Financial Planning & Analysis Senior Manager

Job Description General Summary: The Senior Manager, FP&A is a key member of Vertex’s Finance Business Partnering organization, providing financial leadership and strategic support to the U.S. Kidney team. As Vertex advances toward commercialization of its Kidney portfolio, this role will help shape and deliver near-term and long-term financial goals. This position will play a critical role in supporting pre-launch and post-launch resource allocation in the U.S., a priority market for the Kidney portfolio. The Senior Manager will partner across Finance, Marketing, Sales, Patient Support, Market Access, and other supporting functions to deliver actionable insights, inform decision-making, and help define the key performance indicators that support business performance and patient access. This role will help drive our annual budget process and will partner closely with functional teams to drive the financial performance management process for responsible functions (objective setting, budget vs. actuals, etc.), including the monthly forecast process, with a focus on influencing business operations and decisions through an understanding of the key drivers of short term performance and communicating the range of possible outcomes. Key Duties and Responsibilities: Provide financial leadership and strategic guidance to functional leaders supporting the U.S. Kidney business. Drives the financial performance management process for responsible functions (objective setting, budget vs. actuals, etc.), including the monthly forecast process, with a focus on influencing business operations and decisions through an understanding of the key drivers of short term performance and communicating the range of possible outcomes. Drives the financial planning process for responsible functions (budget, forecast, long range plan) to provide insightful and influential forward looking direction, to develop key scenarios, and to identify key risks/uncertainties and plans for potential mitigation. Works closely with other members of the CFO organization including to maintain a continuous improvement mindset and promote strong communication, sharing of best practices and efficient processes. Identifies and help drive opportunities to improve process across the global finance organization. Ensure financial integrity, sound governance, and compliance across all areas of responsibility. Help define and monitor business KPIs that support strategic decision-making and identify opportunities to expand patient access in the U.S. Knowledge and Skills: Demonstrated experience in the pharmaceutical industry, including finance business partnering with senior or executive leaders. Strong financial, analytical, and problem-solving skills, with the ability to evaluate complex business issues and investment decisions. Experience with portfolio analysis, valuation, ROI/ROIC assessment, forecasting, and broader commercial finance support. Strong communication, influencing, and interpersonal skills, with the ability to work effectively across senior leadership, Finance, and cross-functional teams. Ability to lead through change in a dynamic business environment involving complex processes, multiple stakeholders, and tight timelines. Proven ability to operate effectively in a cross-functional, matrixed, and global organization. Strong proficiency in Microsoft Office and financial systems, including Hyperion. Broad understanding of the pharmaceutical industry and the ability to address business challenges across functions. Demonstrated leadership capability to build, lead, or develop high-performing business partnerships and teams. Education and Experience: Bachelors Degree in Finance or Accounting. Typically requires 8 years of relevant financial experience or the equivalent combination of education and experience. A track record of success working in a team-based environment. #LI-MF1 #HYBRID Pay Range: $134,400 - $201,600 Disclosure Statement: The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more. Flex Designation: Hybrid-Eligible Or On-Site Eligible Flex Eligibility Status: In this Hybrid-Eligible role, you can choose to be designated as: 1. Hybrid: work remotely up to two days per week; or select 2. On-Site: work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time. #LI-Hybrid Company Information Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at View email address on click.appcast.io Help Us Achieve Our Mission Vertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious diseases. The company has approved medicines that treat the underlying causes of multiple chronic, life-shortening genetic diseases — cystic fibrosis, sickle cell disease and transfusion-dependent beta thalassemia — and continues to advance clinical and research programs in these diseases. Vertex also has a robust clinical pipeline of investigational therapies across a range of modalities in other serious diseases where it has deep insight into causal human biology, including APOL1-mediated kidney disease, acute and neuropathic pain, type 1 diabetes, myotonic dystrophy type 1 and alpha-1 antitrypsin deficiency . Founded in 1989 in Cambridge, Mass., Vertex's global headquarters is now located in Boston's Innovation District and its international headquarters is in London. Additionally, the company has research and development sites and commercial offices in North America, Europe, Australia, Latin America and the Middle East. Vertex is consistently recognized as one of the industry's top places to work, including 14 consecutive years on Science magazine's Top Employers list and one of Fortune’s 100 Best Companies to Work For. For company updates and to learn more about Vertex's history of innovation, visit or follow us on Facebook, Twitter/X , LinkedIn, YouTube and Instagram. The diversity and authenticity of our people is part of what makes Vertex unique, and we recognize that each employee brings diverse perspectives and strengths. By embracing those strengths and celebrating differences, we are fostering an inclusive culture where each of us can bring our authentic selves to work, inspire innovation together, and change people’s lives. Our vision is clear: to be the place where an authentic, diverse mix of talent want to come, to stay, and do their best work.