Associate Scientist/Scientist - Nanoparticle Formulation & Process Development

Design, prepare, and optimize nanoparticle formulations, including lipid-based and polymeric systems. Perform formulation screening studies to evaluate performance across key parameters (e.g., composition, ratios, process conditions). Operate and optimize nanoparticle manufacturing platforms, with a preference for microfluidic mixing technologies; experience with impinging jet mixing or other rapid-mixing methods is a plus. Support downstream process development activities, including buffer exchange, dialysis, tangential flow filtration (TFF), concentration, sterile filtration, and fill/finish preparation. Contribute to the design and execution of bioconjugation strategies, including conjugation of antibodies, peptides, ligands, or polymers to nanoparticles or their components. Analyze and interpret experimental data, maintain detailed records, and communicate findings to internal stakeholders. Collaborate cross-functionally with R&D, analytical, and manufacturing teams to advance programs from early development through scale-up. Requirements: Bachelor’s or Master’s degree in Chemistry, Chemical Engineering, Bioengineering, or a related field. Must have 3+ years experience with nanoparticle formulation development (lipid nanoparticles, polymeric nanoparticles, or similar systems). Working knowledge of nanoparticle characterization techniques (e.g., DLS for size/PDI, encapsulation assays, stability testing). Experience supporting downstream processing workflows such as TFF, dialysis, or sterile filtration. Understanding of bioconjugation techniques; hands‑on experience strongly preferred. #J-18808-Ljbffr Commonwealth Sciences, Inc.