Executive Medical Director, Global Medical Lead (Pain)

General Summary The Executive Medical Director, Global Medical Lead (GML), Pain is a critical leadership role in Global Medical, responsible for the global medical strategy and implementation and tracking of global activities for a designated disease area(s). The GML leads disease area specific integrated medical plan development including publication plan, global launch strategy and execution, scientific leadership, external medical expert engagement, and strategic alignment with commercial and cross‑functional partners. This leader also drives post‑approval evidence generation strategy and reports to the VP, Global Medical. Key Duties and Responsibilities Medical Strategy Lead development, implementation, execution, and communication of Integrated Medical Plans, including medical strategy, global tactical plan, publication plan, congress and post‑approval evidence generation plan. Ensure alignment of medical strategy with organizational objectives by integrating individual and disease‑area team goals with Vertex and DST priorities. Distill insights and actionable outcomes that inform strategy and drive impact for Medical Affairs. Establish and track medical KPIs that demonstrate impact on business and patient outcomes. Apply structured problem‑solving and root cause analysis to identify solutions and make decisions that maximize medical and business impact. Prioritize competing demands and communicate to key stakeholders. Accountable for development of the global DA budget, management of funds allocation, and tracking to align with Medical Affairs priorities and efficient resource allocation. Scientific Excellence Serve as product and disease‑area expert and primary contact for external community and internal stakeholders. Lead development of peer‑reviewed publications, congress presentations, and evidence generation to shape clinical practice. Follow medical developments within disease area and disseminate new information to transform clinical trends. Lead development of global scientific communications and materials, including for symposia, advisory boards, and training. Provide medical review of brand‑related content and global medical content aligned with Vertex SOPs. External Partnerships Represent Vertex at scientific and medical forums, including education forums, scientific societies, patient advocacy groups, and congresses. Engage and cultivate relationships with leading global key thought leaders to understand unmet patient needs. Medical Communication Tailor communication to stakeholder needs, building trust and understanding across diverse audiences. Deliver external presentations (advisory board meetings, symposia, medical education meetings) in accordance with regulations. Support disease area training across the company. Responsibly interpret data (clinical trials, registries, literature) for pipeline therapies and marketed medicines. Regional Medical and Cross‑Functional Collaboration Accountable for go‑to‑market model and medical partnership in commercialization with global cross‑functional colleagues. Support regional Medical Affairs and Medical Excellence teams from launch through lifecycle via timely delivery of fit‑for‑purpose training and core materials. Drive alignment on medical content/messaging within the organization. Lead key global cross‑functional product and development teams, including DST and sub‑teams. Adapt communication of DST priorities to medical function and proactively represent medical needs to DST. Chair the Global Medical Area Team (GMAT) for the disease area and accountable for deliverables. Provide strategic Medical Affairs leadership on launch teams and global brand teams. Represent Medical Affairs in label discussions. Support Access, Patient Advocacy, Policy, and Corporate Communications teams with expertise and materials review. Evidence Generation and Access Lead strategy, development, and execution of Life Cycle Management in partnership with HEOR, including Integrated Evidence Generation plan. Act as medical monitor for studies under Medical Affairs scope in collaboration with Clinical Development, RWE, HEOR, and Clinical Operations. Lead oversight and management of ISS programs; conduct scientific review of ISS protocols with Regional Medical leadership. Lead Managed Access Committee for assets with a Managed Access Program (MAP) and act as Medical Monitor for MAP. Team / People Management Provide strong leadership to a dedicated disease‑area medical team, inspire and empower, and promote continuous development. Accountable for recruitment, development, management, and coaching of the global medical team. Leverage team capabilities to ensure successful execution of medical plans. Identify and address skill gaps, accelerating internal talent or attracting external talent. Adhere to formal goal‑setting, talent, and performance cycles, ensuring IDPs are in place. Navigate ambiguity and coach team during periods of uncertainty or change. Compliance and Pharmacovigilance Ensure compliance of medical activities with global and regional guidelines, Vertex Code of Conduct, regulations, policies, SOPs, GCP, and ICH. Ensure self and colleagues have skills to identify and report AEs appropriately. Contribute to managing external communication when significant safety issues arise, with patient wellbeing as the ultimate goal. Education and Experience MD, PhD, PharmD or other advanced life sciences degree required. Typically requires 15 years of experience and 7 years of supervisory/management experience, or equivalent. 6 or more years of relevant leadership experience in medical affairs and/or clinical development, including global and country/region experience. 2 or more years of industry experience in the disease area. Pay Range $328,000 - $492,000 Disclosure Statement The range provided is a reasonable estimate for the base salary at the time of posting. The role is eligible for an annual bonus, equity awards and may be eligible for overtime pay in accordance with federal and state requirements. Base salary will be based on factors including skills, experience, and other job‑related factors permitted by law. Vertex offers inclusive market‑leading benefits such as medical, dental, vision, generous paid time off, educational assistance, commuting subsidy, charitable donations, 401(k) and more. Flex Designation Hybrid‑Eligible or On‑Site Eligible Flex Eligibility Status In this Hybrid‑Eligible role, you can choose to be designated as: Hybrid: work remotely up to two days per week. On‑Site: work five days per week on‑site with ad‑hoc flexibility. Note: The Flex status is subject to Vertex's Flex @ Vertex Program and may change at any time. Company Information Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non‑discrimination for all employees and qualified applicants without regard to race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or other characteristics protected under applicable law. Vertex is an E‑Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring accommodation in the hiring process or to perform essential functions of the position should make a request to the recruiter or hiring manager, or contact Talent Acquisition at View email address on click.appcast.io. #J-18808-Ljbffr Vertex Pharmaceuticals Incorporated