Scientist, Vaccines and Advanced Biotechnologies (VAX) Process R&D
$87.3k - $137.4kMSD Malaysia
- # Scientist, Vaccines and Advanced Biotechnologies (VAX) Process R&DApplyremote type: Not Applicablelocations: USA - Pennsylvania - West Pointtime type: Full timeposted on: Posted Todaytime left to apply: End Date: June 20, 2026 (10 days left to apply)job requisition id: R401613**Job Description**Vaccines and Advanced Biotechnologies (VAX) Process R&D is responsible for the development and clinical manufacturing of Drug Substance (DS) and Drug Product Intermediates (DPI) for the vaccine and advanced therapy pipeline, spanning from preclinical to commercialization stages. We are part of the Process R&D organization, which enables modality-agnostic DS/DPI process development and clinical manufacturing for our company's pipeline. Our vaccines downstream process development team develops safe, scalable, robust, cost-effective downstream processes that enable clinical and commercial manufacture of vaccines and adjuvants across all vaccine modalities. We are seeking an innovative, highly motivated, and experienced Scientist to join us at our research and development site in West Point, PA. The candidate will be responsible for scientific/technical contributions and leadership of bioconjugation process development, and will also be a critical member of cross-functional program/project teams. This role will require frequent collaboration with cross-functional teams including Analytical, Formulation, Process Chemistry, Enabling Technologies, and Manufacturing colleagues. The candidate should have a strong background in downstream bioprocess/bioconjugation design, including reaction steps, filtration (tangential and normal flow) and column chromatography. **Primary responsibilities include, but are not limited to**: * Independent design, execute, and analyze process development experiments to maximize conjugate vaccine production processes, thereby de-risking later stage development and tech transfer.* Leadership roles in downstream process design and development for conjugate vaccine candidates.* Represent functional area in cross-functional and strategic teams engaged in vaccine development.* Lead tech transfer of vaccine drug substance processes for clinical and commercial manufacture.* Serve as a scientific/technical mentor. Provide technical guidance in the various aspects of downstream bioprocess/bioconjugation development.* Support strategic initiatives and innovation in the areas of vaccine and advanced biotechnology process development.* Analysis of experiments through analytical techniques including HPLC, light scattering, and spectroscopy.* Data interpretation and presentation, manuscript/patent preparation. **Education Minimum Requirement**: BS, MS or PhD in engineering or bio/chemical sciences: * Chemical Engineering, Bioengineering, Biomedical Engineering, Chemistry, Biochemistry, Molecular Biology, Biotechnology* For BS candidates, at least six (2) years of experience in a pharmaceutical or biotechnology-related position* For MS candidates, at least three (1) year of post-graduate experience in bioprocess/biotechnology-related position (vaccines and/or therapeutic proteins) or relevant academic research thesis. **Required Experience and Skill**s: * Must have scientific understanding of downstream bioprocess purification processes.* Scientific understanding of purification operations of large complex molecules.* Technical understanding of bioprocess scaling principles.* Prior hands-on bioprocess development experience through academic lab or industry experience.* Position requires employee to be willing to work with infectious agents and/or pathogens.* Position requires occasional travel and off hour/weekend work.* Strong scientific and hands-on understanding of downstream bioprocess/bioconjugation unit operations, biotherapeutic and/or vaccine process development and sound understanding of scale-up principles.* Ability to work effectively both independently and in a team-focused environment. **Preferred Experience and Skills**: * Prior hands-on experience with any of the following purification bioprocesses: Tangential Flow Filtration, Dead-End Filtration, Chromatography, or Homogenization.* Experience in Process Tech Transfer to production facilities.* Experience with biomolecule conjugation (e.g., conjugate vaccines, antibody-drug conjugates), conjugation chemistry and downstream bioconjugate processing.* Strong understanding of, or hands-on experience in, cGMP manufacturing. The successful candidate will be expected to demonstrate the ability to communicate results of their work in both verbal and written formats. They are also expected to demonstrate flexibility in responding to changing priorities or dealing with unexpected events. In addition to the core responsibilities outlined above, the candidate will be expected to comply with all required training and maintain a focused attention on laboratory safety for themselves and their team. Position may require working with infectious agents, pathogens, and/or potent compounds with appropriate engineering controls and PPE. Some travel or off-hours work may be required. #PRD **Required Skills:****Preferred Skills:**Current Employees apply HERECurrent Contingent Workers apply HERE**US and Puerto Rico Residents Only:**Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process.As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteristics. As a federal contractor, we comply with all affirmative action requirements for protected veterans and individuals with disabilities. For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit:EEOC Know Your RightsEEOC GINA SupplementWe are proud to be a company that embraces the value of bringing together, talented, and committed people with diverse experiences, perspectives, skills and backgrounds. The fastest way to breakthrough innovation is when people with diverse ideas, broad experiences, backgrounds, and skills come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another’s thinking and approach problems collectively.Learn more about your rights, including under California, Colorado and other US State ActsThe salary range for this role is$87,300.00 - $137,400.00This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An employee’s position within the salary range will be based on several factors including, but not limited to relevant education, qualifications, certifications, experience, skills, geographic location, government requirements, and business or organizational needs.The successful candidate will be eligible for annual bonus and long-term incentive, if applicable.We offer a comprehensive package of benefits. Available benefits include medical, dental, vision healthcare and other insurance benefits (for employee and family), retirement benefits, including 401(k), paid holidays, vacation, and compassionate and sick days. More information about benefits is available at can apply for this role through (or via the Workday Jobs Hub if you are a current employee). The application deadline for this position is stated on this posting.**San Francisco Residents Only:** We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance**Los Angeles Residents Only:** We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles’ Fair Chance Initiative for Hiring Ordinance**Search Firm Representatives Please Read Carefully** Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.**Employee Status:**Regular**Relocation:**No relocation**VISA Sponsorship:**No**Travel Requirements:**No Travel Required**Flexible Work Arrangements:**Not Applicable**Shift:**Not Indicated**Valid Driving License:**No**Hazardous Material(s):**n/a**Job Posting End Date:**06/20/2026**\*A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.**Our company is a global health care leader with a diversified portfolio of prescription medicines, vaccines and animal health products. The difference between potential and achievement lies in the spark that fuels innovation and inventiveness; this is the space where we have codified our legacy for over a century. Our success is backed by ethical integrity, forward momentum, and an inspiring mission to achieve new milestones in global healthcare.
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Vacancy posted 6 days ago
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