Sign up to access all features of our service.
  • Job search
  • Favorites
  • Create a CV
    New
  • Salaries
  • Subscriptions

Principal AI Engineer

$206.6k - $284.3k

Humana CenterWell Home Health Orangeburg

Become a part of our caring community
Every large organization is making critical decisions today about how it will leverage AI over the next decade. Few have leaders who can both define that vision and demonstrate its viability through hands-on engineering. This role requires both.

We build the platform that transforms millions of clinical documents into trusted, actionable data. Our systems use large language models (LLMs) to read medical records, extract structured facts, answer complex questions with citations to source documents, and route difficult cases to human experts. These capabilities support decisions that impact real healthcare outcomes for members.

As a Principal AI Applied Engineer, you will define the technical strategy, architectural standards, and long-term vision for AI-enabled products across the organization. You will influence enterprise-wide decisions regarding AI platforms, model strategies, engineering standards, and technology investments while remaining deeply hands-on in prototyping, experimentation, architecture, and software development.

This is the highest-level individual contributor role within the AI Applied Engineering organization. Success requires exceptional technical depth, organizational influence, strategic thinking, and the ability to translate emerging AI capabilities into scalable, reliable, and responsible production systems.

Why Join Us
  • Shape the long-term AI architecture and engineering direction for a large enterprise healthcare organization.
  • Influence how AI-enabled products are designed, built, evaluated, deployed, and governed across multiple teams.
  • Drive strategic decisions involving models, vendors, platforms, infrastructure, and shared capabilities.
  • Prototype and validate emerging technologies before the organization invests at scale.
  • Establish engineering standards and platform capabilities that will influence the business for years to come.
  • Solve complex challenges involving trust, explainability, compliance, reliability, and operational excellence in AI systems.
  • Work on systems that process healthcare information at significant scale and directly support member outcomes.
  • Remain hands-on with architecture, software development, experimentation, and technical problem solving.
Key Responsibilities
  • Define and drive the long-term technical strategy, reference architecture, and technology roadmap for AI-enabled products and platforms.
  • Establish architectural patterns and best practices for retrieval systems, LLM orchestration, agentic workflows, human-in-the-loop processes, evaluation frameworks, and AI governance.
  • Lead organization-wide technical decision-making regarding model strategy, vendor selection, platform investments, build-versus-buy decisions, and shared infrastructure capabilities.
  • Design and champion scalable architectures that balance reliability, performance, security, compliance, maintainability, and cost efficiency.
  • Establish engineering standards for evaluation, observability, model lifecycle management, responsible AI practices, and operational excellence.
  • Build prototypes, proofs of concept, and reference implementations that de-risk emerging technologies and strategic platform investments.
  • Lead cross-functional architecture reviews and provide technical guidance across multiple engineering teams.
  • Mentor Lead Engineers, Senior Engineers, and emerging technical leaders through architecture reviews, design feedback, coaching, and technical sponsorship.
  • Develop and communicate technical roadmaps aligned with business strategy and organizational objectives.
  • Partner with executive leadership to translate business priorities into technical strategies and communicate technical opportunities, risks, and tradeoffs.
  • Represent engineering in strategic vendor evaluations, compliance discussions, governance reviews, and enterprise planning initiatives.
  • Drive adoption of common platforms, standards, and engineering practices across teams.
  • Ensure AI systems are designed and operated in accordance with privacy, security, compliance, governance, and auditability requirements.
Use your skills to make an impact

Required Qualifications
  • Bachelor's degree in Computer Science, Engineering, or a related technical field, or equivalent practical experience.
  • 12+ years of software engineering experience, including extensive experience designing and operating large-scale distributed systems.
  • Proven track record of designing, delivering, and operating production AI-enabled platforms or products at enterprise scale.
  • Deep expertise in large language model technologies, AI platform design, retrieval-augmented generation (RAG), agentic systems, orchestration frameworks, evaluation methodologies, and AI operations.
  • Extensive experience designing cloud-native architectures and highly scalable, resilient systems.
  • Demonstrated ability to define technical direction that influenced teams, organizations, or product portfolios beyond direct reporting relationships.
  • Experience establishing engineering standards, architectural frameworks, or technical platforms that have been successfully adopted across multiple teams.
  • Strong understanding of AI operational challenges, including model reliability, latency, cost optimization, governance, observability, and risk management.
  • Demonstrated success influencing executive stakeholders and driving organizational decisions through technical leadership and evidence-based recommendations.
  • Expert-level proficiency in Python and/or TypeScript/JavaScript.
  • Ability to prototype, debug, review, and contribute code across multiple layers of the technology stack.
Preferred Qualifications
  • Experience leading AI platform strategy across multiple business units or product organizations.
  • Experience developing enterprise standards for AI evaluation, testing, observability, governance, and responsible AI practices.
  • Expertise evaluating and managing AI vendor ecosystems across multiple model providers and platform technologies.
  • Experience building shared AI infrastructure and platform capabilities consumed by multiple engineering teams.
  • Experience with agentic architectures, Model Context Protocol (MCP), workflow orchestration, autonomous systems, and emerging AI frameworks.
  • Experience operating AI systems at significant scale while managing performance, reliability, and cost tradeoffs.
  • Experience working in regulated industries such as healthcare, financial services, life sciences, or government.
  • Deep understanding of privacy, security, compliance, governance, and risk management requirements in highly regulated environments.
  • Experience driving adoption of AI-assisted software development practices across engineering organizations.
  • Experience advising executive leadership on emerging technologies, platform strategy, and enterprise architecture decisions.
  • Exceptional communication, leadership, collaboration, and strategic problem-solving skills.
Leadership Expectations
  • Serve as the highest-level technical authority within the AI Applied Engineering organization.
  • Influence organizational outcomes through technical excellence, credibility, and demonstrated results rather than formal authority.
  • Balance innovation with operational discipline and long-term sustainability.
  • Establish scalable technical standards that enable teams to move faster while maintaining quality and reliability.
  • Drive alignment across engineering, product, business, clinical, compliance, and executive stakeholders.
  • Build organizational capability by mentoring and developing the next generation of technical leaders.
  • Foster a culture of engineering rigor, continuous learning, accountability, and responsible AI development.
Success in This Role

Successful candidates are respected technical leaders who combine strategic thinking with hands-on execution. They influence organizations through technical expertise, data-driven decision-making, and working solutions rather than formal authority alone.

You are energized by difficult, long-horizon problems and are comfortable making high-impact decisions that affect multiple teams and products. You view AI architecture, governance, reliability, and responsible deployment as critical engineering disciplines, not afterthoughts.

Most importantly, you remain a builder. Your strategies are informed by real experience developing, testing, and operating production systems, and your credibility comes from your continued ability to solve hard technical problems through architecture, experimentation, and code.

Technology Stack
  • TypeScript
  • React / Next.js
  • Python
  • PostgreSQL
  • Gemini on Vertex AI
  • OCR and Document AI technologies
  • Docker
  • Kubernetes
  • Modern CI/CD platforms and tooling

Additional Information

This role operates in a highly regulated environment where responsible handling of sensitive and protected information is fundamental. Success requires a commitment to building secure, compliant, auditable, and trustworthy AI systems that meet the highest standards for privacy, reliability, and quality.

Work Style: This position follows a hybrid work schedule, requiring employees to work three days per week in the office and the remaining days remotely. Qualified candidates must currently reside within, or be willing to relocate to, a commutable distance from one of the talent markets.

Scheduled Weekly Hours

40

Pay Range
The compensation range below reflects a good faith estimate of starting base pay for full time (40 hours per week) employment at the time of posting. The pay range may be higher or lower based on geographic location and individual pay will vary based on demonstrated job related skills, knowledge, experience, education, certifications, etc.

$206,600 - $284,300 per year

This job is eligible for a bonus incentive plan. This incentive opportunity is based upon company and/or individual performance.

Description of Benefits
Humana, Inc. and its affiliated subsidiaries (collectively, "Humana") offers competitive benefits that support whole-person well-being. Associate benefits are designed to encourage personal wellness and smart healthcare decisions for you and your family while also knowing your life extends outside of work. Among our benefits, Humana provides medical, dental and vision benefits, 401(k) retirement savings plan, time off (including paid time off, company and personal holidays, paid parental and caregiver leave), short-term and long-term disability, life insurance and many other opportunities.

About Us
About Humana: Humana Inc. (NYSE: HUM) is a leading U.S. healthcare company. Through our Humana insurance services and our CenterWell healthcare services, we make it easier for the millions of people we serve to achieve their best health - delivering the care and service they need, when they need it. These efforts are leading to a better quality of life for people with Medicare and Medicaid, families, individuals, military service personnel, and communities at large. Learn more about what we offer at Humana.com and at CenterWell.com.

Equal Opportunity Employer

It is the policy of Humana not to discriminate against any employee or applicant for employment because of race, color, religion, sex, sexual orientation, gender identity, national origin, age, marital status, genetic information, disability or protected veteran status. It is also the policy of Humana to take affirmative action, in compliance with Section 503 of the Rehabilitation Act and VEVRAA, to employ and to advance in employment individuals with disability or protected veteran status, and to base all employment decisions only on valid job requirements. This policy shall apply to all employment actions, including but not limited to recruitment, hiring, upgrading, promotion, transfer, demotion, layoff, recall, termination, rates of pay or other forms of compensation and selection for training, including apprenticeship, at all levels of employment.
Vacancy posted 19 hours ago
Similar jobs that could be interesting for youBased on the Principal AI Engineer in New York, NY vacancy
  • $207k - $340k

     ...determined by the business needs of the team. This role will  be based in New York, NY . Responsibilities: As a Principal AI Engineer you will be setting the technical direction and foundation to build and own algorithms, models, and systems that power our LinkedIn... 
    Suggested
    Full time
    For contractors
    Work experience placement
    Work at office
    Flexible hours

    Linkedin

    New York, NY
    19 hours ago
  • $200k - $245k

     ...Turing is the world’s leading research accelerator for frontier AI labs and a trusted partner for global enterprises looking to deploy...  .... You will be required to work with a team of other Turing engineers across different skill sets. In the past, the Turing GenAI delivery... 
    Suggested
    Full time
    Flexible hours

    Turing

    New York, NY
    19 hours ago
  •  ...Medical Center is accelerating the safe and rigorous use of AI in research and healthcare delivery. We build agentic AI solutions...  ...of agentic AI platforms. We have an immediate opening for a Principal AI Engineer to help lead this work. The ideal candidate is a talented and... 
    Suggested
    Temporary work
    Local area
    Immediate start
    Monday to Friday

    Columbia University in the City of New York

    New York, NY
    4 days ago
  •  ...Principal AI Engineer Midtown Manhattan, New York City At our consulting company, we solve the most complex and critical challenges by moving quickly from analysis to action when it really matters; creating value that has a lasting impact on companies, their people... 
    Suggested
    Full time
    Work at office
    Remote work
    Relocation package

    Phizenix

    New York, NY
    48 minutes ago
  • $200k - $245k

     ...progress. Headquartered in San Francisco, Turing works with frontier AI labs to generate high-quality datasets, reinforcement learning...  ...benchmarks that improve model capabilities in software engineering, enterprise knowledge work, and advanced STEM reasoning. In software... 
    Suggested

    Turing Inc

    New York, NY
    3 days ago
  •  ...Job Description Job Description Principal AI Engineer Recruits Lab exists to connect exceptional life sciences and technology talent with organizations that need them—through relationships, not volume. As Principal AI Engineer you will turn that mission into production... 
    Live in
    Remote work

    Recruits Lab

    New York, NY
    2 days ago
  • $185k - $264.5k

     ...Location Designation: Hybrid - 3 days per week  Technology, Data, AI and Ventures: Within the Tech, Data, AI, Ventures (TDAV)...  ...of a mutual company built to last. Role Overview As a Principal AI Engineer within the Artificial Intelligence & Data (AI&D) organization... 
    Local area
    3 days per week

    New York Life Insurance Co

    New York, NY
    17 days ago
  •  ...safeguards Fortune 500 enterprises worldwide. Learn more at appgate.com. About the Role We're looking for a AI/ML Engineer (Senior/Staff/Principal) - Threat Detection who will design, build, and operationalize the detection algorithms, ML inference pipelines,... 
    Full time
    For contractors
    Worldwide

    Appgate Cybersecurity, Inc.

    New York, NY
    19 hours ago
  • $150k - $210k

     ...the future of our communities. We have multiple Software Engineering positions open at Associate, Director and VP levels, which are...  ..., code quality) Learn and apply new technologies, including AI/ML and prompt‑based approaches , where they add value What... 
    Full time
    Temporary work
    Worldwide

    Morgan Stanley

    New York, NY
    a month ago
  •  ...DataCamp's mission is to empower everyone with the data and AI skills essential for 21st-century success. By providing practical...  ...+ years building complex LLM-based systems, with strong prompt engineering intuition and experience designing agentic workflows. ~ Ability... 
    Remote work
    Work from home
    Flexible hours

    DataCamp

    New York, NY
    10 days ago
  •  ...a career in Advisory. KPMG is currently seeking a Director, AI Strategy Architect to join our Advisory Services practice. Responsibilities...  ..., ensuring the team stays at the forefront of AI and cloud engineering technology advancements Work closely with our Microsoft,... 
    H1b
    Local area

    KPMG

    New York, NY
    3 days ago
  • $195k - $323k

     ...that help people, businesses and governments realize their greatest potential. Title and Summary Director, Forward-Deployed AI Engineer - AI Mobilization & Transformation Overview The Director, Forward-Deployed AI Engineer serves as Mastercard's embedded AI... 
    Full time
    Part time
    Local area
    Worldwide
    Flexible hours

    MasterCard

    New York, NY
    4 days ago
  •  ...Job Description Job Description Director of AI Engineering Recruits Lab connects specialized life-sciences and technology talent with organizations that need them—through relationships, not volume. You will turn that model into a durable advantage: production AI... 
    Live in

    Recruits Lab

    New York, NY
    2 days ago
  • $147.5k - $211k

     ...Location Designation: Hybrid - 3 days per week  Technology, Data, AI and Ventures: Within the Tech, Data, AI, Ventures (TDAV)...  ...company built to last. Role Overview As a Director, AI Engineering in the Artificial Intelligence & Data (AI&D) organization, you... 
    Live in
    Local area
    3 days per week

    New York Life Insurance Co

    New York, NY
    17 days ago
  • $149.82k - $198.37k

     ...Are you ready to join a company with a strong purpose and a winning culture? Start your Voyage -Apply NowProfile Summary:The AI Principal Engineer (IC Director) role is responsible for leading the design and delivery of complex, production-grade AI systems with... 
    Full time
    Part time
    Work experience placement
    Local area
    Work from home
    Flexible hours

    Benefitfocus

    New York, NY
    6 days ago
  •  ...About Build AI for the Built World: Build has created the agentic AI stack for institutional real estate, automating complex development and acquisitions workflows 90% faster than humans to accelerate the world's most important built projects - digital infrastructure... 
    Full time
    Live in

    Build Technologies

    New York, NY
    19 hours ago
  • $35 - $50 per hour

     ...Location: Remote (Global) Reports to: Director of Engineering Company: Supernal Type: Contractor or EOR FTE Rate: $35-50/hr About Supernal At Supernal, we help SMBs hire their first AI employee. Our AI teammates are built with intelligent, agentic workflows... 
    Remote job
    Full time
    For contractors

    Infinity

    New York, NY
    19 hours ago
  • $180k - $240k

     ...Forward Deployed Software Engineer — US / NYC About Indicium AI Indicium AI was Anthropic’s first European launch partner, a Preferred Anthropic Partner, and sits among a handful of organizations globally trusted to deploy Claude at an enterprise scale. Named... 
    Full time
    Flexible hours

    Indicium Ai

    New York, NY
    19 hours ago
  • $175k - $275k

     ...decisions. Translucent is changing that. We're building the agentic AI platform designed exclusively for healthcare finance- giving...  ...is the place. Role Overview We're looking for an AI Engineer to help build the agentic platform at the core of Translucent: the... 
    Full time
    Work at office

    Translucent Inc

    New York, NY
    19 hours ago
  • $130k - $150k

     ...accessible financial markets. Our risk management systems, oracles, and AI models secure over $200 billion in assets across protocols...  ...to everyone. The Role: We're looking for a Senior AI Engineer to design and build the agentic systems powering Chaos AI. You'll... 
    Full time

    Decircle

    New York, NY
    19 hours ago
  • $135k - $200k

     ...develop lifesaving drugs, forecast supply chain disruptions, locate missing children, and more. The Role Forward Deployed AI Engineers work directly with customers owning Gen AI strategy and implementation. On a daily basis, you will build end-to-end workflows,... 
    Full time
    Work experience placement
    Work at office
    Remote work
    Work from home
    Relocation package
    Flexible hours

    Palantir Technologies

    New York, NY
    19 hours ago
  •  ...Job description Rengo AI is building the intelligence layer for fund management — starting with next-generation portfolio monitoring...  ...assets and strategies . The Role As a Founding AI Engineer , you will build the core system that powers AI-driven... 
    Full time
    Shift work

    Decircle

    New York, NY
    19 hours ago
  • $150k - $195k

     ...our mission is to make intelligent agents ubiquitous. We build the foundation for agent engineering in the real world, helping developers move from prototypes to production-ready AI agents that teams can rely on. We began as widely adopted open-source tools and have grown... 
    Full time
    Live in
    Work at office
    Flexible hours

    LangChain

    New York, NY
    19 hours ago
  • $100 per hour

     ...Founded in 2024, DualEntry is one of the world’s fastest-growing AI startups.   At DualEntry, the future of finance is being...  ...fast with huge momentum - join early.   As our Applied AI Engineer , you'll design and ship production AI systems that transform how... 
    Full time
    Immediate start
    Weekend work

    Dualentry

    New York, NY
    19 hours ago
  • $175k - $225k

     ...Senior AI Engineer About Fonzi AI We're a well-funded, fast-growing startup revolutionizing hiring through AI. Recently launched, we've already attracted thousands of top engineers to our platform. Our vision is to build an AI-powered recruiting marketplace that... 
    Full time
    Live in
    Work at office
    Immediate start
    Flexible hours
    3 days per week

    Fonzi

    New York, NY
    19 hours ago
  • $182.3k - $220k

     ...shipping LLM-powered products across the patient experience, clinical operations, and internal tooling. We're hiring a Senior AI Engineer to join a new team we’re building from the ground up alongside a Senior AI Lead and an Engineering Manager. You'll own AI... 
    Full time
    Local area

    Weight Loss, Better Sex, Fuller Hair, Improved Skin And More...

    New York, NY
    19 hours ago
  • $350k

     ...Description Our client is a 15-person consumer AI company building an agentic travel platform that understands individual preferences...  ...verified options in one conversation. We are hiring an AI Engineer to own the conversational intelligence layer end to end. You... 
    Full time
    H1b

    Our Client

    New York, NY
    19 hours ago
  •  ...StatusNeo is a global AI-native transformation firm helping enterprises design, engineer, and govern AI-led systems with trust at the core. We work with global enterprises across BFSI, retail, healthcare, airlines, and platform-driven industries to transform how... 
    Full time

    Statusneo

    New York, NY
    19 hours ago
  •  ...Edra Edra is solving one of the hardest problems in enterprise AI: AI models are generic but company processes are specific. We build...  ...team in New York and London. We're a deeply technical team of engineers, AI researchers, and strategists with a high bar for talent and... 
    Full time

    Edra

    New York, NY
    19 hours ago
  •  ...Founding AI Engineer (AI + Production) New York City (5 days on-site) · Top of market + equity + benefits TL;DR: Build AI that accelerates nuclear deployment. Own AI production from evals to fine-tuning. Push the frontier on physics models, world models, and AI-accelerated... 
    Full time
    Immediate start
    Weekend work

    Everstar

    New York, NY
    19 hours ago

Do you want to receive more vacancies?

Subscribe and receive similar vacancies to Principal AI Engineer. Be the first to apply!