Research Scientist

Bachem is a leading, innovation-driven company specializing in the development and manufacture of peptides and oligonucleotides. With over 50 years of experience and expertise Bachem provides products for research, clinical development and commercial application to pharmaceutical and biotechnology companies worldwide and offers a comprehensive range of services. Bachem operates internationally with headquarters in Switzerland and locations in Europe, the US and Asia. The company is listed on the SIX Swiss Exchange. For further information, see A brief overview The Scientist / Sr. Scientist within the Peptide Competence Center (PCC) leads peptide process development and life cycle management for Bachem Americas while strengthening expertise in manufacturing, NCE development, and collaboration with global Bachem sites. This role supports customer-driven projects, drives innovation in peptide synthesis and purification, and implements technologies to enhance GMP manufacturing efficiency and cost-effectiveness. Responsibilities also include optimizing automated development equipment and sharing advanced peptide chemistry knowledge with production and development teams. What you will do Execute peptide API projects, including research, validation, troubleshooting, and process optimization. Take ownership of assigned tasks, ensuring timely, high-quality, and cost-effective execution. Provide regular updates and communicate project progress to stakeholders. Manage and maintain production equipment and infrastructure, including preventive maintenance. Plan and allocate resources to ensure efficient execution of service orders and optimal use of personnel and equipment. Identify and implement improvements in safety, regulatory compliance, and process efficiency. Independently develop, optimize, and troubleshoot peptide chemistry processes. Contribute to broader business process improvements to enhance quality, efficiency, and speed. Ensure compliance with applicable directives, regulations, and internal procedures. Evaluate, recommend, and implement new technologies and equipment for peptide synthesis and purification. Conduct research in peptide chemistry, including solid-phase peptide synthesis (SPPS), purification, and isolation. Train and coach team members in NCE life cycle management approaches in accordance with the company's CMC concept and in advanced peptide chemistry-related topics. Qualifications PhD in Organic Chemistry or Biochemistry (preferred) OR Master's degree in Organic Chemistry or Biochemistry with at least 3 years’ experience 3 years+ of hands‑on experience in small-scale/large-scale chemical synthesis and their relevant purification such as RP-HPLC and ion exchange HPLC. Strong hands‑on solution and solid‑phase synthesis experience and analytical skills with ability to solve chemical and process problems. Experience in different analytical and preparative HPLC techniques specifically RP-HPLC and Ion exchange Broad understanding of new trends and emerging technologies in the field of Organic Chemistry, specifically peptide chemistry Ability to work independently to design new experiments to probe a process to generate fundamental mechanistic understanding of a chemical reaction, and ability to interpret results obtained. In depth understanding of MS spectroscopy as applied to peptide analysis Understanding of general NMR principle (1H-NMR, 13C-NMR, 2D-NMR) and NMR data interpretation Excellent written and oral communication skills. Ability to provide periodic written updates of technical findings to senior management, and present research findings to senior executives. Support patent filings with proper documentation and interactions with patent counsels. Basic computer knowledge, including Microsoft Word, Excel and PowerPoint Self-starter, ability to effectively organize, multitask, and work in a fast-paced, deadline driven work environment. High competence in new trends and emerging technologies in the field of peptide chemistry and Organic Chemistry Base Annual Salary Range Scientist: $94,800 - $130,350 Sr. Scientist: $115,767 - $159,180 Placement of new hires in these wage ranges is based on several factors including education, skill sets, experience, and training. Total Rewards We offer all Team Members a total rewards package including competitive pay, annual performance bonus, a generous benefit package with comprehensive Medical/Dental/Vision coverage, 401(k) plan with employer contribution, and paid vacation, personal and sick days. Corporate Social Responsibility Bachem takes responsibility for future generations by careful handling of resources and avoiding environmental risks. We continually improve our ecological performance and develop and implement new approaches for enhancing employees’ environmental awareness. EcoVadis has awarded Bachem Gold Medal status in their assessment of Bachem. Bachem Americas is an Equal Opportunity Employer As an equal opportunity employer, we celebrate the diversity of our team and are committed to building an inclusive workplace where individuals are hired and advanced based on merit, skills, and qualifications. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, sexual orientation, national origin, genetics, disability, age, veteran status, or other legally protected status. At Bachem, you’ll find a diverse, multicultural team. The (a) in the job title stands for all. We welcome applications from all candidates. What matters are your skills and motivation—regardless of age, gender, background, religion, or sexual orientation. Please note: unsolicited resumes from recruitment agencies will not be considered. #J-18808-Ljbffr Bachem Holding AG