Sign up to access all features of our service.
  • Job search
  • Favorites
  • Create a CV
    New
  • Salaries
  • Subscriptions

Senior Director of Enterprise Security Architecture

$141.6k - $283.25k

RXinsider LTD.

Our team members are at the heart of everything we do. At Cencora, we are united in our responsibility to create healthier futures, and every person here is essential to us being able to deliver on that purpose. If you want to make a difference at the center of health, come join our innovative company and help us improve the lives of people and animals everywhere.

Job Details

Summary:

The Senior Director of Enterprise Security Architecture (ESA) leads the definition, governance, and enforcement of enterprise-wide security architecture strategy for the enterprise. This leader is accountable for aligning cybersecurity architecture with business strategy, digital transformation, regulatory obligations, and risk appetite. The role oversees reference architectures, security design standards, architecture review boards (ARB), security requirements engineering, and integration with Enterprise Architecture (EA), Cloud, Data, AI, Infrastructure, and Application domains. This role is responsible for building strong partnerships with technology teams, other corporate support functions, and other Information Security organizations to protect the corporate brand, data, and assets and is responsible for the design, implementation, operation, and maintenance of an information security framework, processes, and systems, that protect the business, services, information and systems against unauthorized use, disclosure, modification, damage, and loss.

The position partners closely with the CISO, other Information Security Sr. Leaders, and other Technology Leadership teams to establish a vision and strategy required to ensure scalable, measurable, and continuously improving defense capabilities across all security domains in collaboration with other information security domain leaders and partner organizations.

Our employee experience is a strategic priority for our company. Our leaders are accountable for leading with purpose, fairness, and equity. They are responsible for building and developing diverse teams, maintaining a safe and inclusive environment, setting clear priorities, and holding self and team accountable for executing with excellence.

Primary Responsibilities:

  • Define and maintain the enterprise security architecture vision and multi-year roadmap.

  • Align security architecture with corporate strategy, digital transformation, and technology modernization initiatives.

  • Establish target-state architectures incorporating Zero Trust principles in collaboration with other Information Security and Technology leaders.

  • Translate risk appetite into enforceable architectural guardrails.

  • Develop and maintain standardized reference architectures for: Cloud and hybrid infrastructure | Identity & Access Management | Data protection and privacy | Network segmentation | Application security | AI/GenAI security | OT/IoT (in partnership with OT sr. cybersecurity leadership)

  • Ensure security-by-design integration into SDLC and platform engineering models.

  • Govern architecture artifacts across global business units.

  • Chair or co-chair the Security Architecture Review Board (SARB).

  • Define security architecture review processes and risk exception workflows.

  • Establish measurable design assurance criteria.

  • Partner with Enterprise Architecture for integrated technology governance.

  • Translate regulatory and risk requirements into technical control standards.

  • Ensure compliance with global regulatory regimes (e.g., HIPAA, GDPR, SOX, FDA/GxP where applicable).

  • Maintain or enforce enterprise security standards library mapped to NIST, ISO, SOC 2, PCI, HIPAA, GDPR, etc.

  • Enable reusable security requirement models for programs and projects.

  • Drive automation of control validation and policy-as-code enforcement.

  • Support regulatory readiness across global jurisdictions.

  • Ensure architecture supports data residency and sovereignty obligations.

  • Collaborate with Legal, Privacy, and Compliance on emerging regulatory impacts.

  • Provide defensible architecture documentation for audit and regulatory review.

  • Lead security architecture assessments for acquisitions.

  • Define integration and divestiture security blueprints.

  • Support large-scale ERP, digital, AI, and cloud transformation programs.

  • Establish rapid risk assessment models for new technologies.

  • Establish KPIs, OKRs, and performance dashboards.

  • Track control design effectiveness and systemic risk reduction.

  • Integrate architecture insights with cyber analytics programs.

  • Report enterprise architecture risk posture to executive leadership.

  • Lead global team of security domain architects.

  • Define operating model across centralized and federated teams.

  • Establish architecture career paths and technical competency frameworks.

  • Enterprise financial management and planning experience.

Qualifications :

Education :

  • Bachelor’s degree in computer science, software engineering, systems engineering, information technology, cybersecurity, or a related field, or equivalent experience required.

  • Master’s Degree in Business Administration, Computer Science, Information Technology or any other related discipline or equivalent related experience.

Working Experience :

  • 12+ years of directly-related or relevant experience with 8+ years in a managerial capacity, preferably in information security.

Preferred Certifications:

  • Certified Cloud Security Professional (CCSP)

  • Certified Information Systems Security Professional (CISSP)

  • Sherwood Applied Business Security Architecture (SABSA)

  • Open Group Architecture Framework (TOGAF)

  • Certified in Risk and Information Systems Control (CRISC)

  • Certification in Information Security Strategy Management (CISM)

  • Microsoft Certified: Cybersecurity Architect Expert (SC-100)

  • Information Technology Infrastructure Library (ITIL)

  • Offensive Security Certified Professional (OSCP)

  • Project Management Professional (PMP) Certification

Behavioral Skills:

  • Coaching and Mentoring

  • Creativity & Innovation

  • Decision Making

  • Leadership Skills

  • People Management

  • Planning

  • Risk-taking

Technical Skills:

  • IT Risk Management

  • IT Controls

  • Cyber Attack Mitigation

  • Enterprise IT Management

  • Cloud Security

  • Network Security

  • Identity & Access Management

  • Application Security

  • Service Level Maintenance

  • Information Security Strategy Continuity

  • Threat Modelling

  • Information Security Strategy Standards (SOX, ISO 27001/27002, COBIT, ITIL, NIST, PCI)

Tools Knowledge:

  • Microsoft Office Suite

  • Security Tools – CSPM, CWPP, CDR, CNAPP, SIEM, EDR, Email Security Gateway, SOAR, Firewall, Anti-virus, Firewalls, VPN IDS/IPS, AV, proxies, etc.

  • Security Testing Tools - Open Source and COTS security tools

  • Threat Intelligence Tools

  • Vulnerability Testing Tools

What Cencora offers

We provide compensation, benefits, and resources that enable a highly inclusive culture and support our team members’ ability to live with purpose every day. In addition to traditional offerings like medical, dental, and vision care, we also provide a comprehensive suite of benefits that focus on the physical, emotional, financial, and social aspects of wellness. This encompasses support for working families, which may include backup dependent care, adoption assistance, infertility coverage, family building support, behavioral health solutions, paid parental leave, and paid caregiver leave. To encourage your personal growth, we also offer a variety of training programs, professional development resources, and opportunities to participate in mentorship programs, employee resource groups, volunteer activities, and much more. For details, visit

Full time

Salary Range*

$141,600 - 283,250

*This Salary Range reflects a National Average for this job. The actual range may vary based on your locale. Ranges in Colorado/California/Washington/New York/Hawaii/Vermont/Minnesota/Massachusetts/Illinois State-specific locations may be up to 10% lower than the minimum salary range, and 12% higher than the maximum salary range.

Equal Employment Opportunity

Cencora is committed to providing equal employment opportunity without regard to race, color, religion, sex, sexual orientation, gender identity, genetic information, national origin, age, disability, veteran status or membership in any other class protected by federal, state or local law.

The company’s continued success depends on the full and effective utilization of qualified individuals. Therefore, harassment is prohibited and all matters related to recruiting, training, compensation, benefits, promotions and transfers comply with equal opportunity principles and are non-discriminatory.

Cencora is committed to providing reasonable accommodations to individuals with disabilities during the employment process which are consistent with legal requirements. If you wish to request an accommodation while seeking employment, please call View phone number on click.appcast.io or email View email address on click.appcast.io. We will make accommodation determinations on a request-by-request basis. Messages and emails regarding anything other than accommodations requests will not be returned

.

Affiliated Companies:

AmerisourceBergen Services Corporation

#J-18808-Ljbffr

Vacancy posted 21 hours ago
Similar jobs that could be interesting for youBased on the Senior Director of Enterprise Security Architecture in Pennsylvania vacancy
  •  ...Cencora is seeking a Senior Director of Enterprise Security Architecture to lead the definition, governance, and enforcement of enterprise-wide security architecture strategy. You will align security with business strategy, manage reference architectures, and partner with... 
    Senior

    Jobleads-US

    Pennsylvania
    10 hours ago
  •  ...Us:BW Design Group is a fully integrated architecture, engineering, construction, system...  ...fulfillment.When you join Design Group as a Senior Manager, Sales & Business Development Operations...  ..., and highly flexible path. As a Director, you will build a meaningful and fulfilling... 
    Senior
    Full time
    Contract work
    Work at office
    Flexible hours

    Barry-Wehmiller

    Philadelphia, PA
    2 days ago
  •  ...Cencora is seeking a senior cloud architect to define and govern enterprise solution architectures across Microsoft Azure and AWS. You will lead cloud modernization initiatives...  ...translate business strategy into scalable, secure, and cost-effective enterprise solutions while... 
    Senior

    Jobleads-US

    Conshohocken, PA
    4 days ago
  • $141.6k - $283.25k

     ...people and animals everywhere. Job Details Summary: The Senior Director of Cloud Security leads the global strategy, architecture, engineering, and governance of cloud security for an enterprise operating in multi-cloud and hybrid environments. This role is accountable... 
    Senior
    Full time
    Work experience placement
    Work at office
    Local area

    RXinsider LTD.

    Pennsylvania
    21 hours ago
  •  ...Position Summary We are seeking a Senior Principal Engineer to define...  ...the end to end technical architecture of the Bentley Developer...  ...platform's API design standards, security models, and integration...  ...with the CIO organization on enterprise application and ERP integration... 
    Senior
    Work at office
    Worldwide

    Bentley Systems

    Philadelphia, PA
    2 days ago
  • $158k - $217k

     ...capabilities. This role is ideal for a senior technical leader who can move...  ...conversations, solution architecture, partner strategy, and hands-...  ...are achievable, well-scoped, secure, governed, and aligned to...  ...Global 1000, many successful enterprise and mid-market companies, and... 
    Senior
    Temporary work
    Local area

    Slalom

    Philadelphia, PA
    3 days ago
  • $215k - $275k

     ...platforms that can operate safely at enterprise scale. As an AI/ML Architect, you’ll...  ...clients to shape strategy, define secure and governed architectures, and move AI solutions from experimentation...  ..., and thought leadership.* Develop senior practitioners and practice... 
    Senior
    Temporary work
    Local area

    Slalom

    Philadelphia, PA
    3 days ago
  • Manager/Senior Manager for Biologics, Cell, and Gene Therapy Operations (BCGT)Location: Exton, PAFull TimeFrontage Laboratories Inc. is an award winning, full-service, CRO/Contract Research Organization operating over 25 state-of-the-art laboratories across the US, Canada... 
    Senior
    Contract work

    Frontage Laboratories

    Exton, PA
    3 days ago
  •  ...00+ team of professionals works collaboratively across multiple service areas in multiple states, including planning, landscape architecture, civil engineering, surveying, and construction engineering. We are a team of experts with individual specialties working together... 
    Senior
    Temporary work
    Local area
    Flexible hours

    OHM Advisors

    Pittsburgh, PA
    16 days ago
  •  ...- 10 years successful management experience with primary focus in operations and manufacturing-related processes; 4 of these at a senior level leading salaried employees.Previous experience with Metal Fabrication/Assembly Systems/Painting preferredDemonstrated ability... 
    Senior
    Full time
    Work at office
    Shift work

    Design Within Reach

    East Greenville, PA
    1 day ago
  •  ...people and animals everywhere. Defines enterprise solution architecture direction across interdependent...  ...and technology strategy into scalable, secure, resilient, and supportable solution...  ...tradeoffs, and decision agendas clearly with senior leaders, cross-functional... 
    Senior
    Temporary work
    Local area

    Jobleads-US

    Conshohocken, PA
    4 days ago
  • Work Flexibility: RemoteThe Coupa Operations Senior Manager (Remote) plays a pivotal role in driving operational excellence across global Procure-to-Pay (P2P) processes. Reporting to the Senior Director of Indirect Programs and Strategy, this leader oversees a multi-national... 
    Senior
    Full time
    Contract work
    For contractors
    Remote work

    Stryker

    Pittsburgh, PA
    3 days ago
  •  ...HSN, Ballard Designs, Frontgate, Garnet Hill and Grandin Road.Your Opportunity, Your TeamThe Senior Manager, Total Rewards Operations supports QVC, reporting to the Senior Director, Total Rewards, and leads the day-to-day administration, governance, process improvement,... 
    Senior
    Full time
    Local area
    Relocation package

    QVC

    West Chester, PA
    5 days ago
  •  ...multi-day events within a technology company. Experience with enterprise technology events or other high-visibility corporate programs...  ...of a world-leading software company providing solutions for architecture, engineering, and construction - watch this short documentary... 
    Remote work
    Work from home
    Worldwide

    Bentley Systems

    Philadelphia, PA
    5 days ago
  •  ...invoice query resolution.Support Renewal Representatives and Enterprise Analysts on contract renewals, providing invoice and contract...  ...of a world-leading software company providing solutions for architecture, engineering, and construction - watch this short documentary... 
    Contract work
    Worldwide

    Bentley Systems

    Exton, PA
    2 days ago
  •  ...line to the SVP, Legal, and a close partnership with our VP, Security & Compliance. If you like building things and don’t need a playbook...  ...ForHands-on ownership of a CLM implementation or a comparable enterprise systems rollout, from requirements through adoptionWorking... 
    Senior
    Contract work
    Visa sponsorship

    IntegriChain

    Philadelphia, PA
    3 days ago
  •  ...in digital, cloud and security. Combining unmatched...  ...seeking an experienced Senior Manager, AIOps &...  ...Advisory to help large enterprises move from reactive, human...  ...agentic operations architectures grounded in real...  ...Infrastructure, NOC Director, or equivalent) before... 
    Senior
    Full time
    Work experience placement
    Live in
    Work at office
    Local area
    Night shift

    Accenture

    Philadelphia, PA
    3 days ago
  •  ...solutions and services company that helps the world’s leading enterprises reinvent by building their digital core and unleashing the power...  ...and solutions. You are comfortable leading teams, advising senior stakeholders, and working across business, operations, and technology... 
    Senior
    Full time
    Work experience placement
    Live in
    Work at office
    Local area

    Accenture

    Philadelphia, PA
    3 days ago
  • $139.1k - $231.9k

     ...hybrid environments.    The CD organization is part of a broader security organization at Pfizer called CISO.  The CISO organization...  ...breakthroughs that change patients’ lives.     Why This Role MattersThe Senior Manager - Response Threat Operations will report into the... 
    Senior
    Permanent employment
    Full time
    H1b
    Local area
    Visa sponsorship
    Work visa
    Relocation package

    Pfizer

    Collegeville, PA
    5 days ago
  • Job Summary:A Tax Senior Manager, Business Incentives Group (BIG) is charged with helping clients identify, document, and support tax positions related to their BIG tax credits and deductions. The BIG Senior Manager is a critical member of the BIG leadership team and actively... 
    Senior
    Work at office

    BDO International

    Philadelphia, PA
    5 days ago
  • $116.93k - $133.64k

    STV is seeking a Senior Engineering Operations Manager to serve as a trusted operations leader and subject matter expert supporting transit and rail clients nationwide. This highly consultative role partners directly with agency leadership to guide operational strategy... 
    Senior
    Full time
    Work at office
    Flexible hours

    STV Group

    Philadelphia, PA
    3 days ago
  • $85k - $100k

     ...Senior Operations Manager (Operations Manager I)The Sr. Operations Manager (Operations Manager I) role has a national salary range of $85,000 - $100,000. For roles within California and Washington the range is $85,000 to $110,000. DHL Supply Chain offers multiple benefits... 
    Senior
    Contract work
    Casual work

    DHL

    Taylor, PA
    2 days ago
  • $132k - $205k

     ...training resources. Conduct or review research of complex or new controls, accounting and information security issues and prepare memorandums to support solutions. Keep Directors and Partners informed about client updates, engagement and budget to actual status, and... 
    Senior
    Full time
    Contract work
    Work at office
    Local area
    Flexible hours

    Armanino

    Philadelphia, PA
    3 days ago
  •  ...Senior Project Architect At Array Architects, we're not just creating spaces; we're redefining the future of healthcare environments through innovative design and unparalleled excellence. As we embark on our next chapter, we're searching for a Senior Project Architect... 
    Senior
    Work at office

    Array Architects

    Conshohocken, PA
    2 days ago
  •  ...new ways of working in an industry that historically has resisted innovation. Join us!ABOUT THE ROLEBlink Health is looking for a Senior Program Manager, People Operations to own our Leave of Absence and Accommodations programs end-to-end, while bringing deep People Ops... 
    Senior
    Local area
    Flexible hours

    Blink Health

    Pittsburgh, PA
    4 days ago
  • $77k - $202k

     ...OpportunityAs a Manufacturing Operations Excellence Consultant, Senior Associate, you will specialize in optimizing operational efficiency...  ...members. We evaluate these factors thoughtfully to establish a secure and trusted workplace for all.Applications will be accepted... 
    Senior
    Full time
    H1b

    PwC

    Pittsburgh, PA
    4 days ago
  •  ...multi-day events within a technology company. Experience with enterprise technology events or other high-visibility corporate programs...  ...of a world-leading software company providing solutions for architecture, engineering, and construction - watch this short documentary... 

    Bentley

    Philadelphia, PA
    4 days ago
  •  ...Job Description As a Senior Manager - Operations you will manage multiple priorities in a customer-centered environment. While leading...  ...customer value added services. Maintains a safe, secure and inclusive workplace. Manages, coaches, mentors, hires and... 
    Senior
    Immediate start
    Worldwide
    Shift work

    WESCO International

    Lemoyne, PA
    1 day ago
  •  ...for defining, designing, and driving the next generation of Securities Lending operating models, workflows, technology capabilities,...  ...expertise in process improvement, workflow design, operational architecture, and transformation initiativesStrong project and program... 
    Full time
    Local area

    Vanguard

    Malvern, PA
    2 days ago
  • $190k - $210k

     ...focused technology leader to oversee the enterprise business systems portfolio supporting...  ...the Chief Information Officer, the Senior Director, of Business Applications will drive...  ...Platform Engineering for application architecture, technical design, development, and integrations... 
    Senior
    Local area
    Work from home
    2 days per week

    Culligan Quench

    King of Prussia, PA
    4 days ago

Do you want to receive more vacancies?

Subscribe and receive similar vacancies to Senior Director of Enterprise Security Architecture. Be the first to apply!