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Principal Mechanical Engineer II (Life Sciences)

Dawar Consulting

Job Description
Our client, a world leader in biotechnology and life sciences, is looking for a " Principal Mechanical Engineer II " based out in Santa Clara, CA .


Job Duration: Long Term Contract (Possibility Of Extension)

Pay Rate : $80/hr on W2

Company Benefits: Medical, Dental, Vision, Paid Sick leave, 401K

Job Summary:

You will lead the design and development of next-generation DNA sequencing instrumentation. This is a hands-on, senior-level role focused on solving complex mechanical challenges at the core of highly integrated life science systems.

Responsibilities:

  • Lead end-to-end mechanical design of complex sub-systems, including electro-mechanical, fluidic, pneumatic, and thermal components
  • Design mechanisms for automated reagent and flow cell handling, sealing, and clamping
  • Architect precision thermal control systems (heating, cooling, sensors, condensation control)
  • Collaborate cross-functionally with electrical, systems, consumables, materials, and assay teams
  • Support system integration, verification, and troubleshooting as the technical owner
  • Drive design reviews, manage technical trade-offs, and deliver design documentation (CAD, drawings, specs)
  • Contribute to future system architecture and technology strategy
Skills / Qualifications:
  • PhD + 5 years, MS + 10 years, or BS + 10+ years in Mechanical Engineering, Bioengineering, or related field
  • Hands-on experience designing complex life science, diagnostic, or automation instrumentation
  • Strong expertise in fluidics systems (pumps, valves, tubing, sensors)
  • Proven experience in thermal management and precision temperature control
  • Advanced proficiency in 3D CAD (SolidWorks preferred)
  • Experience with prototyping, testing, and manufacturing processes (machining, injection molding, 3D printing)
  • Familiarity with Python, LabVIEW, or similar tools for device control and data acquisition
Preferred Qualifications
  • Experience with NGS or genomics instrumentation
  • Use of CFD / FEA to guide design decisions
  • Experience in regulated product development environments
  • Demonstrated technical leadership and mentoring experience

If interested, please send us your updated resume at View email address on click.appcast.io.

Skill Set
Mechanical Design, Fluidics, Thermal Management, 3D CAD
Vacancy posted 4 days ago
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