Principal Software Engineering Lead (eCOA) - Evinova
$165.66k - $217.42kAstraZeneca
WHY JOIN US?
Evinova is a health-tech business, accelerating the delivery of better health outcomes by propelling the life sciences sector forward in digital health, from the inside. Through our application of science-based expertise, evidence-led rigour, and human insight, our digital solutions are deliberately designed so that everyone can reach better health outcomes together. Evinova is a health-tech business within the AstraZeneca Group. Digital health, the point at which healthcare, technology, data and analytics converge, is the subject of phenomenal promise, with the World Health Organisation believing it has the potential to improve health for everyone. At AstraZeneca, we’ve been working hard to make this a reality, with the years of experience we have accumulated enabling us to now embed digital health at scale across R&D. To achieve our goal of improving patient experience and outcomes AstraZeneca has Digital Health as one of the top 4 strategic priorities for the company, details on digital health strategy can be found here. Oncology is the largest therapeutic area within AstraZeneca and second highest cause of death globally, with AstraZeneca’s ambition to eliminate cancer as a cause of death. Recognizing the importance of individualized flexibility, our ways of working allow employees to balance personal and work commitments while ensuring we continue to create a strong culture of collaboration and teamwork by engaging face‑to‑face in our offices 3 days a week. Our head office is purposely designed with collaboration in mind, providing space where teams can come together to strategise, brainstorm and connect on key projects. About Our Engineering Organization Our Product Engineering organization consists of cross‑functional squads with the people and skills needed to deliver innovative digital products to patients and healthcare providers in clinical trials worldwide. We ship on quarterly program increments using agile methodology. We are proud to have one of the strongest software development teams in the health tech space, with deep technical and domain skills. This is a place where you build real things, solve hard problems, and grow alongside engineers who care deeply about their craft and its purpose. About the Role This is not a traditional management role. We are looking for a hands‑on engineering leader who writes and reviews code, makes architecture decisions in pull requests, and leads by building alongside their team. You will own the technical direction and delivery of our eCOA product area while leading a multi‑squad engineering organization. You will spend a significant portion of your time in the codebase: reviewing pull requests, pairing with engineers on complex problems, evaluating AI‑assisted development workflows, and ensuring our architecture scales. The remainder of your time is spent on team development, cross‑functional collaboration, and technical strategy. We expect you to be the strongest technical voice in the room on your product area, someone who can credibly challenge an architectural decision, spot issues in a code review, and prototype solutions to unblock the team. Key Responsibilities Hands‑On Technical Leadership (50%+ of your time) Regularly review pull requests, provide substantive code‑level feedback, and enforce quality standards across squads. Make and own architectural decisions for the eCOA platform, including API design, data models, service boundaries, and infrastructure choices. Write production code, particularly for complex or foundational components where your expertise accelerates the team. Pair with engineers on difficult problems and use these sessions as coaching opportunities. Drive adoption of AI‑assisted development tools and workflows, establishing team conventions for AI code generation, prompt engineering, and automated testing. Define and enforce technical standards: testing strategy, CI/CD pipeline health, observability, and deployment practices. AI‑Native Engineering Culture Embed AI tools (coding assistants, agentic workflows, automated code review) into the team’s daily development process as a force multiplier, not an experiment. Evaluate and integrate AI capabilities into the eCOA product itself, including intelligent data capture, adaptive questionnaire logic, and patient experience personalization. Champion a culture where engineers own AI‑generated output with the same rigor as hand‑written code: thorough review, testing, and accountability. Stay current with rapid advances in AI‑assisted development and translate those into practical team‑level improvements. Team Leadership & Development Lead, mentor, and grow a multi‑squad engineering organization. Develop squad leads into strong technical leaders in their own right. Set a high technical bar in hiring: personally conduct technical interviews and assess candidates’ ability to build, not just describe. Foster a culture of continuous improvement, psychological safety, and intellectual honesty about technical debt and tradeoffs. Manage performance with clear, measurable expectations rooted in engineering output and quality, not just process compliance. Product & Delivery Partner with Product Owners to translate clinical requirements into sound technical plans, ensuring feasibility, scalability, and regulatory compliance. Drive execution against quarterly program increments with predictable, high‑quality delivery. Collaborate across the Unified Trial Solution engineering organization to ensure architectural coherence and shared platform leverage. Minimum Qualifications Bachelor’s or Master’s degree in Computer Science, Engineering, or equivalent demonstrated through professional experience 8+ years of professional software engineering experience, with a strong track record of building and shipping production systems. 3+ years leading engineering teams (squads, chapters, or similar) while remaining hands‑on with code. Deep proficiency in at least one of our core stacks: React/React Native (frontend), Node.js/Java (backend), AWS cloud services. Demonstrated ability to make sound architectural decisions across frontend, backend, and infrastructure. Practical, daily experience using AI‑assisted development tools (GitHub Copilot, Claude, Cursor, or similar) in your own coding workflow. Strong understanding of agile delivery frameworks (Scrum, Kanban, SAFe) applied in practice, not just theory. Desired Qualifications Experience building or deploying AI/ML features in production applications, including agentic AI systems or LLM integrations. Experience developing and delivering electronic Clinical Outcome Assessments (eCOA) or patient‑facing clinical trial software. Familiarity with GxP, SaMD validation, or regulated software development processes. Experience with remote patient monitoring (RPM) solutions including patient‑reported data and clinician‑facing visualizations. Contributions to open‑source projects or a visible track record of technical thought leadership (blog posts, conference talks, published architectural decisions). Clinical research domain experience. What This Role Is Not A pure people‑management position where you are removed from the codebase. If you haven’t written or reviewed code in the past month, this role is not the right fit. A project management role. We have Product Owners and delivery support for process coordination. You own the technical how, not the project timeline. A checkbox exercise in AI adoption. We need someone who has genuinely transformed their own development workflow with AI tools and can credibly lead others to do the same.SO, WHAT’S NEXT?
To be considered for this exciting opportunity, please complete the full application on our website at your earliest convenience – it is the only way that our Recruiter and Hiring Manager can know that you feel well qualified for this opportunity. If you know someone who would be a great fit, please share this posting with them. Where can I find out more? Learn more about Evinova Our Social Media, Follow AstraZeneca on LinkedIn Follow AstraZeneca on Facebook Follow AstraZeneca on Instagram Our US Footprint: Powering Scientific Innovation - YouTube Are you interested in working at Evinova, apply today! AstraZeneca is an equal opportunity employer that is committed to diversity and inclusion and providing a workplace that is free from discrimination. AstraZeneca is committed to accommodating persons with disabilities. Such accommodation is available on request in respect of all aspects of the recruitment, assessment and selection process and may be requested by emailing View email address on click.appcast.io. #LI-Hybrid The annual base pay for this position ranges from $165,656.80 - $217,424.55 USD. Base pay offered may vary depending on multiple individualized factors, including market location, job‑related knowledge, skills, and experience. In addition, our positions offer a short‑term incentive bonus opportunity; eligibility to participate in our equity‑based long‑term incentive program. Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at‑will position” and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors. Date Posted 08-Jun-2026 Closing Date 29-Jun-2026 Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form. #J-18808-Ljbffr AstraZenecaVacancy posted 1 day ago
Similar jobs that could be interesting for youBased on the Principal Software Engineering Lead (eCOA) - Evinova in Gaithersburg, MD vacancy
$131.3k - $237.35k
...secure cloud operations for the future. We’re seeking a Principal Engineer / Technical Lead to support the Compartmented Enterprise Services Office... ...pipelines (structured/unstructured) Experience with software development languages/environments such as: JavaScript....SuggestedTemporary workWork at officeLocal areaImmediate start$134.87k - $202.3k
...Title: Generative AI Cloud Operations Engineer - Evinova Location: Gaithersburg, MD At AstraZeneca... ...Group. Evinova delivers market‑leading digital health solutions that are science... ...CDK for python and/or TypeScript Strong software engineering abilities in Python/TypeScript...SuggestedHourly payTemporary workWork at officeRelocation3 days per week$87.1k - $157.45k
...Description We are seeking a Lead Software Developer who will be a member of a dynamic team Air Traffic Management program - SkyLine-X™... ...and translate them into robust software designs using sound engineering principles Lead implementation of moderately complex features...SuggestedLocal areaImmediate start$130.8k - $203.07k
Principal Software Engineer - On-site Location: Germantown, MD, US, 20876 Job ID: 114271 DRS RADA Technologies, a subsidiary of Leonardo DRS, is... ...Python, Linux, React, Node, and other languages. Ability to lead a technical group independently. Open to occasional travel...SuggestedContract workFor contractorsWork experience placementLocal areaFlexible hours$131.3k - $237.35k
Description We are seeking a Principal Software Developer who will be a member of a dynamic team... ...principal technical authority for software engineering across one or more programs,... ...design, and long-term technical strategy Lead the design and development of complex,...SuggestedLocal areaImmediate start$143.4k - $215k
...OpenText enterprise content management (ECM) software provides Content Services to help... ...What the role offers As a Lead Software Developer, you will: Design... .... ~5+ years of experience in software engineering (or equivalent experience). ~ Familiarity...$87.1k - $157.45k
...Description Leidos is looking for a Software Engineer focusing on System Management supporting our Federal Aviation Administration (FAA) Terminal Flight Data Manager (TFDM) program. The successful candidate will play a crucial role in ensuring the seamless integration...Work at officeLocal areaImmediate startHome office2 days per week3 days per week$87.1k - $157.45k
...Description Leidos is seeking a Lead Software Developer , who will be a member of a dynamic team in Gaithersburg, MD, working on the... ..., and implement next-generation application using software engineering best practices in the latest technologies: Infrastructure-...Local areaImmediate start$130.8k - $203.07k
Leonardo DRS in Germantown, MD is hiring a Principal Software Engineer responsible for driving technical vision and architecting solutions across the product ecosystem. The ideal candidate will have a Master’s degree and 8 years of experience, with deep expertise in C/C++...$103.71k - $138.28k
...and hands-on position requiring the selected candidate to both lead and participate in multiple team environments and to provide independent... ...knowledge and experience in system architecture and engineering disciplines. Specific technical knowledge of enterprise level networking...Full timeTemporary workRemote work$87.1k - $157.45k
Description Leidos is seeking a Lead AISoftware Developer to join the Air Traffic Business... .... As a member of a Scaled Agile software development organization, you will contribute... ...a combination of traditional systems engineering and AI‑augmented software development practices...Contract workWork from home$134.26k
...Unit: IND Job Description: As a Lead Substation Protection & Control (P&C), you... ...and control systems, mentor junior engineers, and collaborate directly with clients and... ...assisted design and drafting (CADD) 3D and 4D software and practices. Expert knowledge of...Full timeH1bLocal area$87.1k - $157.45k
...Description Leidos is seeking a Lead AI Software Developer to join the Air Traffic Business Area within the Homeland Sector, supporting... ...solutions independently while working closely with systems engineering, product delivery, and DevSecOps teams. The primary focus...Contract workLocal areaImmediate startWork from home$87.1k - $157.45k
...Description Leidos is seeking a Lead DevSecOPS Soft ware Developer to join the... ...architecture. As a member of a Scaled Agile software development organization, you will... ...using a combination of traditional systems engineering and AI-augmented software development practices...Local areaImmediate startWork from home$87.1k - $157.45k
...is seeking a Systems Integration & Test Engineer who will be a member of a dynamic team on... ...interface checkouts • Work with team lead to provide guidance to fellow test team members... ...conjunction with System Engineering and Software in regard to developing solutions •...Local areaImmediate startRemote work- AstraZeneca GmbH, located in Gaithersburg, Maryland, is seeking a hands-on engineering leader with expertise in software engineering to lead their eCOA product area. The role emphasizes technical leadership, collaboration, and innovative problem-solving. The successful...
- A leading scientific organization is seeking a hands-on Team Lead for their software engineering team in Rockville, Maryland. This role requires a technical powerhouse who can balance hands-on coding with effective team mentorship and tactical management. The ideal candidate...
$40 per hour
Sunstall Inc. is seeking a Building Engineer in Gaithersburg, MD, offering $40/hr. This role is responsible for the maintenance and repair of mechanical and electrical equipment in commercial buildings. Ideal candidates possess a minimum of 5 years of relevant experience...Afternoon shift- A technology solutions company is seeking a Lead Software Engineer who will manage build dependencies and lead a dynamic team working on software to improve aircraft traffic efficiency. The role involves running Scrum meetings, managing cross-team dependencies, and automating...
- Lead Software Engineer Leidos is seeking a Lead Software Engineer who will be the Build Lead for a dynamic team working on the development of software that improves aircraft runway and terminal congestion. Nationwide congestion is increasing, and the need for efficient...
- X-Energy, LLC in Rockville, Maryland is seeking a professional to support the acquisition and development of engineering analysis software for nuclear power reactors. This role involves responsibility for documentation, software maintenance, and collaboration with project...
- A leading defense contractor located in Gaithersburg, Maryland, is seeking an experienced Cross Domain Implementation Engineer Lead. You will design, deploy, and maintain secure data transfer solutions while leading a technical team. Ideal candidates will have at least...For contractors
$140k - $165k
...Compensation Based on Experience. Sr. Software Engineer $140000 - $165000 per year | Gaithersburg, MD | On-Site | Permanent A bit about us: We are a technology consulting and cloud solutions organization specializing in the design, development, and implementation of highly...Permanent employmentLocal area$70k - $120k
...Developer CERTIFY Global is an innovative software organization that provides a seamless patient experience via biometric authentication... ...and maximize the effectiveness of available technology. Principal Duties and Responsibilities: Develop, Test and Debug...Work at officeMonday to Friday- ...GENERAL DUTIES: Full Stack Engineer for the Maru Program on the Joint Analytic Workspace System (JAWS) Modernization team Resolve... ...by the team product owner Engage in the complete software development lifecycle, operating within well-defined parameters...
- ...Developer CERTIFY Global is an innovative software organization that provides a seamless patient experience via biometric authentication... ...industry. Interns will have the ability to engage in Engineering and Product Support, while collaborating with key stakeholders...Internship
- ...Software Engineer Reinventing Geospatial (RGi) is a leading expert in geospatial solutions for Defense, Intelligence, and Federal clients. We enhance situational awareness for soldiers and analysts by integrating software development with geospatial intelligence. Our...Immediate start
$107.9k - $195.05k
Via Logic LLC is seeking a Systems Engineer to lead the Concurrent Engineering team for air traffic control systems in Maryland. The role involves modernizing equipment, streamlining scheduling, and managing team collaboration with the FAA for the Terminal Flight Data...- ...Software Engineer Position The TFDM Program is an FAA NextGen program. TFDM capabilities are being incrementally deployed to provide efficiencies in the airport surface and terminal airspace by providing new integrated surface traffic control and management capabilities...
$69.55k - $125.73k
...Description We are seeking a Software Developer who will be a member of a dynamic team Air Traffic Management program - SkyLine-X™ SkyLine... ...and apply appropriate design techniques and software engineering principles to develop code that is modifiable, efficient, reliable...Local areaImmediate start
Do you want to receive more vacancies?
Subscribe and receive similar vacancies to Principal Software Engineering Lead (eCOA) - Evinova. Be the first to apply!
Related searches
- lead operating engineer Gaithersburg, MD
- lead engineer Gaithersburg, MD
- senior principal cloud computing engineer Gaithersburg, MD
- senior principal scientist Gaithersburg, MD
- principal Gaithersburg, MD
- software support Gaithersburg, MD
- software sales Gaithersburg, MD
- embedded software Gaithersburg, MD
- remote software sales Gaithersburg, MD
- software technical support Gaithersburg, MD



