analytics... 
    Commercial
    Local area
    Relocation package

    Genentech

    South San Francisco, CA
    5 days ago
  • $200.1k - $371.5k

    A leading healthcare firm in South San Francisco is seeking a Head of Product Engineering for Commercial Pharma Data Architecture/Management. You will architect data solutions that drive business success across the Pharma sector. Ideal candidates will bring 15+ years in... 
    Commercial

    Genentech

    South San Francisco, CA
    5 days ago
  •  ...Business Partner to bridge US market needs with Global Supply Chain, ensuring continuous product availability. You will balance commercial plans with manufacturing capacity and lead cross‑functional teams through supply constraints. You will influence leadership with... 
    Commercial

    Genentech

    South San Francisco, CA
    3 days ago
  • Planet Pharma Group is seeking a Director / Associate Director, New Product Planning - Early Pipeline in South San Francisco. This strategic role involves leading commercial assessments and insights for early pipeline assets, ensuring alignment between scientific innovation... 
    Commercial

    Planet Pharma Group

    South San Francisco, CA
    3 days ago
  • Genentech in South San Francisco, CA seeks an Enterprise Architect - Pharma Commercial to bridge Strategy, Portfolio & Governance with Pharma Medicines, shaping a future‑ready technology roadmap for Market Access, Marketing, Customer Engagement, Analytics and Commercial... 
    Commercial

    F. Hoffmann-La Roche AG

    South San Francisco, CA
    3 days ago
  • Genentech is seeking an Enterprise Architect - Pharma Commercial to bridge Strategy, Portfolio & Governance with Pharma Medicines. You will orchestrate a global architecture network across Market Access, Marketing, Customer Engagement, Analytics, and Commercial Operations... 
    Commercial

    Genentech

    South San Francisco, CA
    3 days ago
  • $345k - $425k

     ...development strategy. Lead cross-functional alignment (Regulatory, Commercial, Legal, Clinical). Build relationships with KOLs, investigators...  ...disease. 12+ years combined experience; at least 7 years in pharma/biotech senior medical/clinical roles. 3+ years people‑... 
    Commercial

    Scorpion Therapeutics

    South San Francisco, CA
    2 days ago
  •  ...Francisco. The ideal candidate will have over 10 years of experience in Data Engineering and be proficient in AWS, PySpark, and Pharma Commercial data. The role requires strong leadership in cross-functional teams and involves responsibilities in data modeling, quality,... 
    Commercial

    Saama Technologies Inc

    South San Francisco, CA
    1 day ago
  • $128.9k - $239.5k

    This role is a vital part of the Pharma Technical Operations Supply Chain US team, which connects patient needs to our global network...  ...team, you will serve as a key strategic bridge between the US commercial market and Global Supply Chain operations. You will have the opportunity... 
    Commercial
    Local area
    Relocation package
    Shift work

    F. Hoffmann-La Roche AG

    South San Francisco, CA
    3 days ago
  •  ...collaborate and work with other departments such as Clinical, Commercial, Finance, Research & Development, Manufacturing, and Supply Chain...  ...and/or corporate experience, preferably in a biotech or pharma company. Experience with reviewing confidentiality agreements... 
    Commercial
    Contract work
    Flexible hours

    ACL Digital

    South San Francisco, CA
    1 day ago
  • $156.8k - $291.2k

     ...Position The Opportunity The Finance Enterprise Partner - Therapeutic Area (FEP - TA)...  ...integrating insights from Customer Engagement, commercial, medical affairs, market access, pricing...  .... ~ Strong understanding of pharma revenue mechanics (pricing, access, gross... 
    Commercial
    Temporary work
    Local area
    Relocation package
    Flexible hours

    Genentech

    South San Francisco, CA
    5 days ago
  •  ...South San Francisco, CA is seeking a Senior Program Director, Commercial Regulatory Affairs . Commercial Regulatory Affairs (CORA) is part...  ..., patients, purchasers and prescribers for the client’s global Pharma Division, which includes all therapeutic areas and all phases... 
    Commercial
    Work experience placement
    Remote work
    Worldwide

    Techlifecolumbus

    South San Francisco, CA
    1 day ago
  • $20 - $50 per hour

     ...scale. Partnering with Cellares enables academics, biotechs, and pharma companies to accelerate drug development and scale out...  ...company is headquartered in South San Francisco, California with its commercial-scale IDMO Smart Factory in Bridgewater, New Jersey. The company... 
    Commercial
    Flexible hours
    Night shift

    Cellares

    South San Francisco, CA
    1 day ago
  • $120.8k - $224.3k

     ...Scientist is available in the Analytical Development Department of Pharma Technical Development. The selected candidate will serve as the...  ...expertise. Knowledgeable about CMC development from Phase I to commercial stages. Self‑motivated with excellent organization, oral and... 
    Commercial
    Local area
    Relocation package

    F. Hoffmann-La Roche AG

    South San Francisco, CA
    2 days ago
  • $169.27k - $195.83k

     ...Job Details Job Location: Daly City, CA 94014 Salary Range: $169,265.20 - $195,832.00 The Enterprise Architect will serve as a senior technical architecture leader for NEMS, responsible for defining and governing the enterprise architecture across applications, data,... 
    Full time

    North East Medical Services

    Daly City, CA
    4 days ago
  • $230k - $280k

    BridgeBio Pharma in San Francisco is seeking a Director/Senior Director of Commercial Analytics & Insights to shape and execute a comprehensive analytics strategy for in-line rare disease therapeutics. The successful candidate will lead a team of insights professionals... 
    Commercial

    BridgeBio Pharma

    San Francisco, CA
    2 days ago
  •  ...Analytical Development & Quality Control (ADQC) for US Biologics within Pharma Technical Development (PTD). The role leads a team of ~20,...  ...and control strategy for biologics from preclinical to commercial. Key Responsibilities Lead, coach, mentor and develop a team of... 
    Commercial
    Local area
    Relocation
    Relocation package

    F. Hoffmann-La Roche AG

    South San Francisco, CA
    2 days ago
  • $54 per hour

     ...congestion, and gives people time back. With more than 140 million commercial autonomous miles safely flown, Zipline is redefining access to...  ...can do the impossible at record breaking speeds. About the Enterprise Systems Team We're building the systems that power Zipline... 
    Commercial
    Hourly pay
    Full time
    Internship
    Work at office
    Local area
    Immediate start
    Relocation package

    Zipline

    South San Francisco, CA
    8 days ago
  • $90k - $210k

     ..., preferably within cell and gene therapy Experience in the Pharma/Biotech industry in technology transfer Must know and follow...  ...company is headquartered in South San Francisco, California with its commercial-scale IDMO Smart Factory in Bridgewater, New Jersey. The... 
    Commercial
    Flexible hours

    Cellares

    South San Francisco, CA
    3 days ago
  • Stripe is looking for a Head of Enterprise Solutions Architecture Platforms in South San Francisco. This role involves leading a world-class pre-sales engineering team and collaborating with sales and product teams to develop strategies that drive user engagement and growth... 

    Stripe

    South San Francisco, CA
    4 days ago
  • A leading tech firm is seeking an Enterprise and Commercial Sales Account Manager to develop and drive revenue in the cyber-security space by managing client relationships and closing opportunities. The ideal candidate will have over 5 years of sales experience, particularly... 
    Commercial

    Vaultize

    San Francisco, CA
    3 days ago
  • Role - Data Engineering Tech Lead Mandatory Skills: Pharma Commercial and Digital Marketing data, PySpark, AWS Qualification & Skills Required 10+ years of experience in Data Engineering, Integrations, Data Modeling, Data Profiling, Data Quality, Orchestration Hands on... 
    Commercial
    Work at office
    Local area

    Saama Technologies Inc

    South San Francisco, CA
    1 day ago
  •  ...relationships across engineering platforms, infrastructure software, security technology, enterprise systems, IT, and hardware. Our work connects technical roadmaps, commercial strategy, supplier leverage, financial discipline, operational resilience, and security. About... 
    Commercial
    Work at office
    Relocation package
    Flexible hours

    The Consulting Solutions

    San Francisco, CA
    4 days ago

Do you want to receive more vacancies?

Subscribe and receive similar vacancies to Enterprise Architect - Pharma Commercial. Be the first to apply!