Fullstack Software Engineer (Senior / Staff)

Fullstack Software Engineer (Senior / Staff)

Genesis Molecular AI is building a world-class software team to solve problems in drug discovery through machine learning, biophysical simulation, and computational chemistry. We are looking for engineers excited to help develop new medicines and play a critical role in building out our software platform.

You will

• Own and evolve the full-stack platform that computational chemists use daily, from data exploration and experiment management to real-time visualization, shipping AI-native workflows and modern interaction patterns that shorten the loop between hypothesis and insight
• Build and expand tools for visualizing molecules and proteins, analyzing ML models, and managing complex chemical workflows
• Partner with machine learning engineers and computational chemists to develop and productionize new computational methods for molecular property prediction
• Scale our data infrastructure to handle billions of datapoints and thousands of parallel deep learning and molecular dynamics jobs

You are

• A deep thinker who reasons from first principles, balances attention to detail with architectural thinking, and has an investigative curiosity to find the root cause of a problem
• Comfortable owning problems across the entire stack - frontend interfaces, backend services, data pipelines, and infrastructure
• Experienced shipping production code and driving projects end-to-end with minimal hand-holding
• Excited to work at the intersection of software engineering, drug discovery, and machine learning

What we offer

• The opportunity to work on high impact tools and products that are immediately deployed to accelerate the discovery of new medicines
• Strong technical coworkers in AI, software, and chemistry, who all have a powerful mix of intellectual curiosity and humility. The team reads and discusses 1-2 machine learning or chemistry papers every week to stay on top of the field and inspire new ideas
• Competitive salary and equity. Medical, dental, and vision insurance, and a 401(k) program

About Genesis Molecular AI

Genesis Molecular AI is pioneering foundation models for molecular AI to unlock a new era of drug design and development. The company's generative and predictive AI platform, GEMS (Genesis Exploration of Molecular Space), integrates AI and physics into industry-leading models to generate and optimize drug molecules, including the breakthrough generative diffusion model Pearl for structure prediction. Genesis has raised over $300 million from leading AI, tech and life science-focused investors, signed multiple AI-focused research collaborations with major pharma partners, and is deploying GEMS to advance an internal therapeutics pipeline for a variety of high-impact targets.


Genesis is headquartered in San Mateo, CA, with a fully integrated laboratory in San Diego. We are proud to be an inclusive workplace and an Equal Opportunity Employer.