Senior Scientist, Targeted Protein Degradation
Amgen
Amgen seeks a Senior Scientist to advance E3 ligase biology and molecular glue discoveries within the IPP program in Thousand Oaks, CA. You will drive screening and validation of degraders, identify novel targets, and translate findings into therapeutic opportunities. You will work across disciplines, leveraging oncology, immunology and cardiovascular biology insights to push forward high‑value targets, collaborate with chemistry and proteomics teams, and publish impactful results. #J-18808-Ljbffr Amgen
- Amgen in Thousand Oaks is seeking a Senior Scientist to advance targeted protein degradation, focusing on E3 ligases and molecular glue strategies. You will design screening workflows and validate hits, driving discovery of novel targets in oncology and related fields....Senior
$127.12k - $171.99k
...transform the lives of patients while transforming your career.Senior Scientist - Targeted Protein DegradationWhat you will doLet’s do this. Let’s change... ...disease areas.Within IPP, the Targeted Protein Degradation function integrates E3 ligase biology, chemical biology...SeniorFull timeFlexible hours$140.12k - $189.58k
...of the Amgen team. Join us and transform the lives of patients while transforming your career.Principal Scientist - Lead Discovery and Targeted Protein Degradation BiochemistryWhat you will doLet’s do this. Let’s change the world. In this role, you will lead protein reagent...SuggestedFull timeFlexible hours- Aequor is seeking a Sr Associate onsite in Thousand Oaks, CA to join the Protein Therapeutics - Protein Chemistry team. You will support the analysis and characterization of large molecule biologics and contribute to purification and analytics to advance lead candidates...Senior
- Amgen in Thousand Oaks, CA is seeking a Process Development Senior Scientist to lead analytical and biochemical characterization for pre-clinical biotherapeutic protein development, including mass spectrometry and LC-MS workflows. You will develop methods to assess biochemical...Senior
- ..., youll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career. Senoir Scientist, Protein Therapeutics Mammalian Expression & Cell Line Engineering What You Will Do Lets do this. Lets change the world. In this vital...SeniorFlexible hours
- Amgen in Thousand Oaks seeks a Senior Scientist in Protein Biochemistry to drive design, expression, and purification of proteins for structural biology projects (X-ray, cryo-EM). You will collaborate with structural biologists to deliver high-quality samples for structural...SeniorFlexible hours
- Amgen is seeking a Senior Scientist in Cardiometabolic Disorders to drive biology research, identify therapeutic targets, and guide drug discovery programs. The role combines bench science with leadership, focusing on osteoporosis and metabolic disease, with opportunities...Senior
- Amgen Inc. (IR) in Thousand Oaks recruiting a Senior Scientist to lead automation for functional genomics screens and multi-omics integration... ...therapeutic areas, optimize imaging assays, and advance target discovery strategies in a fast-paced, science-driven environment...Senior
- Amgen in Thousand Oaks, CA is seeking a Senior Scientist in Functional Genomics to drive genome engineering for target discovery and validation. You will design and apply viral vector technologies (AAV, lentiviral) in multidisciplinary discovery teams, translating complex...Senior
- Amgen in Thousand Oaks, CA, is seeking a Senior Scientist in mass spectrometry-based proteomics to join a collaborative team. You will deliver insights to support target identification and drug discovery, while advancing proteomics platforms. The role includes developing...Senior
- Amgen Inc. (IR) in Thousand Oaks seeks a Senior Scientist to drive automation and HTS for target discovery and biology. You will lead automation pipelines, translate manual protocols to 96- and 384-well formats, and optimize imaging and data analysis in state-of-the-art...Senior
- ...ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career. Senior Scientist, Automation and HTS - Target Discovery & Biology (TD&B) What you will do Let’s do this. Let’s change the world. In this vital role you will...SeniorRemote workFlexible hours
$134.14k - $181.48k
...transform the lives of patients while transforming your career.Senior Scientist - Protein BiochemistWhat you will doLet’s do this. Let’s change the... ...reagents that support the structure determination of target molecules via X-ray crystallography and/or cryo-electron microscopy...SeniorFull timeFlexible hours- Amgen is seeking a highly motivated Scientist to join the Thousand Oaks, CA team. This role focuses on developing and deploying novel molecular... .... You will work within a multidisciplinary group integrating protein engineering and analytical methods, contributing to robust,...Senior
- Amgen in Thousand Oaks, CA is seeking a Senior Scientist to advance synthetic biology, molecular engineering and NGS within our Protein Therapeutics team. You will help develop and deploy novel workflows that enable rapid, scalable design of complex biologic molecules in...Senior
$127.12k - $171.99k
...Amgen team. Join us and transform the lives of patients while transforming your career.Senior Scientist - Functional GenomicsWhat you will doThe Functional Genomics group within Target Discovery and Biology (TD&B) is seeking a highly motivated Senior Scientist to develop...SeniorFull timeFlexible hours- ...transforming your career. Sr Scientist What You Will Do Lets do... ...We are seeking a motivated Senior Scientist in mass spectrometrybased... ...insights to support target identification and drug discovery... .... Knowledge of targeted protein degradation or E3 ligase biology is a plus...SeniorFlexible hours
- Amgen is seeking a Process Development Senior Principal Scientist to lead a multidisciplinary team focused on bioconjugate manufacturing process development for antibody-drug conjugates (ADCs) at the Thousand Oaks campus. The role emphasizes innovation, scalability, and...Senior
- Amgen is seeking a Process Development Senior Principal Scientist to lead a team of analytical scientists, developing, transferring, validating, and implementing analytical methods for late-stage oligonucleotide programs through commercialization. You will shape analytical...Senior
- Amgen is seeking a Process Development Senior Principal Scientist in Thousand Oaks, CA to lead drug product design, formulation, and process development for biologics and ADCs. You will guide diverse teams through scale‑up, characterization, and regulatory readiness to...Senior
$168.39k - $227.83k
...you'll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career. Senior Principal Scientist What you will do Let's do this. Let's change the world! We are seeking an experienced toxicologist in the Product...SeniorWork at officeRemote workFlexible hours- Amgen is seeking a Process Development Senior Scientist - Drug Product Technologies to lead early-stage ADC formulation and drug product development. You will design and optimize liquid and lyophilized formulations, drive CQAs, and enable scalable fill/finish processes...Senior
- Amgen is seeking a Process Development Senior Scientist to lead drug product development and execution for early clinical synthetic molecule programs. You will design robust formulations and work with internal and external partners to enable scale-up and GMP manufacturing...Senior
- US Tech Solutions is seeking a hands-on bioanalytical Scientist with strong large-molecule experience to develop, validate, and implement robust ligand-binding assays (ELISA/ECL) for clinical and nonclinical samples. The role requires collaboration across cross-functional...Senior
- US Tech Solutions is seeking a detail-oriented analytical scientist for a 36-month contract in Thousand Oaks, CA. The role involves performing analytical testing (HPLC/UHPLC, IEX, SEC, CE) and protein characterization under guidance, with an emphasis on high-quality documentation...Contract work
- Amgen in Thousand Oaks seeks a Senior Scientist in Protein Biochemistry to lead design, planning, and execution of reagents for structure determination by X-ray crystallography and cryo-EM. You will collaborate with structural biologists to advance drug discovery and apply...
- Amgen is seeking a Process Development Senior Scientist, Drug Product Technologies, to drive formulation, stability, and process development for diverse biologics including ADCs and oligonucleotides. You will integrate formulation, analytical data, and manufacturing considerations...Senior
- Amgen is seeking a Senior Scientist in Functional Genomics to develop genome engineering technologies and expand functional genomics capabilities across discovery programs. You will collaborate with multidisciplinary teams to translate advanced technologies into discoveries...Senior
- Amgen is seeking a Principal Scientist in Inflammation Human Data & Computational Biology to accelerate discovery with deep wet-lab and... ...diverse data sources and guiding experimental design. We expect senior researchers with PhD/MD/PharmD and substantial industry experience...Senior
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