Analytical Chemist - Energetics & Process Development
$120k - $160kApproach Venture LLC
Analytical Chemist - Build the Chemistry Behind Next-Generation Manufacturing
Waltham, Massachusetts | On-site
Opportunity Summary
Join an early-stage advanced manufacturing company developing new chemical production processes for critical defense applications. The team is building highly automated manufacturing systems designed to take complex chemistry from laboratory development through pilot-scale production and ultimately into repeatable, high-rate manufacturing. As an Analytical Chemist, you will own much of the analytical foundation behind that effort. You will develop methods for characterizing reaction intermediates, impurities, raw materials, and finished products, while working closely with process scientists and engineers as chemistry moves from the bench into larger-scale production. This is not a routine testing or established QC role. Many of the analytical methods, workflows, and laboratory systems still need to be created. You will have significant ownership over how chemistry is measured, understood, validated, and ultimately qualified for production.
About Us
We are a venture-backed advanced manufacturing company applying modern chemistry, automation, and process engineering to an industry where manufacturing technology has changed relatively little for decades. Our work combines hands-on experimental chemistry with automated production systems to create safer, more scalable manufacturing capabilities for national security applications. The company is moving quickly from development into pilot-scale production, giving chemists the opportunity to see their work progress from early experimentation through real-world manufacturing.
Job Duties
- Own analytical method development and product characterization across chemical R&D and process development programs
- Develop and validate HPLC, GC, LC-MS, and related chromatographic methods for intermediates, impurities, and finished materials
- Develop quantitative NMR methods to evaluate reaction conversion, composition, and process performance
- Use DSC, TGA, FTIR, microscopy, laser diffraction, and related techniques to characterize material properties, thermal behavior, particle size, and morphology
- Establish analytical approaches for chemistry and materials where established test methods may not yet exist
- Partner directly with chemists and process engineers to understand reaction behavior, identify failure modes, and improve manufacturing processes
- Support experimental chemistry as processes move from laboratory-scale development into pilot-scale production
- Build analytical data packages supporting product qualification, first-article acceptance, and regulatory or customer documentation
- Specify, procure, install, commission, and qualify laboratory instrumentation
- Establish calibration, standards, reproducibility, LOD/LOQ, and instrument-quality practices across the chemistry laboratory
- Write SOPs, analytical procedures, validation protocols, and technical documentation from the ground up
- Investigate discrepancies in analytical results and determine whether root causes originate from chemistry, process conditions, hardware, sampling, or analytical methods
- Support applicable military or industry testing requirements in coordination with internal technicians and external laboratories
- Build or improve data-analysis workflows that allow scientists and engineers to quickly interpret current results and compare historical process data
- Maintain a high standard for analytical reproducibility and data quality across the laboratory
- Periodically support chemistry development and testing at a nearby pilot manufacturing facility
Qualifications
- B.S., M.S., or PhD in Analytical Chemistry, Chemistry, Organic Chemistry, Chemical Engineering, or a closely related discipline
- Strong hands-on analytical chemistry background with experience developing methods rather than exclusively executing established procedures
- Experience with analytical techniques such as HPLC, GC, LC-MS, NMR, FTIR, DSC/TGA, IC, ICP, or comparable instrumentation
- Experience validating analytical methods and establishing repeatable testing procedures
- Strong understanding of analytical accuracy, precision, calibration, reproducibility, detection limits, and instrument performance
- Ability to troubleshoot instruments, analytical methods, experimental procedures, and unexpected chemistry results
- Comfortable working directly in laboratory and pilot manufacturing environments
- Strong quantitative skills and the ability to interpret complex experimental data
- Ability to operate independently in an environment where procedures, infrastructure, and analytical standards are still being developed
- Strong written communication skills for SOPs, test procedures, technical reports, and qualification documentation
- U.S. Person as defined by applicable U.S. export-control regulations
- Ability to obtain a U.S. security clearance
- Ability to work on-site and travel periodically between development and pilot facilities
- Ability to lift up to 50 pounds
Preferred Experience
- Analytical chemistry experience supporting energetic materials, propellants, explosives, specialty chemicals, pharmaceuticals, or other tightly controlled chemical manufacturing environments
- Experience supporting chemical process development from laboratory scale into pilot or production environments
- Background investigating reaction intermediates, impurities, degradation products, or process chemistry
- Experience establishing an analytical laboratory or selecting and commissioning instrumentation
- Familiarity with military specifications, qualification testing, first-article testing, or regulated product acceptance
- Experience with high-hazard or highly regulated chemical systems
- Experience automating analytical data processing, visualization, or laboratory workflows
- Exposure to statistical process control, design of experiments, or manufacturing-quality systems
- Experience working in an early-stage company, R&D organization, national laboratory, or other environment requiring significant technical ownership
- Demonstrated interest in moving scientific work beyond benchtop research and into scalable manufacturing
Why Join Us
- Own analytical chemistry within a technically challenging manufacturing environment
- Develop methods and laboratory capabilities rather than simply inherit established procedures
- Work directly across chemistry, process development, automation, and manufacturing
- See experiments progress from the laboratory into pilot-scale and production hardware
- Join at an early stage where individual scientists can have significant influence over technical direction and laboratory standards
- Equity participation through company stock or stock options
- Eligibility for discretionary individual and company performance bonuses
- Comprehensive medical, dental, and vision coverage
Compensation Details
$120,000 - $160,000
$120k - $145k
...Description Job Description AT Process Technologies (ATP) is a... ...manufacturing company focused on the development and deployment of modular energetics production plants. Using breakthrough... ...We are seeking an experienced analytical chemist who will own the product...SuggestedPermanent employment- ...AT Process Technologies (ATP) is a pioneering manufacturing... ...company focused on the development and deployment of modular energetics production plants. Using... ...a process development chemist to own and execute the research... ...practices Basic analytical chemistry experience (NMR...SuggestedPermanent employment
- ...AT Process Technologies (ATP) is a pioneering manufacturing... ...company focused on the development and deployment of modular energetics production plants. Using... ...are seeking a synthetic chemist to lead small-scale... ...reactions through off-line analytical method development and in...SuggestedPermanent employment
- Pacelabs is seeking a dedicated laboratory scientist to support development and validation of chromatographic methods and mass spectrometric assays for siRNA with GMP experience. The role involves hands-on bench work with High-Resolution LC-MS, method development, impurity...SuggestedMonday to Friday
- ...ahead capability in support of national security. Our materials research enterprise spans the materials development cycle from computation and theory to growth, processing, and characterization, and complements RF, imager, and quantum computing technology development in...Suggested
$82.3k - $220k
Overview:Draper is an independent, nonprofit research and development company headquartered in Cambridge, MA. The 2,000+ employees of Draper... ...salary range for your preferred location during the hiring process. Please note that the compensation details listed in US role...Full timeLocal area$94k - $115k
Job Description:Analytical Chemist - 2nd ShiftBurlington, MAABOUT THE COMPANY:QSA Global, a division... ...oil well logging (OWL), industrial processes, and nuclear medicine. With more than... ..., quality assurance, product development, and regulatory compliance. This role...Work experience placementLocal areaAfternoon shift- Scorpion Therapeutics seeks a Formulation and Process Development Scientist to advance early-stage biopharmaceutical platforms focusing on dried powder formulations. You will design mixing protocols, produce and characterize powders, and document processes to enable scalable...
$100k - $120k
...Analytical Chemist Boston, MA ( Description Living Proof is seeking an experienced and... ...Responsibilities include analytical method development and validation, investigating complex... ...methods for raw materials, in-process samples, and finished hair care products...Full timeContract work- ...integrity at our core, we lead federally funded research and development centers for U.S. government agencies - collaborating with industry... ...theory, error control coding, information theorystochastic processes, propagation, channel estimation and equalizationreceiver design...InternshipLocal area3 days per week
- ...impact the course of our national defense strategy. The solutions we develop within the group often lead to advanced technology development, prototyping projects, and experimental testing, both within Lincoln Laboratory and beyond. The group’s staff are the key to the...
$115k - $165k
...accelerate drug discovery and development.The Small Molecules team is... ...for a synthetic organic chemist to support computationally enabled... ..., stoichiometry, outcomes, analytical data, and negative results.... ....Experience with inline or process monitoring such as ReactIR,...Work at office$91.5k - $95k
...Description:The Scientist is responsible for performing advanced analytical development activities with a primary focus on hands-on operation of... ...principles, theories, concepts, practices and standards to process and analytical development.Follow training to independently...Full timeWork at officeLocal areaImmediate startMonday to FridayFlexible hoursShift work- ...seeking a talented and creative medicinal chemist with a strong track record of advancing... ...projects from initial hits through to development candidate selection to join our dynamic... ...and project success by interpreting analytical results to confirm compound quality....
$95k - $245k
...an independent, nonprofit research and development company headquartered in Cambridge, MA.... ...and non-technical personnel. Excellent analytical skills to support modeling and analysis... ...your preferred location during the hiring process. Please note that the compensation...Full timeLocal area$40 - $50 per hour
...Overview: The Formulation Scientist will support solid oral dosage development in a Quality by Design (QbD) environment. The Formulation... ...across lab and clinical manufacturing scale, turning materials and process data into robust formulations. This is an excellent...Hourly pay$148k - $208k
...will involve technical safety strategy development, broader ecosystem engagement, safety-focused... ...systems. We are seeking a chemist to map risk across the chemical sciences... ...and organometallic chemistry, synthesis, process development and formulations, or other relevant...Full timeWork at officeLocal areaFlexible hours$121.28k - $202.13k
...oligonucleotide synthesis lab as a process discovery chemist, bridging early discovery-stage chemistry... ...-to-gram scale, building out method development and chromatography/purification... ...grade material. Partner with the oligo analytical and conjugate chemistry teams to...Full timeLocal area$150k - $180k
...bioinformatics, data science, engineering, and drug development, our multidisciplinary team in Toronto... ...in Cambridge, MA is focused on the analytical characterization and formulation of... ...from such data. Perform formulation processes to provide research samples ready for...Local areaFlexible hoursWeekend work- ...to reversing climate change through the development and deployment of advanced technology. The company’s proprietary electro-swing process, developed at MIT, enables carbon dioxide... ...our vision. Verdox seeks a Polymer Chemist to join our R&D team. Key Responsibilities...
$85k - $110k
...presenting great opportunities for personal development and career advancement across the globe... ...-and-test lab, automated synthesis, analytical characterization, and biological... ...up of a synthetic route or purification process from milligram to multigram scale. Analytical...Full timeFor contractorsFlexible hours- Anika is seeking a QC Analyst II to perform analytical testing and support raw materials, in‑process and finished goods under cGMP. This role develops expertise in analytical methods, instrumentation, and quality control within regulated pharma/medical device environments...
- ...seeks a Formulation Scientist to advance early-stage product development focused on dried powder formulations via lyophilization and spray... ..., produce and characterize dried powders, and help scale processes for tech transfer. The role emphasizes independent experimental...
$100k - $115k
...Senior Manufacturing Chemist Billerica, MA (on-site) Quanterix... ..., diagnostics, and drug development. Its proprietary Simoa® technology... ...on supporting manufacturing processes, equipment, and... ...processing Knowledge of analytical testing methods (e.g., titration...Full time$230k - $300k
...and manages a comprehensive Quality Management Program that monitors and evaluates critical radiation oncology equipment and processes and strives to optimize them. ~ Maintains professional contact with peers through professional association membership, attendance...Work experience placementLocal area$36 - $48.45 per hour
...written procedures. Appropriately follow procedure for sample processing. Perform follow-up procedures on rejected/missing samples according... ...to Medical Lab Scientist 2. Skills, Knowledge & Abilities Analytic ability to perform moderately complex tests, interpret...Hourly payShift work$32 - $36 per hour
...international life sciences company, providing a unique range of analytical testing services to clients across multiple industries, to... ..., as well as having an emerging global presence in Contract Development and Manufacturing Organisations. It also has a rapidly developing...Full timeContract workMonday to Friday$118k - $145k
...Scientist, RNA Chemistry contributes to the development of Dyne’s oligonucleotide chemistry... ...of various lengths. Interpretation of analytical data (HPLC, LCMS) to enable improved... ...rationally perform the hit-to-lead optimization process. Generate intermediates to prepare...Local area- QSA Global, a division of ITW, is seeking an Analytical Chemist for 2nd shift in Burlington, MA. You will develop and validate analytical methods, perform ICP-OES/ICP-MS testing, and ensure QA/QC compliance to support radiochemistry manufacturing and regulatory requirements...Afternoon shift
$120k - $168k
..., embedded systems, and advanced assay development. Our chip-based solution integrates state... ...device. We are seeking an exceptional Chemist or Senior Chemist with solid expertise... ...chemistry schemes, validate them using analytical tools and internal assay configurations...Work at officeFlexible hours
Do you want to receive more vacancies?
Subscribe and receive similar vacancies to Analytical Chemist - Energetics & Process Development. Be the first to apply!
- graduate development program Waltham, MA
- career development Waltham, MA
- game development intern Waltham, MA
- professional development program Waltham, MA
- vice president research and development Waltham, MA
- development accountant Waltham, MA
- vice president development Waltham, MA
- franchise development Waltham, MA
- entry level child development Waltham, MA
- vice president real estate development Waltham, MA



