Principal Scientist (Director), Translational Medicine - Cardiovascular
Merck
Leadership position in translational medicine focused on cardiovascular therapeutic development. Responsible for early clinical strategy from preclinical approval through Phase 2 proof-of-concept, including biomarker development and clinical pharmacology studies in collaboration with discovery and clinical research teams.
Responsibilities
- Lead early clinical development strategy design and execution for novel cardiovascular therapy programs
- Develop and execute biomarker strategies and experimental medicine studies from first-in-human through proof-of-concept phases
- Design clinical pharmacology studies and strategies supporting development phases one through four
- Provide clinical expertise for target identification and validation through preclinical and clinical experiments
- Coordinate Phase 1 study execution and communicate results to governance committees and functional experts
Requirements
- MD or MD/PhD degree
- Proven track record in clinical medicine or clinical research with biomedical research background
- Demonstrated scientific achievement through publications or presentations
- Strong interpersonal, writing, and presentation skills
- Board certification or eligibility in clinical specialty preferred
- Prior translational research or early clinical development experience preferred
- Expertise in cardiovascular medicine or related subspecialties preferred
$260.3k - $409.7k
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