Postdoctoral Associate | Laboratory of Genetically Encoded Small Molecules

Postdoctoral AssociateResearchers in the Laboratory of Genetically Encoded Small Molecules are working on projects related to the human microbiome, bacterial small molecules, and host-microbial interactions. The lab's research is focused on identifying bacterial genes, pathways, and molecules that influence host-cellular functions and developing these host-microbial interactions into novel treatments for human disease. To this end, we focus on three major areas of research: high throughput screening of bacterial metabolites and genes to identify effector functions, mouse models of inflammatory and metabolic diseases, and in vivo validation of bacterial metabolites and genes in human cohorts.The Postdoctoral Associate will use methods from molecular biology, organic chemistry, and microbiology to access bioactive natural products and their respective biosynthetic gene clusters from the soil. Will be responsible for using a range of techniques, including molecular biology, tissue culture, animal work (mouse), and chemistry.Responsibilities include:Design and execute independent and collaborative research projects.Maintain strong organizational practices, attention to detail, and accurate researchCommunicate effectively and work both independently and collaborativelyEngage in scientific writing and dissemination activities, including opportunities to lead first-authored manuscripts and contribute to collaborative publications and literature reviewsPerform related duties & responsibilities as assigned/requestedQualificationsREQUIRED QUALIFICATIONS:PhD in chemistry, biochemistry, microbiology, biology, or a related fieldAbility to independently conduct untargeted metabolomics studies and/or phylogenetic analyses of microbial communities in microbiome samples.Strong organization skills, attention to detail, and ability to maintain accurate recordsExcellent communication skills and the ability to work both independently and as part of a collaborative team in a fast-paced research environmentPREFERRED QUALIFICATIONS:Experience in multi-step natural product synthesis, medicinal chemistry, small molecule library development, compound characterization, and/or structure activity relationship optimizationExperience in preparative and analytical chromatography and structural analysis of organic moleculesExperience in peptide synthesisExperience with metabolite discovery and characterizationThe Rockefeller University is an equal opportunity employer – veterans/individuals with disabilities. Qualified applicants will receive consideration for employment without regard to characteristics protected by applicable local, state or federal law, including but not limited to disability and protected veteran status.The salary of the finalist selected for this role will be set based on various factors, including but not limited to organizational budgets, qualifications, experience, education, licenses, specialty, and training. The hiring range provided represents The Rockefeller University's good faith and reasonable estimate of the range of possible compensation at the time of posting.Compensation Range: MinUSD $72,100.00/Yr. Compensation Range: MaxUSD $72,100.00/Yr. Rockefeller University