Senior Principal Scientist, Analytical Chemistry

Senior Principal Scientist, Analytical Chemistry Working with Us Challenging. Meaningful. Life‑changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high‑achieving teams. Take your career farther than you thought possible. Team Overview Our Analytical Science and Operations team creates transformative medicines for tomorrow based on the cutting‑edge science of today. Working within Global Product Development and Supply, this team uses state‑of‑the‑art technologies to develop, enable and execute analytical and CMC strategies that ensure safety, quality and efficacy of life‑saving medicines administered to patients in clinical studies. Our team is involved at the earliest stages of pharmaceutical and biopharmaceutical product development through successful commercial launch. Position Summary The Senior Principal Scientist will serve as a CMC Analytical Lead (CMC‑AL) for drug candidates across all stages of development, and within the commercial product portfolio as needed. This role is a key member of cross‑functional CMC teams responsible for analytical strategy development. The incumbent will collaborate across functions to identify critical quality attributes (CQAs) for drug substance and drug product and establish control strategies to ensure product quality. The role drives analytical controls in alignment with ICH guidelines and global regulatory requirements and has significant influence across the division and broader organization. Role and Responsibilities Lead analytical strategy development as a core member of cross‑functional CMC teams. Define product critical quality attributes and establish methods, specifications, and analytical control strategies. Collaborate across Analytical, Drug Substance, Drug Product, Quality, and Regulatory functions. Review, interpret, and communicate analytical results and conclusions. Author, review, and approve technical reports to support regulatory submissions. Respond to regulatory authority questions related to analytical strategy and data. Provide leadership, coaching, and mentoring to scientific staff within matrix teams. Required Qualifications BS with 12–15 years, MS with 9–12 years, or PhD with 6–8 years of pharmaceutical experience in chemistry or related discipline. Demonstrated scientific accomplishments including publications and presentations. Experience with GMP and GLP requirements and risk assessment processes. Strong expertise in synthetic chemistry, drug substance and drug product development. Extensive experience in analytical method development, validation, and technical transfer. Experience with analytical testing across diverse dosage forms. Knowledge of dissolution methods and biopharmaceutical assessment. Familiarity with ICH and global regulatory requirements. Experience supporting regulatory submissions and building CMC dossiers. Experience with commercialization of small molecule drug products. Experience managing external manufacturing and testing labs. Preferred Qualifications Strong communication and interpersonal skills. Experience working in matrixed team environments. Familiarity with modern laboratory equipment and automation. Knowledge and application of Quality by Design (QbD) principles. Compensation Overview New Brunswick - NJ - US: $135,950 - $164,738. The starting compensation range(s) for this role are listed above for a full‑time employee (FTE) basis. Additional incentive cash and stock opportunities (based on eligibility) may be available. The starting pay rate takes into account characteristics of the job, such as required skills, where the job is performed, the employee’s work schedule, job‑related knowledge, and experience. Final, individual compensation will be decided based on demonstrated experience. Benefits Health Coverage: Medical, pharmacy, dental and vision care. Well‑being Support: Programs such as BMS Well‑Being Account, BMS Living Life Better and Employee Assistance Programs (EAP). Financial Well‑being and Protection: 401(k) plan, short‑ and long‑term disability, life insurance, accident insurance, supplemental health insurance, business travel protection, personal liability protection, identity theft benefit, legal support and survivor support. Paid Time Off and Flexibility US Exempt Employees: flexible time off (unlimited, with manager approval) and 11 paid national holidays. Phoenix, AZ, Puerto Rico and Rayzebio Exempt, Non‑Exempt, Hourly Employees: 160 hours annual paid vacation for new hires with manager approval, 11 national holidays and 3 optional holidays. Additional time off may include unlimited paid sick time, up to 2 paid volunteer days per year, summer hours flexibility, leaves of absence for medical, personal, parental, caregiver, bereavement and military needs, and an annual global shutdown between Christmas and New Year’s Day. On‑Site Protocol Occupancy type is determined by the nature and responsibilities of the role. Site‑essential roles require 100% of shifts onsite at the assigned facility. Site‑by‑design roles may be eligible for a hybrid model with at least 50% onsite. Field‑based and remote‑by‑design roles require sufficient travel to meet customer, patient or business partner needs. Supporting People With Disabilities BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations and ongoing support. Applicants can request accommodations prior to accepting an offer. For more information, visit careers.bms.com/eeo-accessibility. Candidate Rights BMS will consider qualified applicants with arrest and conviction records, pursuant to applicable laws in your area. Data Protection BMS will never request payments, financial information or social security numbers during the application or recruitment process. Learn more about protecting yourself at careers.bms.com/fraud-protection. Any data processed in connection with role applications will be treated in accordance with applicable privacy policies and regulations. Recruitment Contacts For any application‑related inquiries, direct questions to View email address on click.appcast.io. 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