Postdoctoral Fellow - Tumor Microbiology, Cancer Cell Biology and Genomics

Postdoctoral Fellow - Tumor Microbiology, Cancer Cell Biology and Genomics Overview The Bullman Laboratory at the Department of Immunology, chaired by Dr. James P. Allison, is seeking a highly motivated Postdoctoral Fellow to join our interdisciplinary and collaborative team. Our lab includes clinical microbiologists, computational biologists, biochemists, and cancer geneticists united by a mission to improve the diagnosis and treatment of human cancer, with a focus on gastrointestinal cancers, ultimately aiming to extend the lives of cancer patients. Utilizing cutting-edge technologies, we integrate human data sets with in vivo and in vitro models to investigate the role of tumor-infiltrating bacteria in cancer progression, metastasis, treatment resistance, and the tumor microenvironment (TME). We are recruiting a Postdoctoral Fellow with a strong background in cancer cell biology, lineage tracing, and cell and molecular biology. The position will focus on uncovering how tumor-infiltrating bacteria influence the TME and cellular functions, ultimately contributing to treatment resistance, cancer progression, and metastasis. Prior experience with microbiome research is not required, as ample training will be provided, though an interest in this area is essential. Responsibilities Explore host-microbe interactions in gastrointestinal cancer microbiota and the TME using advanced spatial imaging technologies, single-cell sequencing, and functional genomics approaches. Perform lineage tracing and investigate cellular and molecular pathways impacted by tumor-associated bacteria. Leverage genomics and transcriptomics data, as well as preclinical models, to decipher the mechanisms of bacterial impact on cancer progression. Engage in collaborative, cross-disciplinary research with access to state-of-the-art facilities and tools. Acquire professional development and expertise in single-cell sequencing, tissue imaging approaches, functional genomics, and translational research planning and strategy. All duties and responsibilities are carried out in compliance with institutional policies, ethical research standards, and applicable federal and state regulations. Eligibility Requirements Ph.D. in biological sciences, cancer biology, cell and molecular biology, microbiology, computational biology, or a related field. Demonstrated expertise in cancer cell biology, lineage tracing, and cell and molecular biology techniques. A track record of scientific productivity, as evidenced by peer-reviewed publications. Strong collaboration, curiosity, creativity, and organizational skills. Dedication to advancing fundamental knowledge of the cancer microbiome and translating findings into innovative therapeutic strategies. Position Information MD Anderson offers full-time postdoc positions with a salary ranging from $64,000 to $76,000, depending on the number of years of postgraduate experience. The University of Texas MD Anderson Cancer Center offers excellent benefits, including medical, dental, paid time off, retirement, tuition benefits, educational opportunities, and individual and team recognition. Offsite work arrangements are subject to approval and may be modified or revoked at any time based on business needs, performance considerations, or regulatory requirements. This position may be responsible for maintaining the security and integrity of critical infrastructure, as defined in Section 113.001(2) of the Texas Business and Commerce Code and therefore may require routine reviews and screening. The ability to satisfy and maintain all requirements necessary to ensure the continued security and integrity of such infrastructure is a condition of hire and continued employment. It is the policy of The University of Texas MD Anderson Cancer Center to provide equal employment opportunity without regard to race, color, religion, age, national origin, sex, gender, sexual orientation, gender identity/expression, disability, protected veteran status, genetic information, or any other basis protected by institutional policy or by federal, state or local laws unless such distinction is required by law. #J-18808-Ljbffr