Sr Director, Medical Affairs (Obesity and Metabolic Programs)

Position Summary

Reporting to the Executive Director, Medical Affairs & Advocacy Engagement, the Senior Director, Medical Director at Structure Therapeutics will lead the development and execution of the Medical Strategy, gathering and synthesizing external insights—including treatment patterns, unmet medical needs, and competitive intelligence—across all metabolic programs.

This role is critical in shaping scientific engagement and communications, identifying evidence gaps, and supporting lifecycle management. The individual will serve as a key scientific expert internally and externally, ensuring alignment across clinical development, regulatory, and commercial readiness efforts.

As a trusted scientific partner, the Medical Director builds and sustains relationships with key opinion leaders, investigators, healthcare professionals, and patient communities, facilitating the exchange of scientific information related to the company’s pipeline and therapeutic focus areas. The role requires a high level of expertise in interpreting and communicating clinical and translational data, particularly in fast‑evolving therapeutic landscapes.

The Medical Director plays a pivotal role in supporting clinical development programs by identifying and engaging top investigators and providing key insights that inform study design and execution.

Job Responsibilities

Medical Strategy

• Develop and execute a comprehensive Medical Strategic Plan, including insight generation, data dissemination, and medical communications, across all obesity and related metabolic programs
• Lead Publication Strategy across all programs (abstracts, manuscripts, congress presentations)

Scientific & External Engagement

• Build relationships with Key Opinion Leaders (KOLs), academic institutions, and healthcare providers
• Present clinical and scientific data on metabolic therapies and represent the company at medical and community congresses, advisory boards
• Lead high‑level scientific discussions on disease state and treatment landscape

Evidence Generation & Insights

• Support Investigator‑Initiated Trials (IITs) and real‑world evidence studies
• Gather and synthesize medical insights from HCP interactions
• Inform clinical development plans and lifecycle management

Cross‑Functional Collaboration

• Partner with:
  • Clinical development (trial design considerations, medical insights, unmet medical need)
  • Clinical Operations (investigator needs and engagement)
  • Market access (value messaging)
  • Commercial teams (compliant scientific support)
• Review materials for scientific accuracy and compliance as representative in Medical Legal Regulatory (MLR) review process
• Ensure all activities comply with regulatory and ethical standards

Qualifications

Education

• MD, PharmD, or PhD in a relevant scientific field

Experience

• 10+ years in biotech/pharma
• Strong background in metabolic diseases (e.g., obesity, type 2 diabetes), global experience a plus
• Prior experience as Medical Director or equivalent in Medical Affairs

Skills

• Deep scientific expertise in metabolism. Direct experience in obesity, type 2 diabetes, or incretin‑based therapies is preferred
• Experience with protocol design in metabolism, particularly incretin therapies
• Strong communication and presentation skills
• Leadership and team management ability
• Strategic thinking with execution focus

Travel Requirements

• Regional or national coverage
• Travel (25%) for HCP engagement and conferences, corporate meetings

Compensation & Benefits

Structure Therapeutics offers a base pay range of $260,000–$365,000, with compensation depending on geography, qualifications, and experience. The position can be on‑site or remote.

In addition to base pay, the successful candidate will be eligible for an annual performance incentive bonus, new‑hire equity, and ongoing performance‑based equity. Benefits include medical, dental, and vision insurance, 401(k) match, unlimited PTO, and paid holidays, including a winter shutdown.

Equal‑Opportunity Employer

Structure Therapeutics Inc. is an Equal‑Opportunity Employer.