Principal Electrical Systems Engineer
SiPhox Health
SiPhox Health is transforming clinical diagnostics by integrating silicon photonics, microfluidics, embedded electronics, and semiconductor manufacturing into a compact, consumer-ready diagnostic platform. Our system orchestrates optics, fluidics, motors, pumps, heaters, sensors, and multiple microcontrollers to deliver high-precision biomarker measurements at home. The electrical system is the backbone of the platform. Every movement, every optical read, every thermal transition, and every pump actuation depends on robust, reliable, safety-controlled electronics. +++ The Opportunity +++ We are hiring a Principal Electrical Systems Engineer to architect, design, and scale the electronics that power the entire SiPhox diagnostic instrument. You will define and own the electronics that unify the motion system, camera module, pumps, heaters, stepper motors, encoders, valves, sensors, and photonic reader into a cohesive medical-grade device. This is a role for an engineer who thrives at the intersection of mixed-signal design, motor control, power electronics, embedded interfaces, and system-level reliability. Your work will directly enable the world’s first mass‑market photonic blood analyzer. +++ What You Will Do +++ System Architecture and PCB Design Own the electrical architecture for the full diagnostic instrument, including: Stepper and BLDC motor drivers Pump and valve control Linear actuators and gantry control Camera and LED subsystem Centrifuge motor with encoder feedback Resistive heater and NTC sensing SPI‑connected photonic reader MCU Power distribution and external PSU integration Lead schematic design, PCB layout, component selection, and design documentation Develop mixed‑signal circuits for optical sensing, thermal control, motor control, and fluidic actuation Ensure designs meet performance, safety, EMC, and reliability requirements for medical devices Embedded Hardware Integration Collaborate closely with firmware engineers (ESP32 and STM32) on HAL requirements, timing constraints, and motor‑control behavior Support real‑time interfaces including SPI, UART, RS485, USB, and GPIO triggers Validate hardware communication with the Linux SBC, reader subsystem, motion modules, and cartridge heater system Electromechanical and Motion Integration Architect and tune electronics for: Multi‑axis gantry (X, Y, Z) Centrifuge with incremental encoder Lift slider and drawer motor Camera trigger and illumination control Lead hardware bring‑up, system debug, and cross‑functional root‑cause analysis for motion, thermal, and sensing issues Reliability, Safety, and Compliance Own electrical risk analysis and contribute to FMEAs and hazard controls Design for IEC 60601, IEC 61010, ISO 13485, and relevant diagnostic device standards Implement electrical protections, safety interlocks, and fault‑tolerant behavior Drive EMC testing, mitigation, and design improvements Manufacturing and Scale‑Up Work with suppliers, CM partners, and PCB fabrication houses Design automated test fixtures and production validation tools Improve yield, robustness, and cost efficiency as the platform scales +++ What We Are Looking For +++ Required Experience Deep experience designing electronics for complex electromechanical or instrumentation systems Strong background in stepper, servo, or BLDC motor control electronics Expertise with sensors, encoders, heaters, NTCs, and precision analog signaling Proficiency with PCB design tools such as Altium Familiarity with SPI, USB, RS485, UART, CAN, and other real‑time interfaces Experience designing for EMC, safety, and regulatory compliance Bachelor’s or Master’s in Electrical Engineering or related field Authorized to work in the U.S. and available onsite in Burlington, MA Highly Desirable Medical device, IVD, or laboratory instrument experience Experience with fluidic or motion‑system electronics Experience with power systems and external PSU integration Experience with automated manufacturing test systems Experience working with microcontrollers (ESP32, STM32, NXP) +++ Why This Role Is Unique +++ Design the electronics backbone for the first at‑home photonic diagnostic platform Integrate optics, fluidics, motion, sensing, and thermal control into one cohesive system Build hardware that directly impacts diagnostic accuracy and patient outcomes See your work ship in a consumer device used by real people, at scale If you want to architect the electronics that power the future of home diagnostics, we want to meet you. Seniority level Mid‑Senior level Employment type Full‑time Job function Engineering, Research, and Design Industries Medical Equipment Manufacturing, Hospitals and Health Care, and Wellness and Fitness Services Referrals increase your chances of interviewing at SiPhox Health by 2x. #J-18808-Ljbffr SiPhox Health
$116.5k - $166.5k
...join our iRobot Labs innovation team within the R&D engineering organization. We are looking for a Principal Robotics Engineer who thrives in a fast-paced,... ...innovation initiatives through subject matter guidance, system design and development of robots and robotic...PrincipalSecond jobWork visa- ...Product Development Engineer Join us at Berkshire Grey to deliver best-in-class robotic... ...into production and supporting deployed systems. We're looking for self-starters who can... .... Qualifications BS or MS in Electrical Engineering or similar (e.g. Mechatronics...PrincipalWork experience placementImmediate start
- Werfen North America is seeking a Principal Compliance Engineer in Bedford, MA, to serve as the technical authority on compliance for EMI, EMC, and Electrical Safety across the Hemostasis and Acute Care Diagnostics product lines. This role will require strategic oversight...Principal
$149.99k - $191.65k
...Principal Electrical Engineer Req Id: 434 Location: Billerica, MA, US, 01821 Date: Jul 6, 2026 Thales... ...capability, advanced radars, undersea sensing and missile systems. Lives depend on what we do! Top Benefits (Subject...PrincipalWork experience placementWork at officeLocal areaImmediate start$160k - $200k
...than 7,000 strong. Job Summary The Principal Compliance Engineer is the Hemostasis and Acute Care Dx business... ...authority for EMI, EMC, and Electrical Safety. Candidate ensures timely planning... ...as needed, while operating at a system‑ and portfolio‑level to guide design...PrincipalWork experience placementWorldwide- Teledyne FLIR is seeking a Sr. Electrical Systems Manufacturing Engineer in Billerica, Massachusetts. The role focuses on transitioning new products into operations and resolving technical issues in production. Candidates should have a Bachelor’s degree in Electrical Engineering...
- ...Principal Electrical Engineer The Radar Digital Products Department is seeking a Principal Electrical Engineer with strong mixed signal high speed... ...digital circuit design skills. Our digital electronic system designs include signal processing, command and control, communications...PrincipalWork at officeRelocation
- A leading engineering services company is seeking a Senior Principal Systems Engineer to provide technical advice and support for advanced weapon systems at Hanscom Air Force Base. The ideal candidate has over 15 years of relevant experience, particularly in acquisition...Principal
$107.5k - $204.5k
...our world. The Radar Digital Products Department is seeking a Principal Electrical Engineer with strong mixed signal high speed digital circuit design skills. Our digital electronic system designs include signal processing, command and control, communications,...PrincipalTemporary workWork experience placementWork at officeRemote workRelocationFlexible hours$107.5k - $204.5k
Position: Principal Electrical Engineer (Onsite). Location: Tewksbury/Andover, MA. Security Clearance: Secret. We are looking for a Principal Electrical... ...‑career staff. Knowledge of RTX projects, programs or systems to make enhancements and leverage in daily work....PrincipalTemporary workWork at officeRemote workFlexible hours$115k - $165k
Position Summary The Principal Manufacturing Engineer is a hands‑on technical leader responsible for new product introduction and for defining, validating... ...Requirements Bachelor’s degree in Mechanical, Electrical, Manufacturing, Biomedical Engineering, or related field...PrincipalContract workWork experience placement- Cadence is seeking a Senior Engineer in the System Verification Group to develop the next generation of hardware verification technology. This role focuses on evolving the SystemVerilog compiler to handle the complexities of AI and hyperscale chip designs. The successful...Principal
- Cadence is seeking a Senior Engineer for their System Verification Group to develop advanced compilers for AI and high-complexity chip designs. The role involves leading innovations in SystemVerilog language extensions and compiler architecture, ensuring that the tools...Principal
- A leading technology company is seeking a Senior Principal Software Engineer to join their Xcelium Compiler Team. This role focuses on implementing advanced compiler algorithms and collaborating on strategic architectural initiatives for simulation technologies. Candidates...Principal
$135k - $225k
...A Day in Your Life at MKS: As a Sr Principal Electrical Engineer at MKS you will partner with a talented, multidisciplinary team supplying precision... ..., and execution. Good understanding of manufacturing systems and documentation control, BOM structures, and ECO processes...PrincipalPermanent employmentVisa sponsorshipWork visa- ...Principal Electrical Engineer An industry-leading manufacturer of precision instrumentation is seeking a Senior Principal Electrical Engineer... ...experience designing precision analog electronics, embedded systems, and sensor technologies. You'll take ownership of electrical...PrincipalFull time
- Keurig Dr Pepper Inc. is seeking a Senior Principal Toxicologist in Burlington, Massachusetts. This role involves managing toxicology activities to support the development of safe food and beverages. You will work closely with various departments to ensure compliance and...Principal
- The MITRE Corporation in Bedford, Massachusetts, is seeking a Solution Lead Senior Principal (SLSP) to oversee 1-3 projects, driving them through the MITRE Innovation Lifecycle. The role requires strong project leadership and an entrepreneurial mindset to achieve disruptive...Principal
- Modern Technology Solutions, Inc. (MTSI) is looking for a Cyber Security - Information Systems Security Engineer (ISSE) based in Dayton, OH or Hanscom Air Force Base, MA. This role demands strong expertise in cybersecurity and the ability to integrate security into engineering...PrincipalFor contractors
$184.03k - $266.49k
Analog Devices, Inc. is seeking a Senior Principal Engineer, Systems Design/Architect in Wilmington, MA. The role involves defining products from concept to release, working with high-speed converters, and collaborating with customers to develop solutions for Industrial...Principal$132.46k - $179.21k
...industry, offering precision robotics, integrated automation systems, and contamination control solutions that empower chip... ...organization that is shaping the future of technology. Principal Electrical Engineer Job Description Position Summary The Principal...PrincipalWork at officeRemote workWorldwideFlexible hours$148k - $240k
...The Elevator Pitch Evolv is seeking a Principal Electrical Engineer, Analog & Sensor Systems to help shape the architecture and technical direction of next-generation sensor platforms deployed in complex, high-traffic, real-world environments. This is a hands...PrincipalFull timeLocal areaRemote workFlexible hours$134.4k - $201.6k
...Principal Electrical Engineer in Cardiac Ablation Solutions (CAS) At Medtronic, we bring bold ideas forward with speed and decisiveness to put... ...verification, and lifecycle support of complex electrical systems used in cardiac mapping and ablation therapies. This role...PrincipalH1bWork at officeLocal areaImmediate startFlexible hours$206k - $284k
...value, the team develops both engineering and operational prototypes... ...environments. The Role: As a Principal Algorithm & Signal... ...researchers in creating innovative system capability and collaborate with... ...PhD, MS, or BS in Electrical Engineering, Applied Mathematics...PrincipalFull timeFor subcontractorLocal areaImmediate start$134.4k - $201.6k
...cross-functional collaboration as we work together to engineer the extraordinary. The Principal Electrical Engineer in Cardiac Ablation Solutions (CAS) serves... ..., and lifecycle support of complex electrical systems used in cardiac mapping and ablation therapies. This...PrincipalH1bWork at officeLocal areaImmediate startFlexible hours- ...We are seeking an experienced and highly skilled System Safety Engineer to join our team. In this role, you will be responsible for leading... ...safety programs including analyzing explosive, mechanical, electrical, and software systems for hazards Developing system safety...Principal
- Analog Devices is looking for a Principal Analyst in Fab Supply Chain Planning to shape planning strategy in Wilmington, MA. This role requires... ...the fab environment. You will work closely with IT to ensure robust planning and execution systems. #J-18808-Ljbffr Analog DevicesPrincipal
$132.4k - $251.6k
...data analysis, including spectral processing and transfer function analysis, as well as data-driven simulations. Develop control systems and architectures to affect performance of physical systems. Support real-time implementation and evaluation of designs in realistic...PrincipalTemporary workFlexible hoursNight shift$175k - $200k
Senior Principal Software Engineer - Xcelium Compiler Team (R51299/ts) We are seeking a highly skilled and motivated Senior Principal Engineer to... ...Qualifications Experience with large-scale software systems and performance tuning Knowledge of simulation engines and...Principal- ...We are seeking an experienced and highly skilled Systems Engineer with an Electrical Engineering background to join our team. We believe people should love what they do – in this role, you will be responsible for various systems engineering efforts supporting the development...
Do you want to receive more vacancies?
Subscribe and receive similar vacancies to Principal Electrical Systems Engineer. Be the first to apply!
- general engineer Burlington, MA
- principal engineer Burlington, MA
- data center chief engineer Burlington, MA
- chief engineer Burlington, MA
- hotel chief engineer Burlington, MA
- senior civil engineer project manager Burlington, MA
- engineering director Burlington, MA
- principal developer Burlington, MA
- senior electrical designer Burlington, MA
- sr electrical engineer Burlington, MA

