Cell Therapy Strategy and Commercial Executive Director
$267.91k - $401.87kAstraZeneca
Within the AstraZeneca Cell Therapy Enterprise, our ambition is to realize the full potential of cell therapy for people living with cancer, immune-mediated and rare diseases around the world. This unit has responsibility for the value chain from discovery through to late-stage development and commercialization. We are rapidly progressing a broad pipeline of cell therapies in collaboration with AstraZeneca’s Therapeutic Area Units.
The Strategy and Commercial Executive Director , Cell Therapy Strategy and Commercial (CTSC), is a high-impact leadership role accountable for shaping and driving the end-to-end strategy for a defined indication or disease area within Cell Therapy. You will lead global commercial and strategic initiatives within the Cell Therapy Enterprise CTU)—including business development and competitive intelligence—partnering with Therapeutic Areas on clinical strategy, collaborating with in-market commercial and medical affairs on launch readiness, and aligning with global pricing and brand teams. Working cross-functionally with senior leaders, you will define early asset, disease, and portfolio strategies through PH3IDs. Reporting to the VP, Cell Therapy Strategy and Commercial, you will be a key architect of the company’s Cell Therapy strategy and lead cross-functional execution.
Key Accountabilities:
Deliver end-to-end Strategy, including:
- Clear understanding and prioritization of current and future unmet needs
- Indication-level strategic vision for both near-term and long-term
- Integrated clinical strategy across all cell therapy platforms within the same indication
- Work with global Clinical and ClinOps within respective TAs to develop comprehensive development strategy
- Competitive early pipeline / long-term portfolio and life cycle management
- Above-asset initiatives (e.g., Translational Medicine, Precision Medicine, Data Sciences)
Own insights generation for R&D and commercial activities
- Oversees and guides development and integration of industry-leading competitive intelligence, customer insight, market intelligence and analytics helping the organization to frame business problems and opportunities
- Shape future-proofed strategies and deliver sustainably differentiated brands/early assets, business development opportunities and TA strategies
- Responsible for the robustness and transparency of the forecasts for PH3IDs
- Bring an intelligence-driven perspective to strategic recommendations by synthesizing insights from diverse sources and publicly available information at the brand and Therapeutic Area level for internal and external communication
- Responsible for creating and curating evidence bank from real world data sources to support the PH3ID forecasts created within the team
Lead global commercial cell therapy within indication
- Build the referral capabilities between specific disease areas and the Cell Therapy delivery centers
- Partners closely across different areas of Cell Therapy, Global Commercial, in-market commercial and medical affairs teams to ensure execution of global strategy
- Lead and collaborate with cross-functional teams (e.g., GPTs, Clinical Development, Discovery, BD, Lifecycle and Pipeline, Competitive Intelligence) to develop disease area strategy content
- Provide strategic counselling to Global Clinical Strategy Head (GCSH), Global Commercial and Medical Affairs leadership, and other senior leaders
Basic Qualifications:
- BA/BS and 10 years of experience in life sciences or consulting firm with focus in life science programs
- OR MS/MBA and 8+ years of experience in life sciences or consulting firm with focus in life science programs
- OR PhD or MD and 5+ of experience in life sciences or consulting firm with focus in life science programs
- Ability to interact and communicate effectively with senior executive teams.
- Demonstrated ability to lead and influence experienced professionals.
- Ability to think critically, creatively and to anticipate and solve problems.
- Ability to navigate and be successful in a fast-paced, highly-matrixed work environment
Preferred Qualifications:
- Strong analytical and communication skills
- Strong business acumen and strategic thinking skills preferably demonstrated in a pharma related environment.
- Effective interpersonal and relationship management skills with consultative approach and ability to interact and build trust
- Operational effectiveness, highly organized process with follow through
- Strong initiative to understand our core business goals and establish processes or programs to set direction, generate alignment and push forward
- Financial background and understanding of forecasts, budgets, financial activities and tools
- Resourceful, motivated, influential and proactive; able to prioritize in a fast-growing organization
- Experience in strategic planning processes and tools
- Scientific background
- Understanding of the pharmaceutical business (including R&D)
- Experience in translating business needs into a coordinated plan from cross-functional senior leadership team
- Ability to develop creative and simple solutions to complex problems
In-Office Working Requirements
When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That’s why we work, on average, a minimum of three days per week from the office. But that doesn’t mean we’re not flexible. This role can be based in Gaithersburg MD, Boston MA, South San Francisco CA, New York NY.
The annual base pay for this position ranges from $267,914 to $401,870. Our positions offer eligibility for various incentives—an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans.
Date Posted
24-Sep-2026Closing Date
Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.
$271.2k - $406.8k
...lethality to discover and develop therapies that take aim at critical targets in... ...contribution to the ability of cancer cells to evade immune cell killing.The... ...of Boston, Massachusetts.SummaryThe Executive Director, Commercial Strategy & Execution will lead strategic...SuggestedWork experience placement$276k - $414k
...Job Title: Executive Director, Regulatory Affairs Strategy - Cell Therapy Available locations: NYC, NY Gaithersburg, MD Boston, MA South San... .... You will work across discovery through commercialization, bringing clarity and pace to decision-making and...SuggestedHourly payFull timeTemporary workWork at officeWorldwideFlexible hours3 days per week$268.2k - $402.2k
Job DescriptionGeneral Summary:The Executive Director, Regulatory Strategy will serve as a seasoned regulatory leader with expert technical and tactical... ...regulatory strategies for product development and commercialization of programs within the T1D portfolio. This position...SuggestedFull timeSummer workLocal areaRemote workFlexible hours2 days per week$244.8k - $367.2k
...DescriptionPosition Summary:The Executive Director serves as a strategic... ...and executing the Cell & Genetic Therapies (CGT) Quality vision, operating... ..., and organizational strategy. The role is accountable... ...development through commercialization while building scalable,...SuggestedFull timeSummer workFlexible hours$235k - $335k
...provide a new generation of convenient, highly effective therapies for patients with these conditions. Founded in 2016, Kymera... ....How you’ll make an impact:Kymera is seeking a Senior/Executive Director, AI Strategy & Applications to serve as the company's first dedicated...Suggested$185k - $315k
...to create a thriving ecosystem that delivers accessible, high-quality, and sustainable healthcare for all.The Executive Director, Specialty Commercial Strategy will lead the commercial strategy and business performance of athenahealth’s specialty growth initiative. This...Full timeTemporary workWork at office$251.2k - $376.8k
...discover and develop therapies that take aim at critical... ...ability of cancer cells to evade immune cell... ...finance leader to serve as Executive Director, FP&A. Reporting... ...planning & analysis strategy and execution, partnering... ...early-stage commercial finance support and analysis...$315.2k
...lethality to discover and develop therapies that take aim at critical... ...to the ability of cancer cells to evade immune cell killing... ...oncology leader to serve as Executive Director, Clinical Development. Reporting... ...the clinical development strategy for an early-stage program....- ...world's first CRISPR-based therapy, approved for eligible patients with sickle cell disease and transfusion... ...Development, the Executive Director will provide clinical development strategy, mentoring of clinical... ...management, statistics, safety, commercial, and regulatory affairs...Remote work
- ## Director, Clinical DevelopmentApplyremote... ...first CRISPR-based therapy, approved for eligible... ...with sickle cell disease and transfusion... ...trial design and execution, and preparation/... ..., safety, commercial, and regulatory affairs... ...study and program strategy* Develop scientific...Remote work
$302.01k - $390.83k
...cancer - working relentlessly to develop therapies that help improve lives and to ensure... ...to the Head of Biometrics, the Executive Director of Biostatistics for Medical Affairs will... ...according to priorities and business strategies.Negotiates project timelines across programs...Full timeTemporary workFor contractorsLocal area- ...development of groundbreaking therapies. Our mission is to be... ...possible.The Commercial Product Manager is responsible... ...& services by executing commercial launches as defined by Product Strategy, and working with our... ...field preferred (e.g. cell biology, molecular biology...Full timeRemote workWork from homeFlexible hours
$302.01k - $390.83k
...Executive Director Of Biostatistics For Medical Affairs At Gilead, we're creating a healthier... ...– working relentlessly to develop therapies that help improve lives and to ensure... ...according to priorities and business strategies. Negotiates project timelines across...Temporary work$265.6k - $398.4k
Job DescriptionGeneral SummaryThe Executive Director, Commercial Analytics leads the Commercial Analytics Center of Excellence within US Commercial... ...forecasting excellence, including best practices, vendor strategy, and innovation.Provide executive oversight of short- and...Full timeSummer workRemote workFlexible hours2 days per week$238k - $374k
...innovation and delivers transformative therapies to patients. By focusing R&D efforts... ...changing therapies to patients worldwide.As Executive Director, Global Regulatory Affairs CMC Devices... ...innovative and robust regulatory strategies for medical devices and drug-device combination...Minimum wageTemporary workWork at officeLocal areaRemote workWorldwide$313.2k - $391.5k
...3, we launched our fourth therapy and the first ever gene therapy... ...of the Role The Executive Medical Director, SERM will provide leadership... ...Affairs, Quality Assurance, and Commercial.The Opportunity to Make a... ...product risk management strategy and facilitates production...Full time$328k
...DescriptionGeneral Summary:The Executive Medical Director, Global Medical Lead (GML)... ...for the global medical strategy and implementation and... ...strategic alignment with commercial and other cross-functional... ...literature, etc.) for pipeline therapies and marketed medicines...Full timeSummer workRemote workFlexible hours2 days per week$286.9k
...empower you to shine? Join us as an Executive Medical Director, Oncology Clinical Sciences in our... ...ongoing review and agreement of the therapy area strategy and associated documents formulated... ...strategy and to support of product commercial efforts Contributing to the...Minimum wageTemporary workWork at officeLocal areaNight shift$228k - $313.5k
...Position Summary : We are seeking an Executive Director, CMC (Chemistry, Manufacturing &... ...record of driving portfolio-level CMC strategy and execution across multiple emerging... ...modalities incl. nucleic acids, cell or gene therapies Demonstrated track record of filing...Contract work$327.1k - $399.9k
...tools to advance genome editing therapies. This role will oversee the planning, execution, and delivery of projects to support... .... This role will develop strategy, implement, and lead state-of-the... ...technologies: Including NGS, ddPCR, single-cell genomics, and spatial...Full timeLocal area$332.8k
...to discover and develop therapies that take aim at... ...the ability of cancer cells to evade immune cell killing... ...Development, this highly visible executive will lead the clinical development strategy from early stage... ...a team of Medical Directors and Clinical Scientists...$181.8k - $272.6k
Job DescriptionGeneral Summary:The Director, Supply Chain Management, Cell and Gene Therapy will lead the global commercial supply chain planning, strategy and operations for Vertex’s Type 1 Diabetes (T1D) program. The strategy includes long term capacity build plans...Full timeSummer workRemote workFlexible hours2 days per week- Flagship Pioneering's Pioneering Medicines in Cambridge, MA seeks an Executive Director, CMC to lead portfolio-level CMC strategy and execution across multiple modalities. This senior role combines strategic oversight with hands-on management. The position oversees Drug...
$278.57k - $417.85k
Executive Director, Biometrics - CVRM The Opportunity Are you an accomplished biometrics leader with... ...medicines? Would you like to shape the strategy and execution of clinical development... ...’s most important and fastest-growing Therapy Areas? AsExecutive Director, Biometrics...Temporary workInterim roleWork at office3 days per week$251.61k - $377.42k
...capabilities to drive a successful strategy in accelerating the development of cellular therapies for patients with immune-... ...the discovery, development and commercialization of prescription medicines for... ...functional Global Product Team to execute and deliver the pre-clinical...Hourly payFull timeTemporary work$230k - $330k
...Overview Rhythm is a global, commercial-stage biopharmaceutical... ...indications. As an Executive Medical Director, this physician will serve... ...ensuring alignment of clinical strategy across studies,... ...patients and developing novel therapies for other rare neuroendocrine...Full timeWork at office$246k - $332k
...Department: 102600 Corp Strategy & Development Location:... ...and deliver life-changing therapies to people living with rare... ...Position Summary The Executive Director, Corporate Development will... ...Clinical Development, Regulatory, Commercial, Finance, Legal, Intellectual...Temporary workRemote workShift work$243k - $373k
...KGaA, Darmstadt, Germany, is a commercial-stage biopharmaceutical... ...for . Your Role: The Executive Director, U.S. Brand Lead of NF1-PN Marketing... ...for leading the brand strategy, execution and measurement to... ..., AIDS/HIV status, sickle cell or hemoglobin C trait, genetic...Temporary workWork at officeLocal area3 days per week- The Lincoln Institute of Land Policy, based in Cambridge, MA, seeks an Executive Director of Land and Communities to lead strategy, research, and external engagement. You will oversee program content, ensure high-quality research outputs, and advance fundraising with a...
- Role Executive Director, CMC (Chemistry, Manufacturing & Controls) at Flagship Pioneering's Pioneering... ..., leading portfolio-level CMC strategy and execution across multiple emerging... ...modalities like nucleic acids or gene therapies track record in filing regulatory dossiers...
Do you want to receive more vacancies?
Subscribe and receive similar vacancies to Cell Therapy Strategy and Commercial Executive Director. Be the first to apply!
- commercial executive Cambridge, MA
- chief commercial officer Cambridge, MA
- commercial manager Cambridge, MA
- commercial sales manager Cambridge, MA
- commercial director Cambridge, MA
- sales excellence & strategy manager Cambridge, MA
- strategic planning director Cambridge, MA
- strategic director Cambridge, MA
- director corporate strategy Cambridge, MA
- senior strategic account manager Cambridge, MA


