Director, Medical Science Liaison, Midwest

Director, Medical Science Liaison (Sr. MSL /MSL) – US Midwest

For a complete understanding of this opportunity, and what will be required to be a successful applicant, read on.

Key Cities

Chicago, IL, Cleveland, OH and St. Louis, MO

Territory will include

North Dakota, South Dakota, Nebraska, Kansas, Minnesota, Iowa, Missouri, Wisconsin, Illinois, Indiana, Michigan, Ohio, Kentucky, Arkansas, Louisiana, Texas, Oklahoma

Damora Therapeutics is an innovative biotechnology company that aims to fundamentally redefine care for people with hematologic disorders. We are advancing a new generation of biologics to treat mutant calreticulin-driven myeloproliferative neoplasms, including essential thrombocythemia and myelofibrosis, where there is significant medical need for new disease-modifying treatments. With multiple programs with best-in-class potential entering clinical development in 2026, our goal is to rapidly bring forward optimized treatments with broad mutation coverage and exceptional convenience to dramatically improve patient outcomes.

This is a unique opportunity to join a science-driven company at a formative stage, where early clinical data will directly shape development strategy and drive long-term value. The right candidate will join a team with significant development experience, with the goal of quickly moving through dose escalation/expansion into pivotal trials.

The Role

As we enter this important growth stage, we are hiring a Director, Medical Science Liaison to cover the Midwest. They will be a foundational hire, reporting to the VP of Medical Affairs and joining a small established team to help build and shape our medical affairs function from the ground up. This is a chance to shape the function from day one, where early KOL and investigator scientific engagement and field insight will directly influence development strategy and long-term growth. You will work closely with executive leadership, operating both strategically and tactically to help guide clinical development, medical strategy, and future commercialization planning. This is an individual contributor role, offering the opportunity to make a deep impact through hands-on expertise rather than people management. Success in this position depends heavily on strong communication skills and the ability to build, deepen, and sustain trusted relationships with HCPs.

As a scientific face of the company, you will cultivate relationships with KOLs and investigators, support early clinical execution, and translate field insights into actionable strategy. At the same time, you will coordinate meetings, support advisory boards, implement tracking systems, and help build the processes needed to scale. Speed, ownership, and adaptability are essential — this role requires someone equally comfortable engaging in high-level scientific dialogue and managing the operational details that drive execution. The role will evolve as the pipeline progresses. Early on, there will be an emphasis on external scientific engagement. It is anticipated that the role will have an evolving mix of KOL engagement and assisting with internal development of the medical affairs function.

What You'll Do

Shape Scientific Engagement

• Identify, map, and develop relationships with KOLs, investigators, academic and community centers.
• Conduct compliant, high-quality scientific exchange around our investigational Phase I asset.
• Support site identification, feasibility assessments, and investigator outreach.
• Help develop medical strategy / scientific communications and represent the company at scientific congresses, advisory boards, and investigator meetings.

Support Early Clinical Development

• Partner closely with Clinical Development to support study execution.
• Gather structured and unstructured insights to inform protocol design and long-term strategy.
• Contribute to investigator materials and scientific content.
• Maintain consistent follow-up and communication with study sites.

Build Medical Affairs Operations Infrastructure

• Coordinate and schedule KOL meetings (virtual and in-person).
• Support logistics for advisory boards and scientific events.
• Track and document field interactions with accuracy and discipline.
• Help implement CRM tools, contact databases, and documentation systems.
• Assist in developing foundational SOPs and scalable medical processes.
• Comfort flexing into non-field responsibilities — e.g. publications, HEOR, medical education — as the role requires

Drive Insight & Strategy

• Synthesize field intelligence into actionable recommendations for leadership.
• Monitor the competitive and scientific landscape.
• Contribute to early medical strategy and long-range planning.
• Serve as a key voice in shaping the future medical affairs organization.

Ensure Compliance & Governance

• Maintain adherence to regulatory requirements and company policies.
• Document scientific exchanges with clarity and completeness.

What You'll Bring

• Advanced degree (PharmD, PhD, MD, or equivalent).
• 5+ years of MSL experience in hematology/oncology.
• Experience in a small or emerging biotech.
• Experience supporting clinical development and clinical operations (Phase I/II preferred).
• Strong understanding of clinical trial design and medical affairs functions.
• Ability to work independently in highly unstructured environments.
• Comfort moving between strategic dialogue, scientific exchange, and administrative execution.
• Excellent communication and presentation skills.
• Strong relationships with heme-onc KOLs
• Experience supporting advisory boards and investigator-initiated interactions.
• Willingness to travel (~50%+).

A plus if you have:

• Experience as an early or first medical hire.
• A track record of building processes without established infrastructure.

Compensation & Benefits

At Damora Therapeutics, we offer competitive compensation and thoughtfully designed total rewards aligned with industry benchmarks. We believe in rewarding impact and building meaningful ownership for our team.

Agency Policy

We are building our team intentionally and do not accept unsolicited resumes from recruiting or staffing agencies. Agencies should not submit candidates unless directly engaged by Damora's HR team and operating under a signed agreement. xhyhwjd Any resume submitted without prior authorization and a signed agreement will be considered property of Damora Therapeutics, and no referral or placement fees will be paid.